Effect of photodynamic therapy for oral potentially malignant disorders: How should we evaluate it?

Letter Dentistry, Oral Surgery & Medicine

Focus on DNA-aneuploidy cytology relationship with dysplasia and clinical features in OPMDs

Wei Liu et al.

ORAL DISEASES (2022)

Article Oncology

Evaluation of Static DNA Ploidy Analysis Using Conventional Brush Biopsy-Based Cytology Samples as an Adjuvant Diagnostic Tool for the Detection of a Malignant Transformation in Potentially Oral Malignant Diseases: A Prospective Study

Natalie Bechstedt et al.

Summary: This study confirms the effectiveness of DNA ploidy analysis in the detection of oral cancer, providing a non-invasive and patient-friendly diagnostic tool.

CANCERS (2022)

Add to Collection

Article Multidisciplinary Sciences

Application of 5-aminolevulinic acid-mediated Waterlase-assisted photodynamic therapy in the treatment of oral leukoplakia

Jiali Ou et al.

Summary: Photodynamic therapy (PDT) combined with laser irradiation shows promising and safe efficacy in the treatment of oral leukoplakia (OL). ALA-mediated PDT combined with YSGG is effective for OL with mild to moderate dysplasia, but further investigation is needed for severe dysplasia due to potential undesirable effects.

SCIENTIFIC REPORTS (2022)

Add to Collection

Review Dentistry, Oral Surgery & Medicine

Oral potentially malignant disorders: A consensus report from an international seminar on nomenclature and classification, convened by the WHO Collaborating Centre for Oral Cancer

Saman Warnakulasuriya et al.

Summary: Oral potentially malignant disorders (OPMDs) are associated with an increased risk of oral cancer, and an expert group updated the nomenclature and classification of OPMDs, adding oral lichenoid lesions and oral manifestations of 'chronic graft-versus-host disease' to the list. It is recommended to establish a global research consortium to study the natural history of OPMDs based on the proposed classification.

ORAL DISEASES (2021)

Add to Collection

Review Dentistry, Oral Surgery & Medicine

Oral epithelial dysplasia: Recognition, grading and clinical significance

Edward Odell et al.

Summary: Histopathological grading of epithelial dysplasia is crucial for assessing the risk of malignant transformation in oral potentially malignant disorders (OPMDs). Current views on molecular pathogenesis, histological interpretation, and the use of grading systems are discussed. The implications of finding epithelial dysplasia in an oral biopsy for clinical management are also highlighted from the pathologists' viewpoint.

ORAL DISEASES (2021)

Add to Collection

Review Dentistry, Oral Surgery & Medicine

Management of oral potentially malignant disorders

Alexander Ross Kerr et al.

Summary: Managing patients with oral potentially malignant disorders is challenging due to the lack of understanding of natural history and validated predictive markers. Evidence-based health promotion is not widely embraced, and research on medical interventions often suffers from methodologic flaws and lack of focus on patient quality of life. Global networks with well-characterized patient populations are needed for better intervention trials.

ORAL DISEASES (2021)

Add to Collection

Article Oncology