Related references
Note: Only part of the references are listed.Pathogenic Mechanisms of Cytosolic and Membrane-Enriched α-Synudein Converge on Fatty Acid Homeostasis
Arati Tripathi et al.
JOURNAL OF NEUROSCIENCE (2022)
Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy
Saranna Fanning et al.
NPJ PARKINSONS DISEASE (2022)
Upregulation of Cellular Palmitoylation Mitigates α-Synuclein Accumulation and Neurotoxicity
Gary P. H. Ho et al.
MOVEMENT DISORDERS (2021)
Targeted sequencing of Parkinson's disease loci genes highlights SYT11, FGF20 and other associations
Uladzislau Rudakou et al.
BRAIN (2021)
Temperature is a key determinant of alpha- and beta-synuclein membrane interactions in neurons
Nagendran Ramalingam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Synaptotagmin-11 inhibits spontaneous neurotransmission through vti1a
Wan-Ru Li et al.
JOURNAL OF NEUROCHEMISTRY (2021)
Effects of Excess Brain-Derived Human α-Synuclein on Synaptic Vesicle Trafficking
Cristina Roman-Vendrell et al.
FRONTIERS IN NEUROSCIENCE (2021)
Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1
Odetta Antico et al.
SCIENCE ADVANCES (2021)
Altered conformation of a-synuclein drives dysfunction of synaptic vesicles in a synaptosomal model of Parkinson's disease
Luis Fonseca-Ornelas et al.
CELL REPORTS (2021)
Targeted sequencing of Parkinson's disease loci genes highlights SYT11, FGF20 and other associations
Uladzislau Rudakou et al.
BRAIN (2021)
Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling
Alban Ordureau et al.
MOLECULAR CELL (2020)
The diversity of synaptotagmin isoforms
Anne C. Wolfes et al.
CURRENT OPINION IN NEUROBIOLOGY (2020)
Synaptotagmin-11 mediates a vesicle trafficking pathway that is essential for development and synaptic plasticity
Masafumi Shimojo et al.
GENES & DEVELOPMENT (2019)
Lewy pathology in Parkinson's disease consists of crowded organelles and lipid membranes
Sarah H. Shahmoradian et al.
NATURE NEUROSCIENCE (2019)
Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase
Thibaut Imberdis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the SNCA gene
Yixi Chen et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2019)
Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics
Alban Ordureau et al.
MOLECULAR CELL (2018)
GBA1 deficiency negatively affects physiological alpha-synuclein tetramers and related multimers
Sangjune Kim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology
Changhe Wang et al.
NATURE COMMUNICATIONS (2018)
Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission
Ralda Nehme et al.
CELL REPORTS (2018)
Rationally Designed Variants of alpha-Synuclein Illuminate Its in vivo Structural Properties in Health and Disease
Ulf Dettmer
FRONTIERS IN NEUROSCIENCE (2018)
Abrogating Native α-Synuclein Tetramers in Mice Causes a L-DOPA-Responsive Motor Syndrome Closely Resembling Parkinson's Disease
Silke Nuber et al.
NEURON (2018)
α-Synuclein Dimers Impair Vesicle Fission during Clathrin-Mediated Synaptic Vesicle Recycling
Audrey T. Medeiros et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
Global, site-specific analysis of neuronal protein S-acylation
Mark O. Collins et al.
SCIENTIFIC REPORTS (2017)
Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis
Changhe Wang et al.
EMBO REPORTS (2016)
Synaptotagmin XI in Parkinson's disease: New evidence from an association study in Spain and Mexico
Angel Sesar et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2016)
Defects in trafficking bridge Parkinson's disease pathology and genetics
Asa Abeliovich et al.
NATURE (2016)
Phosphorylation induces distinct alpha-synuclein strain formation
Meng-Rong Ma et al.
