Journal
JOURNAL OF VIROLOGY
Volume 90, Issue 19, Pages 8389-8394Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JVI.00041-16
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Funding
- Deutsche Forschungsgemeinschaft (DFG) [SFB 1021, SPP 1596]
- Japan Society for the Promotion of Science (JSPS)
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The nonstructural protein NS1 is well established as a virulence factor of influenza A virus counteracting induction of the antiviral type I interferon system. Recent studies now show that viral structural proteins, their derivatives, and even the genome itself also contribute to keeping the host defense under control. Here, we summarize the current knowledge on these NS1-independent interferon escape strategies.
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