Related references
Note: Only part of the references are listed.1,8-Cineole ameliorates right ventricle dysfunction associated with pulmonary arterial hypertension by restoring connexin43 and mitochondrial homeostasis
Jorge M. Alves-Silva et al.
PHARMACOLOGICAL RESEARCH (2022)
Chronic Sigma 1 receptor activation alleviates right ventricular dysfunction secondary to pulmonary arterial hypertension
Yazhou Sun et al.
BIOENGINEERED (2022)
Celastrol attenuates the remodeling of pulmonary vascular and right ventricular in monocrotaline-induced pulmonary arterial hypertension in rats
Huayang Li et al.
CARDIOVASCULAR DIAGNOSIS AND THERAPY (2022)
Cardiac Fibrosis in the Pressure Overloaded Left and Right Ventricle as a Therapeutic Target
Katharina Schimmel et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2022)
Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension
Ruaa Al-Qazazi et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2022)
Proteomic and Metabolomic Analyses of Right Ventricular Failure due to Pulmonary Arterial Hypertension
Xiaohan Qin et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2022)
Integrins in cardiac fibrosis
Ruoshui Li et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2022)
The inflammation-resolution promoting molecule resolvin-D1 prevents atrial proarrhythmic remodelling in experimental right heart disease
Roddy Hiram et al.
CARDIOVASCULAR RESEARCH (2021)
Acetazolamide Improves Right Ventricular Function and Metabolic Gene Dysregulation in Experimental Pulmonary Arterial Hypertension
Fotios Spyropoulos et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2021)
Identification of Celastrol as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension and Right Ventricular Failure Through Suppression of Bsg (Basigin)/CyPA (Cyclophilin A)
Ryo Kurosawa et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2021)
BKCa Channel Activation Attenuates the Pathophysiological Progression of Monocrotaline-Induced Pulmonary Arterial Hypertension in Wistar Rats
Ana Paula Ferraz et al.
CARDIOVASCULAR DRUGS AND THERAPY (2021)
Seamless Genetic Recording of Transiently Activated Mesenchymal Gene Expression in Endothelial Cells During Cardiac Fibrosis
Shaohua Zhang et al.
CIRCULATION (2021)
Diverse origins and activation of fibroblasts in cardiac fibrosis
Preetinder K. Aujla et al.
CELLULAR SIGNALLING (2021)
Transcriptomic Analysis of Right Ventricular Remodeling in Two Rat Models of Pulmonary Hypertension Identification and Validation of Epithelial-to-Mesenchymal Transition in Human Right Ventricular Failure
John F. Park et al.
CIRCULATION-HEART FAILURE (2021)
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload
Yan Zou et al.
CELL DEATH & DISEASE (2021)
Improving Right Ventricular Function by Increasing BMP Signaling with FK506
Mario Boehm et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2021)
Sotatercept for the Treatment of Pulmonary Arterial Hypertension
Marc Humbert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Cardiac Fibrosis: Key Role of Integrins in Cardiac Homeostasis and Remodeling
Patrick B. Meagher et al.
CELLS (2021)
α7 Nicotinic acetylcholine receptor mediates right ventricular fibrosis and diastolic dysfunction in pulmonary hypertension
Alexander Vang et al.
JCI INSIGHT (2021)
WNT/β-Catenin Signaling Promotes TGF-β-Mediated Activation of Human Cardiac Fibroblasts by Enhancing IL-11 Production
Edyta Dzialo et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
Quercetin, Perillyl Alcohol, and Berberine Ameliorate Right Ventricular Disorders in Experimental Pulmonary Arterial Hypertension: Effects on miR-204, miR-27a, Fibrotic, Apoptotic, and Inflammatory Factors
Soodeh Rajabi et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2021)
Myocardial T1-mapping and extracellular volume in pulmonary arterial hypertension: A systematic review and meta-analysis
Samer Alabed et al.
MAGNETIC RESONANCE IMAGING (2021)
Pirfenidone in heart failure with preserved ejection fraction: a randomized phase 2 trial
Gavin A. Lewis et al.
NATURE MEDICINE (2021)
An Insight on Multicentric Signaling of Angiotensin II in Cardiovascular system: A Recent Update
Kanika Verma et al.
