4.7 Article

Resistant risk and resistance-related point mutation in SdhC1 of pydiflumetofen in Fusarium pseudograminearum

Related references

Note: Only part of the references are listed.
Article Agriculture, Multidisciplinary

Resistance Risk and Resistance-Related Point Mutation in SdhB and SdhC1 of Cyclobutrifluram in Fusarium pseudograminearum

Yiwen Li et al.

Summary: Cyclobutrifluram is a novel succinate dehydrogenase inhibitor (SDHI) developed by Syngenta that inhibits Fusarium pseudograminearum. The resistance risk of F. pseudograminearum to cyclobutrifluram was evaluated, and five resistant mutants were generated through fungicide adaption. These mutants showed resistance to pydiflumetofen but sensitivity to other fungicides. Point mutations in FpSdhB and FpSdhC were found in the cyclobutrifluram-resistant mutants, and overexpression transformation assays confirmed their role in conferring resistance.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2023)

Article Agriculture, Multidisciplinary

Multiple Mutations in SDHB and SDHC2 Subunits Confer Resistance to the Succinate Dehydrogenase Inhibitor Cyclobutrifluram in Fusarium fujikuroi

Zhaolin Xue et al.

Summary: Fusarium fujikuroi, a dominant phytopathogenic fungus causing rice bakanae disease, is shown to be inhibited by the novel succinate dehydrogenase inhibitor cyclobutrifluram. Mutations in FfSdhB (H248L/Y) and FfSdhC2 (G80R or A83V) were found to confer resistance to cyclobutrifluram in F. fujikuroi, leading to decreased affinity between the drug and FfSdhs.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2023)

Article Agronomy

Fusarium graminearum FgSdhC1 point mutation A78V confers resistance to the succinate dehydrogenase inhibitor pydiflumetofen

Wenyong Shao et al.

Summary: This study reported the field resistance of Fg to pydiflumetofen for the first time and confirmed that the point mutation FgSdhC1(A78V) confers resistance of Fg to pydiflumetofen. The study provides critical information for monitoring and managing pydiflumetofen resistance in Fg.

PEST MANAGEMENT SCIENCE (2022)

Article Plant Sciences

Transcriptome Analysis and Functional Validation Identify a Putative bZIP Transcription Factor, Fpkapc, that Regulates Development, Stress Responses, and Virulence in Fusarium pseudograminearum

Jingya Zhao et al.

Summary: In this study, a bZIP transcription factor Fpkapc was identified in Fusarium pseudograminearum and shown to play multiple roles in governing growth, development, stress responses, and virulence in the pathogen.

PHYTOPATHOLOGY (2022)

Article Plant Sciences

Baseline Sensitivity and Potential Resistance Mechanisms for Fusarium pseudograminearum to Fludioxonil

Feng Zhou et al.

Summary: Fusarium crown rot (FCR), caused by Fusarium pseudograminearum, is a significant disease in wheat production in the Huanghuai wheat-growing region of China. Fludioxonil, a phenylpyrrole fungicide, has not been registered for FCR control in China. This study identified four fludioxonil-resistant mutants of F. pseudograminearum and found that they exhibited reduced growth, sporulation, and pathogenicity. Molecular analysis showed that these mutants did not possess the characteristic amino acid changes associated with fludioxonil resistance in other species. The study also revealed cross-resistance between fludioxonil and cyprodinil, tebuconazole, and difenoconazole.

PLANT DISEASE (2022)

Article Microbiology

Control efficiency of hexaconazole-lentinan against wheat sharp eyespot and wheat crown rot and the associated effects on rhizosphere soil fungal community

Xiu Yang et al.

Summary: The use of polysaccharides to induce systemic immune response in plants is an effective method for disease resistance. This study evaluated the control effects of hexaconazole and lentinan seed dressing on two wheat diseases, and discussed their effects on plant growth, soil enzyme activity, and fungal community diversity in the wheat rhizosphere. The results showed that the combined seed dressing of hexaconazole and lentinan significantly improved the control effect of the diseases without affecting soil enzyme activities. Different seed dressing treatments also altered the fungal community structure in the wheat rhizosphere soil.

FRONTIERS IN MICROBIOLOGY (2022)

Article Agronomy

Resistance risk assessment for a novel succinate dehydrogenase inhibitor pydiflumetofen inFusarium asiaticum

Wenchan Chen et al.

Summary: The study identified a moderate to high resistance risk of F. asiaticum to pydiflumetofen, with resistant mutants showing no fitness penalty in terms of growth, conidiation, and virulence. Cross-resistance between different SDHIs was detected in the resistant mutants.

PEST MANAGEMENT SCIENCE (2021)

Article Agriculture, Multidisciplinary

Point Mutations in FgSdhC2 or in the 5′ Untranslated Region of FgSdhC1 Confer Resistance to a Novel Succinate Dehydrogenase Inhibitor Flubeneteram in Fusarium graminearum

Wenchan Chen et al.

Summary: This study generated four Flu-resistant mutants of Fusarium graminearum through fungicide domestication, and found three resistant genotypes with mutations in FgSdh. Genotype I had a mutation in the 5' UTR of FgSdhC(1), while genotypes II and III had mutations in FgSdhC(2) conferring different levels of resistance.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2021)

Article Plant Sciences

Contamination and Translocation of Deoxynivalenol and Its Derivatives Associated with Fusarium Crown Rot of Wheat in Northern China

Xuefeng Fan et al.

Summary: Fusarium crown rot (FCR) is a significant wheat disease in northern China, caused by Fusarium pseudograminearum which produces mycotoxins. The severity of FCR affects the distribution of trichothecenes in different wheat tissues, with variations influenced by factors such as climate, irrigation, and fungicide application. Higher levels of mycotoxin were observed in wheat plants under field conditions, posing a threat to feed production.

PLANT DISEASE (2021)

Article Biochemistry & Molecular Biology

Activity of a SDHI fungicide penflufen and the characterization of natural-resistance in Fusarium fujikuroi

Yanan Sun et al.

Summary: The novel succinate dehydrogenase inhibitor fungicide penflufen showed good bioactivity against F. fujikuroi but weak activity against other fungi, indicating its potential in controlling the disease. Natural resistance to penflufen was observed among F. fujikuroi isolates, with no cross-resistance to commonly used fungicides detected. Mutation analysis identified five different point mutations in resistant isolates, providing insights into possible resistance mechanisms.

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY (2021)

Article Multidisciplinary Sciences

Effects of Drought-Stress on Fusarium Crown Rot Development in Barley

Xinlun Liu et al.

PLOS ONE (2016)

Article Biochemistry & Molecular Biology

Upscaled CTAB-Based DNA Extraction and Real-Time PCR Assays for Fusarium culmorum and F. graminearum DNA in Plant Material with Reduced Sampling Error

Christoph Brandfass et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2008)