Journal
PATHOLOGY RESEARCH AND PRACTICE
Volume 246, Issue -, Pages -Publisher
ELSEVIER GMBH
DOI: 10.1016/j.prp.2023.154500
Keywords
Uterus; Placenta; Pregnancy; INSR; ALK; THBS1
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Uterine IMTs, which are rare tumors, have been found to have ALK rearrangements and ALK immunohistochemical expression. They are more commonly found in pregnancy and exhibit different characteristics compared to other uterine IMTs. This study reports a case of uterine IMT discovered during delivery, which is associated with a previously unreported THBS1-INSR fusion.
Uterine inflammatory myofibroblastic tumors (IMTs) are rare and, as in other localisations, they are associated with ALK rearrangements and ALK immunohistochemical expression. They are more frequently found during pregnancy, and in this context, they show different characteristics compared to other uterine IMTs. Here, we report the case of a uterine IMT discovered during delivery, and being associated with a previously unreported THBS1-INSR fusion.
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