FRONTIERS IN PHARMACOLOGY (2021)
Selective Myeloid Depletion of Galectin-3 Offers Protection Against Acute and Chronic Lung Injury
Duncan C. Humphries et al.
FRONTIERS IN PHARMACOLOGY (2021)
Cardiac Fibrosis and Fibroblasts
Hitoshi Kurose
CELLS (2021)
SGLT2 inhibitors decrease cardiovascular death and heart failure hospitalizations in patients with heart failure: A systematic review and meta-analysis
Rhanderson Cardoso et al.
ECLINICALMEDICINE (2021)
Cardiac fibrosis
Nikolaos G. Frangogiannis
CARDIOVASCULAR RESEARCH (2021)
Lansoprazole alleviates pressure overload-induced cardiac hypertrophy and heart failure in mice by blocking the activation of beta-catenin
Hairuo Lin et al.
CARDIOVASCULAR RESEARCH (2020)
Delineating the molecular and histological events that govern right ventricular recovery using a novelmouse model of pulmonary artery de-banding
Mario Boehm et al.
CARDIOVASCULAR RESEARCH (2020)
Sulforaphane prevents right ventricular injury and reduces pulmonary vascular remodeling in pulmonary arterial hypertension
Yin Kang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2020)
Cardiac Fibroblast Diversity
Michelle D. Tallquist
ANNUAL REVIEW OF PHYSIOLOGY, VOL 82 (2020)
The SGLT2 inhibitor empagliflozin reduces mortality and prevents progression in experimental pulmonary hypertension
Biswajit Chowdhury et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Gal-3 (Galectin-3) and KCa3.1 Mediate Heterogeneous Cell Coupling and Myocardial Fibrogenesis Driven by βAR (β-Adrenoceptor) Activation
Gang She et al.
HYPERTENSION (2020)
Ursolic Acid Improves Monocrotaline-Induced Right Ventricular Remodeling by Regulating Metabolism
Xiaojian Gao et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2020)
Diffuse right ventricular fibrosis in heart failure with preserved ejection fraction and pulmonary hypertension
Ravi B. Patel et al.
ESC HEART FAILURE (2020)
Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts
Sarika Saraswati et al.
FASEB JOURNAL (2020)
Cardiac Fibrosis and Cardiac Fibroblast Lineage-Tracing: Recent Advances
Xing Fu et al.
FRONTIERS IN PHYSIOLOGY (2020)
Targeting the renin-angiotensin-aldosterone system in fibrosis
Mohammad AlQudah et al.
MATRIX BIOLOGY (2020)
Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension
Junichi Omura et al.
CIRCULATION (2020)
Myofibroblasts and Fibrosis Mitochondrial and Metabolic Control of Cellular Differentiation
Andrew A. Gibb et al.
CIRCULATION RESEARCH (2020)
TGF-β and WNT signaling pathways in cardiac fibrosis: non-coding RNAs come into focus
Fatemeh Yousefi et al.
CELL COMMUNICATION AND SIGNALING (2020)
Pulmonary artery banding is a relevant model to study the right ventricular remodeling and dysfunction that occurs in pulmonary arterial hypertension
Yohei Akazawa et al.
JOURNAL OF APPLIED PHYSIOLOGY (2020)
Heart Rate Reduction Improves Right Ventricular Function and Fibrosis in Pulmonary Hypertension
Ryo Ishii et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2020)
Polyphyllin I attenuates pressure over-load induced cardiac hypertrophy via inhibition of Wnt/β-catenin signaling pathway
Qing Li et al.
LIFE SCIENCES (2020)
Magnesium lithospermate B improves pulmonary artery banding induced right ventricular dysfunction by alleviating inflammation via p38MAPK pathway
Chen Qu et al.
PULMONARY PHARMACOLOGY & THERAPEUTICS (2020)
Cells of the adult human heart
Monika Litvinukova et al.
NATURE (2020)
Noncanonical WNT Activation in Human Right Ventricular Heart Failure
Jonathan J. Edwards et al.
FRONTIERS IN CARDIOVASCULAR MEDICINE (2020)
Bisoprolol therapy does not reduce right ventricular sympathetic activity in pulmonary arterial hypertension patients
Mischa T. Rijnierse et al.
PULMONARY CIRCULATION (2020)
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension
Nina Rol et al.
