A novel module regulating ROS in NLR-mediated immunity

The regulatory mechanisms of apoplastic reactive oxygen species (ROS) production during pattern-triggered immunity (PTI) are well known. However, how ROS levels are regulated during effector-triggered immunity (ETI) remains largely unknown. Recently, Zhang et al. discovered that MAPK-Alfin-like 7 module enhances nucleotide-binding, leucine-rich repeat receptor (NLR)-mediated immunity by negatively regulating genes encoding ROS scavenging enzymes, deepening our understanding of ROS control during ETI in plants.

Automated summary

The regulatory mechanisms of apoplastic ROS production in PTI are well known, however, the regulation of ROS levels in ETI is largely unknown. A recent study by Zhang et al. showed that the MAPK-Alfin-like 7 module enhances NLR-mediated immunity by negatively regulating genes encoding ROS scavenging enzymes, providing new insights into ROS control during ETI in plants.