Journal
PATHOLOGY RESEARCH AND PRACTICE
Volume 245, Issue -, Pages -Publisher
ELSEVIER GMBH
DOI: 10.1016/j.prp.2023.154451
Keywords
NCK1-AS1; LncRNA; Cancer; MicroRNAs
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NCK1-AS1 is a lncRNA that promotes carcinogenesis and has been verified in multiple types of cancer. It acts as a sponge for several microRNAs. In this review, we summarize the functions of NCK1-AS1 in malignant conditions and atherosclerosis.
NCK1 Antisense RNA 1 (NCK1-AS1), alternatively named as NCK1-DT, is a long non-coding RNA (lncRNA) with important roles in the carcinogenesis. Multiple studies verified its oncogenic role in different types of cancer, including gastric cancer, non-small cell lung cancer, glioma, prostate cancer and cervical cancer. NCK1-AS1 functions as a sponge for several microRNAs, including miR-137, miR-22-3p, miR-526b-5p, miR-512-5p, miR-138-2-3p and miR-6857. In this review we present an outline of NCK1-AS1 function in malignant conditions as well as atherosclerosis.
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