Related references
Note: Only part of the references are listed.The dual-function chemokine receptor CCR2 drives migration and chemokine scavenging through distinct mechanisms
Thomas M. Shroka et al.
SCIENCE SIGNALING (2023)
Structures of oxysterol sensor EBI2/GPR183, a key regulator of the immune response
Hongwen Chen et al.
STRUCTURE (2022)
Membrane phosphoinositides regulate GPCR-(3-arrestin complex assembly and dynamics
John Janetzko et al.
CELL (2022)
Ligand-directed bias of G protein signaling at the dopamine D2 receptor
Ee Von Moo et al.
CELL CHEMICAL BIOLOGY (2022)
Arrestin-Dependent and -Independent Internalization of G Protein-Coupled Receptors: Methods, Mechanisms, and Implications on Cell Signaling
Ee Von Moo et al.
MOLECULAR PHARMACOLOGY (2021)
Noncanonical scaffolding of Gαi and β-arrestin by G protein-coupled receptors
Jeffrey S. Smith et al.
SCIENCE (2021)
Receptor-Arrestin Interactions: The GPCR Perspective
Mohammad Seyedabadi et al.
BIOMOLECULES (2021)
Discovery of GPR183 Agonists Based on an Antagonist Scaffold
Viktoria M. S. Kjaer et al.
CHEMMEDCHEM (2021)
EBI2 is expressed in glial cells in multiple sclerosis lesions, and its knock-out modulates remyelination in the cuprizone model
Ilona Klejbor et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2021)
Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction
Jalal Taneera et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)
Wbox2: A clathrin terminal domain-derived peptide inhibitor of clathrin-mediated endocytosis
Zhiming Chen et al.
JOURNAL OF CELL BIOLOGY (2020)
Downregulation of GPR183 on infection restricts the early infection and intracellular replication of mycobacterium tuberculosis in macrophage
Jun Tang et al.
MICROBIAL PATHOGENESIS (2020)
GPCRmd uncovers the dynamics of the 3D-GPCRome
Ismael Rodriguez-Espigares et al.
NATURE METHODS (2020)
GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain
Kathryn Braden et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2020)
GPR183 Regulates Interferons, Autophagy, and Bacterial Growth During Mycobacterium tuberculosis Infection and Is Associated With TB Disease Severity
Stacey Bartlett et al.
FRONTIERS IN IMMUNOLOGY (2020)
Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes
Yu Hisano et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Arrestin-independent constitutive endocytosis of GPR125/ADGRA3
Katja Spiess et al.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2019)
G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?
Krishna Sriram et al.
MOLECULAR PHARMACOLOGY (2018)
EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes
Aleksandra Rutkowska et al.
NEUROPHARMACOLOGY (2018)
EBI2 overexpression in mice leads to B1 B-cell expansion and chronic lymphocytic leukemia-like B-cell malignancies
Kristine Niss Arfelt et al.
BLOOD (2017)
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
Jing Huang et al.
NATURE METHODS (2017)
Migrating Myeloid Cells Sense Temporal Dynamics of Chemoattractant Concentrations
Caren E. Petrie Aronin et al.
IMMUNITY (2017)
Trends in GPCR drug discovery: new agents, targets and indications
Alexander S. Hauser et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK
Morgan O'Hayre et al.
SCIENCE SIGNALING (2017)
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
Alexandre Beautrait et al.
NATURE COMMUNICATIONS (2017)
EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells
Florian Wanke et al.
CELL REPORTS (2017)
Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK
Morgan O'Hayre et al.
SCIENCE SIGNALING (2017)
Biased agonism and allosteric modulation of G protein-coupled receptor 183-a 7TM receptor also known as Epstein-Barr virus-induced gene 2
Viktorija Daugvilaite et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Epstein-Barr Virus-induced Gene 2 Mediates Allergen-induced Leukocyte Migration into Airways
Zhong-Jian Shen et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2017)
Distinct oxysterol requirements for positioning naive and activated dendritic cells in the spleen
Erick Lu et al.
