Journal
ORGANIC LETTERS
Volume 25, Issue 19, Pages 3553-3558Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.3c01197
Keywords
-
Categories
Ask authors/readers for more resources
An efficient metal-free, photoredox-mediated cascade cyclization of aryl 1-haloalk-5-ynyl ketones has been developed. Using catalytic amounts of eosin Y (EY) and EtNMe2 as a reductive quencher, various aryl 1-haloalk-5-ynyl ketones have been transformed into the corresponding cyclization products in up to 98% yield. As a result, synthetic access to differently alpha-functionalized cyclopenta[b]naphthones and direct construction of cyclopenta[b]naphtholes has been developed.
An efficient metal-free, photoredox-mediated cascade cyclization of aryl 1-haloalk-5-ynyl ketones has been developed. Using catalytic amounts of eosin Y (EY) and EtNMe2 as a reductive quencher, various aryl 1-haloalk-5-ynyl ketones have been transformed into the corresponding cyclization products in up to 98% yield. As a result, synthetic access to differently alpha-functionalized cyclopenta[b]naphthones and direct construction of cyclopenta[b]naphtholes has been developed.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available