A Cheap and Efficient Oxidant (n-Bu)4NNO3-Enabled C(sp2)- and C(sp3)-H Olefination at Room Temperature

To further promote the widely practical application of C-H activation, developing green and mild reaction conditions has invariably been the objective of researchers, especially when it comes to remote C-H activation reactions. Herein, we report a new cheap and powerful (n-Bu)4NNO3 oxidant. This oxidant is efficient and universal for Pd(II)catalyzed sp2 and sp3 C-H olefination and allows the reaction to be carried out at room temperature. Because of this, we attempted to make C-H functionalization more economical and environmentally benign.

Automated summary

To further promote the practical application of C-H activation, researchers aim to develop green and mild reaction conditions, especially for remote C-H activation reactions. In this study, a new cheap and powerful (n-Bu)4NNO3 oxidant was reported, which enables Pd(II) catalyzed sp2 and sp3 C-H olefination at room temperature. This advancement contributes to making C-H functionalization more economical and environmentally benign.