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Differentially-regulated miRNAs in COVID-19: A systematic review

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INFECTION GENETICS AND EVOLUTION (2021)

Article Virology

Detection of SARS-CoV-2 Derived Small RNAs and Changes in Circulating Small RNAs Associated with COVID-19

Claudius Grehl et al.

Summary: The study conducted high throughput sequencing to analyze small circulating RNAs in the plasma of COVID-19 patients, revealing the presence of SARS-CoV-2 derived small RNAs. These virus-derived small RNAs were detectable even after recovery, and differential abundance of miRNAs discriminated between different severity of cases.

VIRUSES-BASEL (2021)

Article Microbiology

Altered microRNA expression in COVID-19 patients enables identification of SARS-CoV-2 infection

Ryan J. Farr et al.

Summary: This study analyzed the host miRNA response to COVID-19 and identified a three-miRNA signature that can independently classify COVID-19 cases with high accuracy. The findings suggest that miRNA profiling could potentially improve COVID-19 detection and patient management.

PLOS PATHOGENS (2021)

Article Cell Biology

MiRNA Profiling in Plasma and Placenta of SARS-CoV-2-Infected Pregnant Women

Irma Saulle et al.

Summary: Research has shown that the transcriptomic profile of pregnant women is significantly altered in different anatomical districts following SARS-CoV-2 infection, even in the absence of clinical symptoms and vertical transmission. The combination of miRNA and antiviral/immune factors seems to control both the infection and the dysfunctional immune reaction, representing a potential therapeutic target against SARS-CoV-2.

CELLS (2021)

Article Biochemistry & Molecular Biology

SARS-CoV-2-induced Overexpression of miR-4485 Suppresses Osteogenic Differentiation and Impairs Fracture Healing

Bobin Mi et al.

Summary: The upregulation of miR-4485 in COVID-19 patients negatively regulates osteogenic differentiation, potentially targeting Toll-like receptor 4 (TLR-4) and suppressing osteoblastic differentiation in vitro. These findings suggest a promising target for promoting fracture healing and treating osteoporosis in COVID-19 patients.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2021)

Article Multidisciplinary Sciences

Computational analysis of microRNA-mediated interactions in SARS-CoV-2 infection

Muserref Duygu Sacar Demirci et al.

PEERJ (2020)

Article Medical Laboratory Technology

Differential microRNA expression in the peripheral blood from human patients with COVID-19

Caixia Li et al.

JOURNAL OF CLINICAL LABORATORY ANALYSIS (2020)

Article Biochemistry & Molecular Biology

Blood molecular markers associated with COVID-19 immunopathology and multi-organ damage

Yan-Mei Chen et al.

EMBO JOURNAL (2020)

Article Biochemistry & Molecular Biology

Potential role of ACE2-related microRNAs in COVID-19-associated nephropathy

Ahmedz Widiasta et al.

NON-CODING RNA RESEARCH (2020)

Article Physiology

Decreased miR-29b expression is associated with airway inflammation in chronic obstructive pulmonary disease

Kun Tang et al.

AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2019)

Article Medicine, Research & Experimental

miR-423-5p serves as a diagnostic indicator and inhibits the proliferation and invasion of ovarian cancer

Xuebiao Tang et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)

Review Endocrinology & Metabolism

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

Jacob O'Brien et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Review Genetics & Heredity

On the Importance of Host MicroRNAs During Viral Infection

Erika Girardit et al.

FRONTIERS IN GENETICS (2018)

Article Biochemistry & Molecular Biology

Pairing beyond the Seed Supports MicroRNA Targeting Specificity

James P. Broughton et al.

MOLECULAR CELL (2016)

Review Oncology

MicroRNA biogenesis pathways in cancer

Shuibin Lin et al.

NATURE REVIEWS CANCER (2015)

Article Medicine, General & Internal

Frequent Co-Expression of miRNA-5p and-3p Species and Cross-Targeting in Induced Pluripotent Stem Cells

Chiu-Jung Huang et al.

INTERNATIONAL JOURNAL OF MEDICAL SCIENCES (2014)

Article Multidisciplinary Sciences

An integrated encyclopedia of DNA elements in the human genome

Ian Dunham et al.

NATURE (2012)

Review Cell Biology

MicroRNA degradation and turnover: regulating the regulators

Zhuo Zhang et al.

WILEY INTERDISCIPLINARY REVIEWS-RNA (2012)

Review Biotechnology & Applied Microbiology

MicroRNA history: Discovery, recent applications, and next frontiers

Maria I. Almeida et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2011)

Review Cell Biology

MicroRNA control of signal transduction

Masafumi Inui et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)

Review Biochemistry & Molecular Biology

Making RISC

Tomoko Kawamata et al.

TRENDS IN BIOCHEMICAL SCIENCES (2010)

Review Biochemistry & Molecular Biology

MicroRNAs: Target Recognition and Regulatory Functions

David P. Bartel

Review Multidisciplinary Sciences

Small RNAs in transcriptional gene silencing and genome defence

Danesh Moazed

NATURE (2009)

Article Multidisciplinary Sciences

A High-Resolution Structure of the Pre-microRNA Nuclear Export Machinery

Chimari Okada et al.

SCIENCE (2009)

Review Biochemistry & Molecular Biology

MicroRNA function: Multiple mechanisms for a tiny RNA?

RS Pillai

Article Multidisciplinary Sciences

Processing of primary microRNAs by the Microprocessor complex

AM Denli et al.

NATURE (2004)

Article Biochemistry & Molecular Biology

Cytoscape: A software environment for integrated models of biomolecular interaction networks

P Shannon et al.

GENOME RESEARCH (2003)