CARDIOVASCULAR RESEARCH (2019)
Inhibition of TLR9-NF-κB-mediated sterile inflammation improves pressure overload-induced right ventricular dysfunction in rats
Keimei Yoshida et al.
CARDIOVASCULAR RESEARCH (2019)
Galectin-3: A Harbinger of Reactive Oxygen Species, Fibrosis, and Inflammation in Pulmonary Arterial Hypertension
David J. R. Fulton et al.
ANTIOXIDANTS & REDOX SIGNALING (2019)
Anatomy, Function, and Dysfunction of the Right Ventricle JACC State-of-the-Art Review
Javier Sanz et al.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)
Treatment of Pulmonary Hypertension With Angiotensin II Receptor Blocker and Neprilysin Inhibitor Sacubitril/Valsartan
Richard T. Clements et al.
CIRCULATION-HEART FAILURE (2019)
Reversal of right ventricular failure by chronic α1A-subtype adrenergic agonist therapy
Patrick M. Cowley et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2019)
Disconnect between Fibrotic Response and Right Ventricular Dysfunction
Slaven Crnkovic et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2019)
Nitric Oxide Synthase 2 Induction Promotes Right Ventricular Fibrosis
Mario Boehm et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2019)
Right Ventricular Fibrosis: A Pathophysiological Factor in Pulmonary Hypertension?
Stine Andersen et al.
CIRCULATION (2019)
Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension
Paul-Benoit Poble et al.
FASEB JOURNAL (2019)
17-estradiol preserves right ventricular function in rats with pulmonary arterial hypertension: an echocardiographic and histochemical study
Yi-Dan Wang et al.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING (2019)
Acetaldehyde dehydrogenase 2 deficiency exacerbates cardiac fibrosis by promoting mobilization and homing of bone marrow fibroblast progenitor cells
Xiao Li et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2019)
Beneficial effects of mesenchymal stem cell delivery via a novel cardiac bioscaffold on right ventricles of pulmonary arterial hypertensive rats
Eric G. Schmuck et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2019)
Pressure overload induced right ventricular remodeling is not attenuated by the anti-fibrotic agent pirfenidone
Stine Andersen et al.
PULMONARY CIRCULATION (2019)
Transient receptor potential vanilloid-3 (TRPV3) activation plays a central role in cardiac fibrosis induced by pressure overload in rats via TGF-β1 pathway
Yan Liu et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2018)
Elastin, arterial mechanics, and cardiovascular disease
Austin J. Cocciolone et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2018)
ASK1 Inhibition Halts Disease Progression in Preclinical Models of Pulmonary Arterial Hypertension
Grant R. Budas et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)
A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension
Anna R. Hemnes et al.
EUROPEAN RESPIRATORY JOURNAL (2018)
CTGF/CCN2 is an autocrine regulator of cardiac fibrosis
Lisa E. Dorn et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2018)
Defining the molecular signatures of human right heart failure
Jordan L. Williams et al.
LIFE SCIENCES (2018)
Sustained β-AR stimulation induces synthesis and secretion of growth factors in cardiac myocytes that affect on cardiac fibroblast activation
Narawat Nuamnaichati et al.
LIFE SCIENCES (2018)
PPARγ agonist pioglitazone reverses pulmonary hypertension and prevents right heart failure via fatty acid oxidation
Ekaterina Legchenko et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Eplerenone attenuates pathological pulmonary vascular rather than right ventricular remodeling in pulmonary arterial hypertension
Mario Boehm et al.
BMC PULMONARY MEDICINE (2018)
TGF-β and BMPR2 Signaling in PAH: Two Black Sheep in One Family
Nina Rol et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Inflammation in Right Ventricular Failure: Does It Matter?
Laurence Dewachter et al.
FRONTIERS IN PHYSIOLOGY (2018)
The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction
Dennis M. Abraham et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Native T1 mapping and extracellular volume fraction measurement for assessment of right ventricular insertion point and septal fibrosis in chronic thromboembolic pulmonary hypertension
Fritz C. Roller et al.
EUROPEAN RADIOLOGY (2017)
Detection of right ventricular myocardial fibrosis using quantitative CT attenuation of the right ventricular myocardium in the late phase on 320 slice CT in subjects with pulmonary hypertension
Koya Ozawa et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2017)
Wnt5a is elevated in heart failure and affects cardiac fibroblast function
Aurelija Abraityte et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2017)
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4
Jingni He et al.