SCIENTIFIC REPORTS (2016)
Parkinson Disease Mutant E46K Enhances α-Synuclein Phosphorylation in Mammalian Cell Lines, in Yeast, and in Vivo
Martial Kamdem Mbefo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Membrane curvature enables N-Ras lipid anchor sorting to liquid-ordered membrane phases
Jannik Bruun Larsen et al.
NATURE CHEMICAL BIOLOGY (2015)
THE PHYSIOLOGY OF PROTEIN S-ACYLATION
Luke H. Chamberlain et al.
PHYSIOLOGICAL REVIEWS (2015)
Parkinson-causing α-synuclein missense mutations shift native tetramers to monomers as a mechanism for disease initiation
Ulf Dettmer et al.
NATURE COMMUNICATIONS (2015)
α-Synuclein Multimers Cluster Synaptic Vesicles and Attenuate Recycling
Lina Wang et al.
CURRENT BIOLOGY (2014)
Analysis of the Human Tissue-specific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics
Linn Fagerberg et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
Mike A. Nalls et al.
NATURE GENETICS (2014)
In Vivo Cross-linking Reveals Principally Oligomeric Forms of α-Synuclein and β-Synuclein in Neurons and Non-neural Cells
Ulf Dettmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
Yingsha Zhang et al.
NEURON (2013)
Polo-like kinase 2 regulates selective autophagic α-synuclein clearance and suppresses its toxicity in vivo
Abid Oueslati et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
α-SYNUCLEIN PHOSPHORYLATION AND TRUNCATION ARE NORMAL EVENTS IN THE ADULT HUMAN BRAIN
G. Muntane et al.
NEUROSCIENCE (2012)
Mitochondrial Quality Control Mediated by PINK1 and Parkin: Links to Parkinsonism
Derek Narendra et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies
Michael A. Nalls et al.
LANCET (2011)
α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation
Tim Bartels et al.
NATURE (2011)
S-Nitrosylation and S-Palmitoylation Reciprocally Regulate Synaptic Targeting of PSD-95
Gary P. H. Ho et al.
NEURON (2011)
Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus
Michael J. Devine et al.
NATURE COMMUNICATIONS (2011)
Palmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomes
Andrew R. Flannery et al.
JOURNAL OF CELL BIOLOGY (2010)
Curvature Dynamics of α-Synuclein Familial Parkinson Disease Mutants MOLECULAR SIMULATIONS OF THE MICELLE- AND BILAYER-BOUND FORMS
Jason D. Perlmutter et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
α-Synuclein S129 Phosphorylation Mutants Do Not Alter Nigrostriatal Toxicity in a Rat Model of Parkinson Disease
Nikolaus R. McFarland et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2009)
How curved membranes recruit amphipathic helices and protein anchoring motifs
Nikos S. Hatzakis et al.
NATURE CHEMICAL BIOLOGY (2009)
Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction
Hwan-Ching Tai et al.
NATURE REVIEWS NEUROSCIENCE (2008)
Palmitoylated proteins: purification and identification
Junmei Wan et al.
NATURE PROTOCOLS (2007)
Assays of protein palmitoylation
Renaldo C. Drisdel et al.
METHODS (2006)
α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
Antony A. Cooper et al.
SCIENCE (2006)
The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
JJ Zarranz et al.
ANNALS OF NEUROLOGY (2004)
Structural basis for the evolutionary inactivation of Ca2+ binding to synaptotagmin 4
H Dai et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Presynaptic trafficking of synaptotagmin I is regulated by protein palmitoylation
RJ Kang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The autosomal recessive juvenile Parkinson disease gene product, parkin, interacts with and ubiquitinates synaptotagmin XI
DP Huynh et al.
HUMAN MOLECULAR GENETICS (2003)
Palmitoylation sites and processing of synaptotagmin I, the putative calcium sensor for neurosecretion
U Heindel et al.
FEBS LETTERS (2003)
α-Synuclein is phosphorylated in synucleinopathy lesions
H Fujiwara et al.
NATURE CELL BIOLOGY (2002)