SCIENCE IMMUNOLOGY (2017)
Potential molecular characteristics in situ in response to repetitive UVB irradiation
Wenqi Chen et al.
DIAGNOSTIC PATHOLOGY (2016)
Targeted Elimination of G Proteins and Arrestins Defines Their Specific Contributions to Both Intensity and Duration of G Protein-coupled Receptor Signaling
Elisa Alvarez-Curto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
EBI2 augments Tfh cell fate by promoting interaction with IL-2-quenching dendritic cells
Jianhua Li et al.
NATURE (2016)
Differential CCR7 Targeting in Dendritic Cells by Three Naturally Occurring CC-Chemokines
Gertrud M. Hjorto et al.
FRONTIERS IN IMMUNOLOGY (2016)
Oxysterols regulate encephalitogenic CD4+ T cell trafficking during central nervous system autoimmunity
F. Chalmin et al.
JOURNAL OF AUTOIMMUNITY (2015)
Integrated molecular analysis of adult T cell leukemia/lymphoma
Keisuke Kataoka et al.
NATURE GENETICS (2015)
A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate
Angelique Levoye et al.
FRONTIERS IN ENDOCRINOLOGY (2015)
Oxysterol-EBI2 signaling in immune regulation and viral infection
Viktorija Daugvilaite et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2014)
Identification and Characterization of Small Molecule Modulators of the Epstein-Barr Virus-Induced Gene 2 (EBI2) Receptor
Francois Gessier et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide
Arun K. Shukla et al.
NATURE (2013)
The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells
Dominique Gatto et al.
NATURE IMMUNOLOGY (2013)
Small molecule antagonism of oxysterol-induced Epstein-Barr virus induced gene 2 (EBI2) activation
Tau Benned-Jensen et al.
FEBS OPEN BIO (2013)
Structure-Based Reassessment of the Caveolin Signaling Model: Do Caveolae Regulate Signaling through Caveolin-Protein Interactions?
Brett M. Collins et al.
DEVELOPMENTAL CELL (2012)
Molecular Characterization of Oxysterol Binding to the Epstein-Barr Virus-induced Gene 2 (GPR183)
Tau Benned-Jensen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
CCR2 Acts as Scavenger for CCL2 during Monocyte Chemotaxis
Silvia Volpe et al.
PLOS ONE (2012)
Ligand Modulation of the Epstein-Barr Virus-induced Seven-transmembrane Receptor EBI2 IDENTIFICATION OF A POTENT AND EFFICACIOUS INVERSE AGONIST
Tau Benned-Jensen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
N-Formyl Peptide Receptor 3 (FPR3) Departs from the Homologous FPR2/ALX Receptor with Regard to the Major Processes Governing Chemoattractant Receptor Regulation, Expression at the Cell Surface, and Phosphorylation
Marie-Josephe Rabiet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
EBI2 Operates Independently of but in Cooperation with CXCR5 and CCR7 To Direct B Cell Migration and Organization in Follicles and the Germinal Center
Dominique Gatto et al.
JOURNAL OF IMMUNOLOGY (2011)
Oxysterols direct B-cell migration through EBI2
Changlu Liu et al.
NATURE (2011)
Oxysterols direct immune cell migration via EBI2
Sebastien Hannedouche et al.
NATURE (2011)
Quantitative expression profiling of G-protein-coupled receptors (GPCRs) in metastatic melanoma: the constitutively active orphan GPCR GPR18 as novel drug target
Y. Qin et al.
PIGMENT CELL & MELANOMA RESEARCH (2011)
Modeling Cell Gradient Sensing and Migration in Competing Chemoattractant Fields
Dan Wu et al.
PLOS ONE (2011)
Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types
Jeffery B. Klauda et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2010)
Chemokine receptors intracellular trafficking
Elena M. Borroni et al.
