Flexible and water-soluble polythiophene carboxylate for selective appraisal of acebutolol in aqueous samples

This study investigates the effectiveness, selectivity, and electrochemical properties of water-soluble poly-thiophene carboxylic acid-modified glassy carbon electrode (PTPh3C/GCE) for detecting acebutolol (ACE) in the presence of a variety of water sources. Initially, conjugated PTPh3C polymer was synthesized via polymerization and further characterized by spectroscopic and analytical methods. Electrochemical impedance spectroscopy (EIS) investigates the resistivity of the electrodes, and PTPh3C/GCE exhibited a low resistivity (Rct = 80 omega) than bare GCE (Rct = 275 omega). In optimal conditions, the constructed sensor exhibited a wide linear range of 0.009-616 mu M, low detection limit (3.1 nM), good sensitivity (0.22 mu A mu M-1 cm-2), and high selectivity. In addition, the proposed sensor was successfully used to detect ACE in environmental water sample outcomes with satisfactory recoveries.

Automated summary

This study explores the performance of a water-soluble poly-thiophene carboxylic acid-modified glassy carbon electrode (PTPh3C/GCE) for detecting acebutolol (ACE) in various water sources. The sensor exhibited a wide linear range, low detection limit, good sensitivity, and high selectivity. It was successfully used to detect ACE in environmental water samples with satisfactory recoveries.