Trajectory of AKI and hospital mortality among patients with COVID-19

Article Cell & Tissue Engineering

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jitske Jansen et al.

Summary: The study found that SARS-CoV-2 can directly infect kidney cells, leading to cell injury and fibrosis, causing kidney failure. Inhibitors can alleviate the infection.

CELL STEM CELL (2022)

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Article Urology & Nephrology

Short- and Long-Term Recovery after Moderate/Severe AKI in Patients with and without COVID-19

Siao Sun et al.

Summary: The recovery from COVID-19-associated moderate/severe AKI can be predicted using admission data and is associated with the severity of respiratory disease and in-hospital death. The risk of CKD might be similar between COVID-19 positive and negative patients.

KIDNEY360 (2022)

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Article Allergy

Clinical, radiological, and laboratory characteristics and risk factors for severity and mortality of 289 hospitalized COVID-19 patients

Jin-jin Zhang et al.

Summary: The study aims to address the risk factors associated with the severity of COVID-19 patients and the mortality of severe patients. Survived severe and nonsurvived COVID-19 patients had distinct clinical and laboratory characteristics, which were separated by principal component analysis. Risk factors for mortality of severe COVID-19 patients include elder age, increased number of affected lobes, higher levels of serum CRP, chest tightness/dyspnea, and smoking history.

ALLERGY (2021)

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Review Infectious Diseases

Risk factors for Covid-19 severity and fatality: a structured literature review

Dominik Wolff et al.

Summary: A systematic literature review on the risk factors of severe and fatal Covid-19 courses shows that conditions and comorbidities related to poor health status, high age, obesity, diabetes, and hypertension are risk factors for severe and fatal disease courses. Additionally, organ damage and coagulation dysfunctions are associated with severe and fatal courses of the disease.

INFECTION (2021)

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Article Virology

Anemia is associated with severe illness in COVID-19: A retrospective cohort study

Zheying Tao et al.

Summary: The study evaluated the impact of anemia on COVID-19 patients and found that anemia is associated with the severity of COVID-19, with anemic patients more likely to have comorbidities and severe illness. Anemia was related to elevated levels of CRP, PCT, and other laboratory indices, and was positively associated with the severity of COVID-19 in terms of dyspnea, CRP, and PCT.

JOURNAL OF MEDICAL VIROLOGY (2021)

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Article Urology & Nephrology

Acute kidney injury and mortality risk in older adults with COVID-19

Hong Xu et al.

Summary: Older patients hospitalized with COVID-19 had a higher incidence of AKI compared to patients hospitalized for other diagnoses. COVID-19 and reduced baseline kidney function were risk factors for developing AKI. AKI and COVID-19 were associated with in-hospital death.

JOURNAL OF NEPHROLOGY (2021)

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Article Urology & Nephrology

Acute kidney injury in COVID-19: multicentre prospective analysis of registry data

Yize Wan et al.

Summary: Analysis of AKI data in COVID-19 patients reveals that AKI significantly increases mortality, with severity of AKI positively associated with mortality. Persistent AKI is linked to higher mortality rates.

CLINICAL KIDNEY JOURNAL (2021)

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Review Urology & Nephrology

Pathophysiology of COVID-19-associated acute kidney injury

Matthieu Legrand et al.

Summary: Acute kidney injury (AKI) is a common complication of COVID-19, and potential mechanisms for COVID-19-associated AKI include systemic haemodynamic instability, local immune cell infiltration, and endothelial injury, which may lead to impaired kidney function.

NATURE REVIEWS NEPHROLOGY (2021)

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Article Health Care Sciences & Services

Association of persistent acute kidney injury and renal recovery with mortality in hospitalised patients

Tezcan Ozrazgat-Baslanti et al.

Summary: The study found that persistent AKI and the absence of renal recovery are associated with reduced long-term survival, independent of AKI severity. Therefore, it is essential to identify patients at risk of developing persistent AKI and no renal recovery to guide treatment-related decisions.

BMJ HEALTH & CARE INFORMATICS (2021)

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Article Medicine, General & Internal

Clinical Characteristics of Coronavirus Disease 2019 in China

W. Guan et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

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Article Critical Care Medicine

Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan A Retrospective Observational Study

Yingzhen Du et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2020)

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Editorial Material Urology & Nephrology

Defining Early Recovery of Acute Kidney Injury

Stephen Duff et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

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Article Critical Care Medicine

Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study

Xiaobo Yang et al.