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION (2017)
Beta 2-adrenergic receptor agonists are novel regulators of macrophage activation in diabetic renal and cardiovascular complications
Hyunjin Noh et al.
KIDNEY INTERNATIONAL (2017)
Anti-fibrotic effects of soluble guanylate cyclase stimulators and activators: A review of the preclinical evidence
Peter Sandner et al.
RESPIRATORY MEDICINE (2017)
Loss of β-catenin in resident cardiac fibroblasts attenuates fibrosis induced by pressure overload in mice
Fu-Li Xiang et al.
NATURE COMMUNICATIONS (2017)
Wnt5a is associated with right ventricular dysfunction and adverse outcome in dilated cardiomyopathy
Aurelija Abraityte et al.
SCIENTIFIC REPORTS (2017)
Right ventricular recovery after bilateral lung transplantation for pulmonary arterial hypertension
Thomas M. Gorter et al.
INTERACTIVE CARDIOVASCULAR AND THORACIC SURGERY (2017)
Mineralocorticoid Receptor Signaling as a Therapeutic Target for Renal and Cardiac Fibrosis
Greg H. Tesch et al.
FRONTIERS IN PHARMACOLOGY (2017)
The Soft-and Hard-Heartedness of Cardiac Fibroblasts: Mechanotransduction Signaling Pathways in Fibrosis of the Heart
Kate M. Herum et al.
JOURNAL OF CLINICAL MEDICINE (2017)
α1A-Subtype adrenergic agonist therapy for the failing right ventricle
Patrick M. Cowley et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2017)
Fibroblasts and the extracellular matrix in right ventricular disease
Nikolaos G. Frangogiannis
CARDIOVASCULAR RESEARCH (2017)
Role of cardiac inflammation in right ventricular failure
Xiao-Qing Sun et al.
CARDIOVASCULAR RESEARCH (2017)
p38 MAPK Inhibition Improves Heart Function in Pressure-Loaded Right Ventricular Hypertrophy
Baktybek Kojonazarov et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2017)
Pulmonary arterial hypertension treatment with carvedilol for heart failure: a randomized controlled trial
Samar Farha et al.
JCI INSIGHT (2017)
Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis
Jeffery D. Molkentin et al.
CIRCULATION (2017)
The cardiovascular benefits of empagliflozin: SGLT2-dependent and -independent effects
Roberto Vettor et al.
DIABETOLOGIA (2017)
Galectin-3 levels are associated with right ventricular functional and morphologic changes in pulmonary arterial hypertension
Brett E. Fenster et al.
HEART AND VESSELS (2016)
Mesenchymal stem cells preserve neonatal right ventricular function in a porcine model of pressure overload
Brody Wehman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2016)
17β-Estradiol mediates superior adaptation of right ventricular function to acute strenuous exercise in female rats with severe pulmonary hypertension
Tim Lahm et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2016)
Tensile mechanical properties of collagen type I and its enzymatic crosslinks
Albert L. Kwansa et al.
BIOPHYSICAL CHEMISTRY (2016)
Bone Morphogenetic Protein Receptor Type 2 Mutation in Pulmonary Arterial Hypertension A View on the Right Ventricle
Cathelijne E. van der Bruggen et al.
CIRCULATION (2016)
Cardiac Fibrosis The Fibroblast Awakens
Joshua G. Travers et al.
CIRCULATION RESEARCH (2016)
Right Ventricular Myocardial Stiffness in Experimental Pulmonary Arterial Hypertension Relative Contribution of Fibrosis and Myofibril Stiffness
Silvia Rain et al.
Circulation-Heart Failure (2016)
Peroxisome proliferator-activated receptors in cardiacenergy metabolism and cardiovascular disease
Thekkuttuparambil Ananthanarayanan Ajith et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2016)
MicroRNAs in heart failure: from biomarker to target for therapy
Eline L. Vegter et al.
EUROPEAN JOURNAL OF HEART FAILURE (2016)
Bisoprolol in idiopathic pulmonary arterial hypertension: an explorative study
Jasmijn S. J. A. van Campen et al.
