Azobenzene derivatives of 3,3?-bis(indolyl)methanes: Novel electroactive materials with antioxidant activities

A practical and efficient synthesis of new electroactive azobenzene derivatives of bis(indolyl)methanes has been achieved via the Friedel-Crafts reaction of indole with 5-arylazosalicylaldehydes using propylphosphonic an-hydride (T3P (R)) as an activating agent. This protocol is distinguished by its operational simplicity, high product yields, short reaction time, good functional group tolerance, and environmental friendliness. The antioxidant properties of the synthesized compounds were explored by examining their radical scavenging effect on DPPH radicals and their electrochemical redox behavior was assessed using cyclic voltammetry studies.

Automated summary

A practical and efficient synthesis of new electroactive azobenzene derivatives of bis(indolyl)methanes has been achieved via the Friedel-Crafts reaction using propylphosphonic anhydride as an activating agent. The synthesized compounds showed good antioxidant properties and their electrochemical redox behavior was assessed through cyclic voltammetry studies.