4.7 Article

Subgroups of borderline personality disorder: A latent class analysis

Journal

PSYCHIATRY RESEARCH
Volume 323, Issue -, Pages -

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2023.115131

Keywords

Symptom profiles; Symptom groups; Treatment Implications

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Borderline personality disorder (BPD) is characterized by instability in various domains. This study identified three subgroups of BPD symptoms, namely the non-labile type, dissociative/paranoid type, and interpersonally unstable type. These subgroups may have implications for refining BPD treatment interventions.
Borderline personality disorder (BPD) is characterized by instability in interpersonal, affective, cognitive, self-identity, and behavioral domains. For a BPD diagnosis, individuals must present at least five of nine symp-toms, resulting in 256 possible symptom combinations; thus, individuals diagnosed with BPD can differ sub-stantially. Specific symptoms of BPD tend to co-occur, suggesting BPD subgroups. To explore this potential, we analyzed data from 504 participants diagnosed with BPD enrolled in one of three randomized controlled trials conducted at center for Addiction and Mental Health in Toronto, Canada from 2002 to 2018. An exploratory latent class analysis (LCA) was conducted to identify symptom subgroups of BPD. Analyses indicated three latent subgroups. The first group (n = 53) is distinguished by a lack of affective instability and low levels of dissociative symptoms (non-labile type). The second group (n = 279) is characterized by high levels of dissociative and paranoid symptoms but low abandonment fears and identity disturbance (dissociative/paranoid type). The third group (n = 172) is characterized by high efforts to avoid abandonment and interpersonal aggression (inter-personally unstable type). Homogenous symptom subgroups of BPD symptoms exist and may have important implications for how to refine BPD treatment interventions.

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