EUROPEAN RESPIRATORY JOURNAL (2016)
Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway
Jing Wang et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2016)
Galectin-3 and aldosterone as potential tandem biomarkers in pulmonary arterial hypertension
Laurent Calvier et al.
HEART (2016)
Nitrite Prevents Right Ventricular Failure and Remodeling Induced by Pulmonary Artery Banding
Jian Hu et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2016)
Integrins and integrin-related proteins in cardiac fibrosis
Chao Chen et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Epicardium-derived fibroblasts in heart development and disease
Ming Fang et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2016)
Hypoxia-stimulated cardiac fibroblast production of IL-6 promotes myocardial fibrosis via the TGF-β1 signaling pathway
Jia-Hong Wang et al.
LABORATORY INVESTIGATION (2016)
Pioglitazone alleviates cardiac and vascular remodelling and improves survival in monocrotaline induced pulmonary arterial hypertension
Arnica Behringer et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2016)
Age-Dependent Effect of Pediatric Cardiac Progenitor Cells After Juvenile Heart Failure
Udit Agarwal et al.
STEM CELLS TRANSLATIONAL MEDICINE (2016)
Immune Cell and Other Noncardiomyocyte Regulation of Cardiac Hypertrophy and Remodeling
Ryan A. Frieler et al.
CIRCULATION (2015)
Innate Immunity and the Failing Heart The Cytokine Hypothesis Revisited
Douglas L. Mann
CIRCULATION RESEARCH (2015)
Mode of action of nintedanib in the treatment of idiopathic pulmonary fibrosis
Lutz Wollin et al.
EUROPEAN RESPIRATORY JOURNAL (2015)
Clinical relevance of right ventricular diastolic stiffness in pulmonary hypertension
Pia Trip et al.
EUROPEAN RESPIRATORY JOURNAL (2015)
CTGF knockout does not affect cardiac hypertrophy and fibrosis formation upon chronic pressure overload
Magda S. C. Fontes et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Carvedilol improves biventricular fibrosis and function in experimental pulmonary hypertension
Kenichi Okumura et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2015)
Cardiac fibroblasts: from development to heart failure
Thomas Moore-Morris et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2015)
Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling
Federica Accornero et al.
MOLECULAR AND CELLULAR BIOLOGY (2015)
The role of KCa3.1 channels in cardiac fibrosis induced by pressure overload in rats
Li-Mei Zhao et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2015)
Human umbilical cord blood-derived mononuclear cells improve murine ventricular function upon intramyocardial delivery in right ventricular chronic pressure overload
Saji Oommen et al.
STEM CELL RESEARCH & THERAPY (2015)
5-HT2B Receptor Antagonists Inhibit Fibrosis and Protect from RV Heart Failure
Wiebke Janssen et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Iloprost reverses established fibrosis in experimental right ventricular failure
Jose Gomez-Arroyo et al.
EUROPEAN RESPIRATORY JOURNAL (2015)
Modulation of angiotensin II signaling in the prevention of fibrosis
Amanda M. Murphy et al.
FIBROGENESIS & TISSUE REPAIR (2015)
Detection of elevated right ventricular extracellular volume in pulmonary hypertension using Accelerated and Navigator-Gated Look-Locker Imaging for Cardiac T1 Estimation (ANGIE) cardiovascular magnetic resonance
Bhairav B. Mehta et al.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE (2015)
Sildenafil treatment in established right ventricular dysfunction improves diastolic function and attenuates interstitial fibrosis independent from afterload
Marinus A. Borgdorff et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)
Direct and indirect protection of right ventricular function by estrogen in an experimental model of pulmonary arterial hypertension
Aiping Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)
Pulmonary hypertension in patients with advanced heart failure is associated with increased levels of interleukin-6
Jure Dolenc et al.
BIOMARKERS (2014)
Integrins αvβ5 and αvβ3 promote latent TGF-β1 activation by human cardiac fibroblast contraction
Vincent Sarrazy et al.
CARDIOVASCULAR RESEARCH (2014)
Developmental Heterogeneity of Cardiac Fibroblasts Does Not Predict Pathological Proliferation and Activation
Shah R. Ali et al.
CIRCULATION RESEARCH (2014)
The Right Ventricle in Pulmonary Arterial Hypertension Disorders of Metabolism, Angiogenesis and Adrenergic Signaling in Right Ventricular Failure
John J. Ryan et al.
