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Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
Jennifer G. DeLuca et al.
CELL (2006)
ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division
Beth A. Rasala et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A new method reveals microtubule minus ends throughout the meiotic spindle
Kendra S. Burbank et al.
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The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly
Arturo V. Orjalo et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner
Vladimir Varga et al.
NATURE CELL BIOLOGY (2006)
Kinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cells
LA Cameron et al.
JOURNAL OF CELL BIOLOGY (2006)
HURP is part of a ran-dependent complex involved in spindle formation
MD Koffa et al.
CURRENT BIOLOGY (2006)
HURP is a ran-importin β-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes
HHW Silljé et al.
CURRENT BIOLOGY (2006)
Analysis of a RanGTP-regulated gradient in mitotic somatic cells
P Kaláb et al.
NATURE (2006)
Molecular requirements for kinetochore-associated microtubule formation in mammalian cells
US Tulu et al.
CURRENT BIOLOGY (2006)
NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
L Haren et al.
JOURNAL OF CELL BIOLOGY (2006)
GCP-WD is a γ-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation
J Lüders et al.
NATURE CELL BIOLOGY (2006)
Efficient mitosis in human cells lacking poleward microtubule flux
NJ Ganem et al.
CURRENT BIOLOGY (2005)
Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins
G Goshima et al.
JOURNAL OF CELL BIOLOGY (2005)
The extracellular matrix guides the orientation of the cell division axis
M Théry et al.
NATURE CELL BIOLOGY (2005)
Microtubule movements on the arms of mitotic chromosomes:: Polar ejection forces quantified in vitro
GJ Brouhard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles
TJ Mitchison et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Efficient chromosome capture requires a bias in the 'search-and-capture' process during mitotic-spindle assembly
R Wollman et al.
CURRENT BIOLOGY (2005)
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
LC Kapitein et al.
NATURE (2005)
Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres
H Maiato et al.
NATURE CELL BIOLOGY (2005)
Stathmin-tubulin interaction gradients in motile and mitotic cells
P Niethammer et al.
SCIENCE (2004)
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity
WJ Lan et al.
CURRENT BIOLOGY (2004)
Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase
GC Rogers et al.
NATURE (2004)
Mitosis-specific anchoring of γ tubulin complexes by pericentrin controls spindle organization and mitotic entry
WC Zimmerman et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis
H Maiato et al.
JOURNAL OF CELL BIOLOGY (2004)
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles
DT Miyamoto et al.
JOURNAL OF CELL BIOLOGY (2004)
Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts
S Brunet et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly
SC Sampath et al.
CELL (2004)
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle
R Gassmann et al.
JOURNAL OF CELL BIOLOGY (2004)
Contribution of noncentrosomal microtubules to spindle assembly in Drosophila spermatocytes
E Rebollo et al.
PLOS BIOLOGY (2004)
Mammalian pins is a conformational switch that links NuMA to heterotrimeric G proteins
QS Du et al.
CELL (2004)
Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by aurora B-dependent phosphorylation
R Ohi et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles:: implications for spindle mechanics
P Maddox et al.
JOURNAL OF CELL BIOLOGY (2003)
Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo
M Gotta et al.
CURRENT BIOLOGY (2003)
Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis
A Khodjakov et al.
JOURNAL OF CELL BIOLOGY (2003)
PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone
C Mollinari et al.
JOURNAL OF CELL BIOLOGY (2002)
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
P Kalab et al.
SCIENCE (2002)
Organized microtubule arrays in γ-tubulin-depleted Drosophila spermatocytes
P Sampaio et al.
CURRENT BIOLOGY (2001)
Physical properties determining self-organization of motors and microtubules
T Surrey et al.
SCIENCE (2001)
Role of importin-β in coupling ran to downstream targets in microtubule assembly
C Wiese et al.
SCIENCE (2001)
Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity
OJ Gruss et al.
CELL (2001)
Importin β is a mitotic target of the small GTPase ran in spindle assembly
MV Nachury et al.
CELL (2001)
Xkid, a chromokinesin required for chromosome alignment on the metaphase plate
C Antonio et al.
CELL (2000)
The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement
H Funabiki et al.
CELL (2000)
Formation of spindle poles by dynein/dynactin-dependent transport of NuMA
A Merdes et al.
JOURNAL OF CELL BIOLOGY (2000)
Centrosome-independent mitotic spindle formation in vertebrates
A Khodjakov et al.
CURRENT BIOLOGY (2000)
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