Transfection reflections: fit-for-purpose delivery of nucleic acids

Transfection is a foundational technology in biosciences, biotechnology, and the development of biotherapeutic agents. Given its transcendence, it is problematic that transfection remains a poorly understood and insufficiently characterized endeavour. Here we state the case for the urgent reworking of transfection as a fit-for-purpose technological foundation for the ambitions of scientists and engineers.

Automated summary

Transfection is a fundamental technology in biosciences and biotechnology, but its understanding and characterization are inadequate. Therefore, we emphasize the urgent need for the significant improvement of transfection to meet the ambitions of scientists and engineers.