Detection of Virus SARS-CoV-2 Using a Surface Plasmon Resonance Device Based on BiFeO3-Graphene Layers

Coronavirus disease (COVID-19) pandemic outbreak is being investigated by severe respirational syndrome coronavirus-2 (SARS-CoV-2) as a global health issue. It is crucial to propose sensitive and rapid coronavirus detectors. Herein, we propose a biosensor based on surface plasmon resonance (SPRE) for the detection of SARS-CoV-2 virus. To achieve improved sensitivity, a BiFeO3 layer is inserted between a metal (Ag) thin film and a graphene layer in the proposed SPRE device so that it has the structure BK7 prism/ Ag/ BiFeO3/ graphene/ analyte. It has been demonstrated that a small variation in the refractive index of the analyte can cause a considerable shift in the resonance angle caused by the remarkable dielectric properties of the BiFeO3 layer, which include a high index of refraction and low loss. The proposed device has shown an extremely high sensitivity of 293 deg/RIU by optimizing the thicknesses of Ag, BiFeO3, and the number of graphene sheets. The proposed SPRE-based sensor is encouraging for use in various sectors of biosensing because of its high sensitivity.

Automated summary

The COVID-19 pandemic caused by SARS-CoV-2 is a global health issue, requiring sensitive and rapid detection methods for the virus. In this study, a biosensor based on surface plasmon resonance (SPRE) is proposed for detecting SARS-CoV-2. By inserting a BiFeO3 layer between a metal (Ag) thin film and a graphene layer, the proposed SPRE device achieved improved sensitivity. The device demonstrated a high sensitivity of 293 deg/RIU by optimizing the thicknesses of Ag, BiFeO3, and the number of graphene sheets. This SPRE-based sensor shows promise for various applications in biosensing due to its high sensitivity.