PHARMACOLOGY & THERAPEUTICS (2010)
Biogenesis of Caveolae: Stepwise Assembly of Large Caveolin and Cavin Complexes
Arnold Hayer et al.
TRAFFIC (2010)
Guidance of B Cells by the Orphan G Protein-Coupled Receptor EBI2 Shapes Humoral Immune Responses
Dominique Gatto et al.
IMMUNITY (2009)
ACEMD: Accelerating Biomolecular Dynamics in the Microsecond Time Scale
M. J. Harvey et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2009)
Regulation of Group I Metabotropic Glutamate Receptor Trafficking and Signaling by the Caveolar/Lipid Raft Pathway
Anna Francesconi et al.
JOURNAL OF NEUROSCIENCE (2009)
EBI2 mediates B cell segregation between the outer and centre follicle
Joao P. Pereira et al.
NATURE (2009)
Tickets to ride: selecting cargo for clathrin-regulated internalization
Linton M. Traub
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2009)
Software news and updates - CHARNIM-GUI: A web-based grraphical user interface for CHARMM
Sunhwan Jo et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2008)
Modeling the Role of Homologous Receptor Desensitization in Cell Gradient Sensing
Francis Lin et al.
JOURNAL OF IMMUNOLOGY (2008)
Structural motifs of importance for the constitutive activity of the orphan 7TM receptor EBI2: Analysis of receptor activation in the absence of an agonist
Tau Benned-Jensen et al.
MOLECULAR PHARMACOLOGY (2008)
Unraveling G protein-coupled receptor endocytosis pathways using real-time monitoring of agonist-promoted interaction between β-arrestins and AP-2
Fadi F. Hamdan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
Lily I. Jiang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Molecular pharmacological phenotyping of EBI2 -: An orphan seven-transmembrane receptor with constitutive activity
MM Rosenkilde et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization
MM Paing et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
The structural basis of arrestin-mediated regulation of G-protein-coupled receptors
Vsevolod V. Gurevich et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Transduction of receptor signals by β-arrestins
RJ Leftowitz et al.
SCIENCE (2005)
Regulation of cysteinyl leukotriene type 1 receptor internalization and signaling
S Naik et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?
B Chini et al.
JOURNAL OF MOLECULAR ENDOCRINOLOGY (2004)
Constitutive localization of the gonadotropin-releasing hormone (GnRH) receptor to low density membrane microdomains is necessary for GnRH signaling to ERK
AM Navratil et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Endocytosis of the viral chemokine receptor US28 does not require beta-arrestins but is dependent on the clathrin-mediated pathway
A Fraile-Ramos et al.
TRAFFIC (2003)
Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer - Caveolin-1 (P132L) behaves in a dominant-negative manner and Caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia
H Lee et al.
AMERICAN JOURNAL OF PATHOLOGY (2002)
Localization of the human oxytocin receptor in caveolin-1 enriched domains turns the receptor-mediated inhibition of cell growth into a proliferative response
F Guzzi et al.
ONCOGENE (2002)
β-arrestins regulate protease-activated receptor-1 desensitization but not internalization or down-regulation
MM Paing et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Interaction of caveolin with 7-ketocholesterol
LS Sleer et al.
ATHEROSCLEROSIS (2001)
Classical and new roles of β-arrestins in the regulation of G-protein-coupled receptors
KL Pierce et al.
NATURE REVIEWS NEUROSCIENCE (2001)
Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-β-arrestin complexes after receptor endocytosis
RH Oakley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Differential affinities of visual arrestin, βarrestin1, and βarrestin2 for G protein-coupled receptors delineate two major classes of receptors
RH Oakley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Cholesterol oxidation switches the internalization pathway of endothelin receptor type A from caveolae to clathrin-coated pits in Chinese hamster ovary cells
Y Okamoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Oxytocin receptors and cholesterol: interaction and regulation
G Gimpl et al.
EXPERIMENTAL PHYSIOLOGY (2000)