CIRCULATION RESEARCH (2014)
Wnt and the Wnt signaling pathway in bone development and disease
Yiping Wang et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2014)
Inhibition of the Ca2+-sensing receptor rescues pulmonary hypertension in rats and mice
Qiang Guo et al.
HYPERTENSION RESEARCH (2014)
Antifibrotic Effects of Noscapine through Activation of Prostaglandin E2 Receptors and Protein Kinase A
Jacob Kach et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis
Thomas Moore-Morris et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
The profibrotic role of endothelin-1: Is the door still open for the treatment of fibrotic diseases?
Fernando Rodriguez-Pascual et al.
LIFE SCIENCES (2014)
c-kit+ cells minimally contribute cardiomyocytes to the heart
Jop H. van Berlo et al.
NATURE (2014)
Dehydroepiandrosterone restores right ventricular structure and function in rats with severe pulmonary arterial hypertension
Abdallah Alzoubi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Platelet-derived growth factor-D promotes fibrogenesis of cardiac fibroblasts
Tieqiang Zhao et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2013)
Mineralocorticoid receptor antagonism attenuates experimental pulmonary hypertension
Ioana R. Preston et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Diminazene Attenuates Pulmonary Hypertension and Improves Angiogenic Progenitor Cell Functions in Experimental Models
Vinayak Shenoy et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2013)
Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling
Baktybek Kojonazarov et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
CCN2/CTGF attenuates myocardial hypertrophy and cardiac dysfunction upon chronic pressure-overload
Jorgen Gravning et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2013)
FK506 activates BMPR2 rescues endothelial dysfunction, and reverses pulmonary hypertension
Edda Spiekerkoetter et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
IL-1 Induces Proinflammatory Leukocyte Infiltration and Regulates Fibroblast Phenotype in the Infarcted Myocardium
Amit Saxena et al.
JOURNAL OF IMMUNOLOGY (2013)
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
Kate M. Herum et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2013)
Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential
Kristin Dawson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2013)
Myofibroblast-mediated mechanisms of pathological remodelling of the heart
Karl T. Weber et al.
NATURE REVIEWS CARDIOLOGY (2013)
Time course of right ventricular pressure-overload induced myocardial fibrosis: relationship to changes in fibroblast postsynthetic procollagen processing
Catalin F. Baicu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2012)
The monocrotaline model of pulmonary hypertension in perspective
Jose G. Gomez-Arroyo et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
Dysregulated Renin-Angiotensin-Aldosterone System Contributes to Pulmonary Arterial Hypertension
Frances S. de Man et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2012)
Bisoprolol Delays Progression Towards Right Heart Failure in Experimental Pulmonary Hypertension
Frances S. de Man et al.
CIRCULATION-HEART FAILURE (2012)
Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle
Marinus A. J. Borgdorff et al.
EUROPEAN JOURNAL OF HEART FAILURE (2012)
Chemokines regulate small leucine-rich proteoglycans in the extracellular matrix of the pressure-overloaded right ventricle
Anne Waehre et al.
JOURNAL OF APPLIED PHYSIOLOGY (2012)
Therapeutic inhibition of fatty acid oxidation in right ventricular hypertrophy: exploiting Randle's cycle
Yong-Hu Fang et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
Activation of canonical Wnt signalling is required for TGF-β-mediated fibrosis
Alfiya Akhmetshina et al.
NATURE COMMUNICATIONS (2012)
CTGF is a central mediator of tissue remodeling and fibrosis and its inhibition can reverse the process of fibrosis
Kenneth E. Lipson et al.
FIBROGENESIS & TISSUE REPAIR (2012)
Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension
Benjamin H. Freed et al.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE (2012)
Suppression of Histone Deacetylases Worsens Right Ventricular Dysfunction after Pulmonary Artery Banding in Rats
Harm J. Bogaard et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
TNF-α increases cardiac fibroblast lysyl oxidase expression through TGF-β and PI3Kinase signaling pathways
Tetyana G. Voloshenyuk et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
Fibroblasts and Myofibroblasts: What Are We Talking About?
Jennifer Baum et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2011)
ACE2 Improves Right Ventricular Function in a Pressure Overload Model
Jennifer A. Johnson et al.