Lancet Respiratory Medicine (2020)

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Article Urology & Nephrology

Renal Involvement and Early Prognosis in Patients with COVID-19 Pneumonia

Guangchang Pei et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

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Article Urology & Nephrology

Kidney disease is associated with in-hospital death of patients with COVID-19

Yichun Cheng et al.

KIDNEY INTERNATIONAL (2020)

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Article Urology & Nephrology

Acute kidney injury in patients hospitalized with COVID-19

Jamie S. Hirsch et al.

KIDNEY INTERNATIONAL (2020)

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Article Medicine, General & Internal

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study

Fei Zhou et al.

LANCET (2020)

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Editorial Material Urology & Nephrology

Kidney involvement in COVID-19 and rationale for extracorporeal therapies

Claudio Ronco et al.

NATURE REVIEWS NEPHROLOGY (2020)

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Article Infectious Diseases

Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China

J. Zhang et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

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Article Urology & Nephrology

Outcomes for Patients With COVID-19 and Acute Kidney Injury: A Systematic Review and Meta-Analysis

Shelief Y. Robbins-Juarez et al.

Kidney International Reports (2020)

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Review Urology & Nephrology

Acute Kidney Injury in the 2019 Novel Coronavirus Disease

Jing-Yi Qian et al.

KIDNEY DISEASES (2020)

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Article Urology & Nephrology

COVID-19-Associated Kidney Injury: A Case Series of Kidney Biopsy Findings

Purva Sharma et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

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Article Urology & Nephrology

AKI in Hospitalized Patients with and without COVID-19: A Comparison Study

Molly Fisher et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

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Editorial Material Urology & Nephrology

Histopathologic and Ultrastructural Findings in Postmortem Kidney Biopsy Material in 12 Patients with AKI and COVID-19

Pouneh Golmai et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2020)

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Article Urology & Nephrology

COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

Mitra K. Nadim et al.

NATURE REVIEWS NEPHROLOGY (2020)

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Article Transplantation

Early versus late acute kidney injury among patients with COVID-19-a multicenter study from Wuhan, China

Suyuan Peng et al.

NEPHROLOGY DIALYSIS TRANSPLANTATION (2020)

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Article Multidisciplinary Sciences

Long-term survival in patients with septic acute kidney injury is strongly influenced by renal recovery

Marco Fiorentino et al.

PLOS ONE (2018)

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Review Urology & Nephrology

The prognostic importance of duration of AKI: a systematic review and meta-analysis

Swati Mehta et al.

BMC NEPHROLOGY (2018)

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Article Urology & Nephrology

Acute kidney disease and renal recovery: consensus report of the Acute Disease Quality Initiative (ADQI) 16 Workgroup

Lakhmir S. Chawla et al.

NATURE REVIEWS NEPHROLOGY (2017)

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Article Multidisciplinary Sciences

The association between renal recovery after acute kidney injury and long-term mortality after transcatheter aortic valve replacement

Charat Thongprayoon et al.

PLOS ONE (2017)

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Article Critical Care Medicine

The Effects of Alternative Resuscitation Strategies on Acute Kidney Injury in Patients with Septic Shock

John. A. Kellum et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2016)

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Article Urology & Nephrology

Association between AKI, Recovery of Renal Function, and Long-Term Outcomes after Hospital Discharge

Neesh Pannu et al.

CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2013)

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Article Cardiac & Cardiovascular Systems

Impact of Recovery of Renal Function on Long-Term Mortality After Coronary Artery Bypass Grafting

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AMERICAN JOURNAL OF CARDIOLOGY (2010)

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Acute Kidney Injury Is Associated With Increased Long-Term Mortality After Cardiothoracic Surgery

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CIRCULATION (2009)

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Prognosis for long-term survival and renal recovery in critically ill patients with severe acute renal failure: a population-based study

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CRITICAL CARE (2005)

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Review Oncology

Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome

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JOURNAL OF PATHOLOGY (2004)

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Trajectory of AKI and hospital mortality among patients with COVID-19

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