Related references
Note: Only part of the references are listed.Temporal Roles of Platelet and Coagulation Pathways in Collagen- and Tissue Factor-Induced Thrombus Formation
Stefano Navarro et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Roles of Focal Adhesion Kinase PTK2 and Integrin αIIbβ3 Signaling in Collagen- and GPVI-Dependent Thrombus Formation under Shear
Jingnan Huang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Anti-GPVI nanobody blocks collagen- and atherosclerotic plaque-induced GPVI clustering, signaling, and thrombus formation
Natalie J. Jooss et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2022)
Glycoprotein VI - novel target in antiplatelet medication
Oliver Borst et al.
PHARMACOLOGY & THERAPEUTICS (2021)
Nonredundant Roles of Platelet Glycoprotein VI and Integrin αIIbβ3 in Fibrin-Mediated Microthrombus Formation
Gina Perrella et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2021)
Glenzocimab does not impact glycoprotein VI-dependent inflammatory hemostasis
Soumaya Jadoui et al.
HAEMATOLOGICA (2021)
GPVI inhibition by glenzocimab synergistically inhibits atherosclerotic plaque-induced platelet activation when combined with conventional dual antiplatelet therapy
F O Alenazy et al.
EUROPEAN HEART JOURNAL (2021)
Novel antiplatelet strategies targeting GPVI, CLEC-2 and tyrosine kinases
Maan H. Harbi et al.
PLATELETS (2021)
Structural characterization of a novel GPVI-nanobody complex reveals a biologically active domain-swapped GPVI dimer
Alexandre Slater et al.
BLOOD (2021)
Long-term platelet priming after glycoprotein VI stimulation in comparison to Protease-Activating Receptor (PAR) stimulation
Jinmi Zou et al.
PLOS ONE (2021)
Targeting inflammation in atherosclerosis - from experimental insights to the clinic
Oliver Soehnlein et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
Efficacy and Safety of Revacept, a Novel Lesion-Directed Competitive Antagonist to Platelet Glycoprotein VI, in Patients Undergoing Elective Percutaneous Coronary Intervention for Stable Ischemic Heart Disease The Randomized, Double-blind, Placebo-Controlled ISAR-PLASTER Phase 2 Trial
Katharina Mayer et al.
JAMA CARDIOLOGY (2021)
Therapeutic strategies for thrombosis: new targets and approaches
Nigel Mackman et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Population Pharmacokinetic/Pharmacodynamic Modeling of Glenzocimab (ACT017) a Glycoprotein VI Inhibitor of Collagen-Induced Platelet Aggregation
Lionel Renaud et al.
JOURNAL OF CLINICAL PHARMACOLOGY (2020)
Flow studies on human GPVI-deficient blood under coagulating and noncoagulating conditions
Magdolna Nagy et al.
BLOOD ADVANCES (2020)
Safety and Tolerability, Pharmacokinetics, and Pharmacodynamics of ACT017, an Antiplatelet GPVI (Glycoprotein VI) Fab First-in-Human Healthy Volunteer Trial
Christine Voors-Pette et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2019)
Platelet glycoprotein VI genetic quantitative and qualitative defects
Martine Jandrot-Perrus et al.
PLATELETS (2019)
Role of Platelet Glycoprotein VI and Tyrosine Kinase Syk in Thrombus Formation on Collagen-Like Surfaces
Natalie J. Jooss et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
High-throughput elucidation of thrombus formation reveals sources of platelet function variability
Johanna P. van Geffen et al.
HAEMATOLOGICA (2019)
Functional significance of the platelet immune receptors GPVI and CLEC-2
Julie Rayes et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Platelet biology and functions: new concepts and clinical perspectives
Paola E. J. van der Meijden et al.
NATURE REVIEWS CARDIOLOGY (2019)
Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque-triggered thrombus formation in humans
Kristina Busygina et al.
BLOOD (2018)
Immobilized fibrinogen activates human platelets through glycoprotein VI
Pierre H. Mangin et al.
HAEMATOLOGICA (2018)
Immobilized fibrinogen activates human platelets through glycoprotein VI
Pierre H. Mangin et al.