PLOS ONE (2011)
Antioxidant treatment attenuates pulmonary arterial hypertension-induced heart failure
Everaldo M. Redout et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Adrenergic Receptor Blockade Reverses Right Heart Remodeling and Dysfunction in Pulmonary Hypertensive Rats
Harm J. Bogaard et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2010)
Transmembrane Signaling Proteoglycans
John R. Couchman
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 26 (2010)
Active Wnt signaling in response to cardiac injury
Martinus I. F. J. Oerlemans et al.
BASIC RESEARCH IN CARDIOLOGY (2010)
Angiotensin-Converting Enzyme 2 Suppresses Pathological Hypertrophy, Myocardial Fibrosis, and Cardiac Dysfunction
JiuChang Zhong et al.
CIRCULATION (2010)
Inflammation in right ventricular dysfunction due to thromboembolic pulmonary hypertension
Stephan von Haehling et al.
INTERNATIONAL JOURNAL OF CARDIOLOGY (2010)
Cardiac mast cells cause atrial fibrillation through PDGF-A-mediated fibrosis in pressure-overloaded mouse hearts
Chien-hui Liao et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
The Right Ventricle and Pulmonary Circulation: Basic Concepts
Clifford R. Greyson
REVISTA ESPANOLA DE CARDIOLOGIA (2010)
Wnt signal transduction pathways
Yuko Komiya et al.
Organogenesis (2010)
Chronic Pulmonary Artery Pressure Elevation Is Insufficient to Explain Right Heart Failure
Harm J. Bogaard et al.
CIRCULATION (2009)
WISP1, a Pro-mitogenic, Pro-survival Factor, Mediates Tumor Necrosis Factor-α (TNF-α)-stimulated Cardiac Fibroblast Proliferation but Inhibits TNF-α-induced Cardiomyocyte Death
Kaliyamurthi Venkatachalam et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
A myocardial lineage derives from Tbx18 epicardial cells
Chen-Leng Cai et al.
NATURE (2008)
Pulmonary embolism causes endomyocarditis in the human heart
M. P. V. Begieneman et al.
HEART (2008)
The role of TGF-β signaling in myocardial infarction and cardiac remodeling
Marcin Bujak et al.
CARDIOVASCULAR RESEARCH (2007)
IL-1β stimulates rat cardiac fibroblast migration via MAP kinase pathways
M. Darren Mitchell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice
Sandra B. Haudek et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Extracellular matrix proteins and matrix metalloproteinases differ between various right and left ventricular sites in end-stage cardiomyopathies
E Herpel et al.
VIRCHOWS ARCHIV (2005)
Intracardiac basic fibroblast growth factor and transforming growth factor-beta 1 mRNA and their proteins expression level in patients with pressure or volume-overload right or left ventricular hypertrophy
ZY He et al.
ACTA CARDIOLOGICA (2005)
TGF-β signaling and the fibrotic response
A Leask et al.
FASEB JOURNAL (2004)
Transforming growth factor-β induces endothelin-1 expression through activation of the smad signaling pathway
F Rodríguez-Pascual et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2004)
Profibrotic effects of endothelin-1 via the ETA receptor in cultured human cardiac fibroblasts
S Hafizi et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2004)
Right ventricular damage due to pulmonary embolism: examination of the number of infiltrating macrophages
K Iwadate et al.
FORENSIC SCIENCE INTERNATIONAL (2003)
Tumor necrosis factor-α-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis
JF Peng et al.
CIRCULATION RESEARCH (2002)
β-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases
J Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cardiac fibrosis as a cause of diastolic dysfunction
BS Burlew et al.
HERZ (2002)
Receptor signaling and structure: insights from serotonin-1 receptors
PR Albert et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2001)
β-adrenergic stimulation of rat cardiac fibroblasts promotes protein synthesis via the activation of phosphatidylinositol 3-kinase
F Colombo et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2001)
Identification of novel TGF-β/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach
F Verrecchia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Tie2-Cre transgenic mice:: A new model for endothelial cell-lineage analysis in vivo
YY Kisanuki et al.
DEVELOPMENTAL BIOLOGY (2001)
Myofibroblasts in reperfused myocardial infarcts express the embryonic form of smooth muscle myosin heavy chain (SMemb)
NG Frangogiannis et al.
CARDIOVASCULAR RESEARCH (2000)