Journal
TRENDS IN GENETICS
Volume 39, Issue 5, Pages 340-341Publisher
CELL PRESS
DOI: 10.1016/j.tig.2023.03.001
Keywords
maternal mRNAs [3]; transcriptome-wide poly(A) tails; dynamic; tive methods; named poly(A) inclusive
Categories
Ask authors/readers for more resources
Using new techniques, Liu et al. found that human maternal mRNAs undergo global poly(A) tail mediated remodeling during the oocyte-to-embryo transition (OET), identified the enzymes involved, and demonstrated the essentiality of remodeling for embryo cleavage.
Understanding a remarkable event at the start of life, the oocyte-to-embryo transition (OET), has remained elusive, especially in humans. Using newly developed techniques, Liu et al. showed that human maternal mRNAs undergo global poly(A) tail mediated remodeling during OET, identified the enzymes involved, and demonstrated the essentiality of remodeling for embryo cleavage.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