HAEMATOLOGICA (2018)
A synthesis approach of mouse studies to identify genes and proteins in arterial thrombosis and bleeding
Constance C. F. M. J. Baaten et al.
BLOOD (2018)
Glycoprotein VI in securing vascular integrity in inflamed vessels
Yacine Boulaftali et al.
RESEARCH AND PRACTICE IN THROMBOSIS AND HAEMOSTASIS (2018)
Clustering of glycoproteinVI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets
N. S. Poulter et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2017)
Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions
Nicholas Pugh et al.
THROMBOSIS AND HAEMOSTASIS (2017)
Recombinant GPVI-Fc added to single or dual antiplatelet therapy in vitro prevents plaque-induced platelet thrombus formation
Ann-Katrin Mojica Munoz et al.
THROMBOSIS AND HAEMOSTASIS (2017)
Coordinated Membrane Ballooning and Procoagulant Spreading in Human Platelets
Ejaife O. Agbani et al.
CIRCULATION (2015)
Identification of platelet function defects by multi-parameter assessment of thrombus formation
Susanne M. de Witt et al.
NATURE COMMUNICATIONS (2014)
Key role of integrin αIIbβ3 signaling to Syk kinase in tissue factor-induced thrombin generation
Paola E. J. van der Meijden et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2012)
Novel Antiplatelet Drug Revacept (Dimeric Glycoprotein VI-Fc) Specifically and Efficiently Inhibited Collagen-Induced Platelet Aggregation Without Affecting General Hemostasis in Humans
Martin Ungerer et al.
CIRCULATION (2011)
Phase I Study of E7820, an Oral Inhibitor of Integrin alpha-2 Expression with Antiangiogenic Properties, in Patients with Advanced Malignancies
Monica Mita et al.
CLINICAL CANCER RESEARCH (2011)
Platelet adhesion and activation mechanisms in arterial thrombosis and ischaemic stroke
B. Nieswandt et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2011)
Synergism between platelet collagen receptors defined using receptor-specific collagen-mimetic peptide substrata in flowing blood
Nicholas Pugh et al.
BLOOD (2010)
Functional Divergence of Platelet Protein Kinase C (PKC) Isoforms in Thrombus Formation on Collagen
Karen Gilio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Platelet GPVI binds to collagenous structures in the core region of human atheromatous plaque and is critical for atheroprogression in vivo
Christian Schulz et al.
BASIC RESEARCH IN CARDIOLOGY (2008)
Collagen-mimetic peptides mediate flow-dependent thrombus formation by high- or low-affinity binding of integrin α2β1 and glycoprotein VI
I. C. A. Munnix et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2008)
Collagen-type specificity of glycoprotein VI as a determinant of platelet adhesion
Stephanie M. Jung et al.
PLATELETS (2008)
GPVI and α2β1 play independent critical roles during platelet adhesion and aggregate formation to collagen under flow
KL Sarratt et al.
BLOOD (2005)
Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI
S Penz et al.
FASEB JOURNAL (2005)
Adhesion of human and mouse platelets to collagen under shear: a unifying model
JM Auger et al.
FASEB JOURNAL (2005)
The role of collagen in thrombosis and hemostasis
RW Farndale et al.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2004)
Identification of the primary collagen-binding surface on human glycoprotein VI by site-directed mutagenesis and by a blocking phage antibody
PA Smethurst et al.
BLOOD (2004)
Principal role of glycoprotein VI in α2β1 and αIIbβ3 activation during collagen-induced thrombus formation
C Lecut et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
The contributions of the α2β1 integrin to vascular thrombosis in vivo
L He et al.
BLOOD (2003)
Platelet-collagen interaction: is GPVI the central receptor?
B Nieswandt et al.
BLOOD (2003)
Integrin α2-deficient mice develop normally, are fertile, but display partially defective platelet interaction with collagen
O Holtkötter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Glycoprotein VI but not α2β1 integrin is essential for platelet interaction with collagen
B Nieswandt et al.
EMBO JOURNAL (2001)