Related references
Note: Only part of the references are listed.Optogenetic EB1 inactivation shortens metaphase spindles by disrupting cortical force-producing interactions with astral microtubules
Alessandro Dema et al.
CURRENT BIOLOGY (2022)
Naegleria's mitotic spindles are built from unique tubulins and highlight core spindle features
Katrina B. Velle et al.
CURRENT BIOLOGY (2022)
Non-centrosomal microtubules at kinetochores promote rapid chromosome biorientation during mitosis in human cells
Fioranna Renda et al.
CURRENT BIOLOGY (2022)
On the role of phase separation in the biogenesis of membraneless compartments
Andrea Musacchio
EMBO JOURNAL (2022)
NuMA forms condensates through phase separation to drive spindle pole assembly
Huixian Ma et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2022)
The chirality of the mitotic spindle provides a mechanical response to forces and depends on microtubule motors and augmin
Monika Trupinic et al.
CURRENT BIOLOGY (2022)
Reconstitution and mechanistic dissection of the human microtubule branching machinery
Yaqian Zhang et al.
JOURNAL OF CELL BIOLOGY (2022)
Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals
Ana C. Almeida et al.
CELL REPORTS (2022)
The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)
Michael J. Rale et al.
ELIFE (2022)
Three-dimensional structure of kinetochore-fibers in human mitotic spindles
Robert Kiewisz et al.
ELIFE (2022)
Genetic Control of Kinetochore-Driven Microtubule Growth in Drosophila Mitosis
Julia Popova et al.
CELLS (2022)
Ran-GTP Is Non-essential to Activate NuMA for Mitotic Spindle-Pole Focusing but Dynamically Polarizes HURP Near Chromosomes
Kenta Tsuchiya et al.
CURRENT BIOLOGY (2021)
Kinetochore life histories reveal an Aurora-B-dependent error correction mechanism in anaphase (vol 56, pg 3082.e1, 2021)
Onur Sen et al.
DEVELOPMENTAL CELL (2021)
Opposing motors provide mechanical and functional robustness in the human spindle
Lila Neahring et al.
DEVELOPMENTAL CELL (2021)
Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependei it forces
Mihaela Jagric et al.
ELIFE (2021)
The structure of the γ-TuRC: a 25-years-old molecular puzzle
Erik Zupa et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2021)
K-fiber bundles in the mitotic spindle are mechanically reinforced by Kif15
Marcus A. Begley et al.
MOLECULAR BIOLOGY OF THE CELL (2021)
A hydrodynamic instability drives protein droplet formation on microtubules to nucleate branches
Sagar U. Setru et al.
NATURE PHYSICS (2021)
NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation
Mengjie Sun et al.
NATURE COMMUNICATIONS (2021)
CYK4 relaxes the bias in the off-axis motion by MKLP1 kinesin-6
Yohei Maruyama et al.
COMMUNICATIONS BIOLOGY (2021)
The Xenopus spindle is as dense as the surrounding cytoplasm
Abin Biswas et al.
DEVELOPMENTAL CELL (2021)
Tension promotes kinetochore-microtubule release by Aurora B kinase
Geng-Yuan Chen et al.
JOURNAL OF CELL BIOLOGY (2021)
Molecular insight into how γ-TuRC makes microtubules
Akanksha Thawani et al.
JOURNAL OF CELL SCIENCE (2021)
Spindle positioning and its impact on vertebrate tissue architecture and cell fate
Terry Lechler et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
Regulation of microtubule dynamics, mechanics and function through the growing tip
Nikita B. Gudimchuk et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2021)
NuMA assemblies organize microtubule asters to establish spindle bipolarity in acentrosomal human cells
Takumi Chinen et al.
EMBO JOURNAL (2020)
CLASP2 binding to curved microtubule tips promotes flux and stabilizes kinetochore attachments
Hugo Girao et al.
JOURNAL OF CELL BIOLOGY (2020)
Asymmetric Molecular Architecture of the Human γ-Tubulin Ring Complex
Michal Wieczorek et al.
CELL (2020)
Electron tomography reveals aspects of spindle structure important for mechanical stability at metaphase
Eileen O'Toole et al.
MOLECULAR BIOLOGY OF THE CELL (2020)
Insights into the assembly and activation of the microtubule nucleator γ-TuRC
Peng Liu et al.
NATURE (2020)
Phase separation of TPX2 enhances and spatially coordinates microtubule nucleation
Matthew R. King et al.
NATURE COMMUNICATIONS (2020)
In vitro reconstitution of branching microtubule nucleation
Ammarah Tariq et al.
ELIFE (2020)
Biochemical reconstitution of branching microtubule nucleation
Raymundo Alfaro-Aco et al.
ELIFE (2020)
Microtubule Nucleation Properties of Single Human gamma TuRCs Explained by Their Cryo-EM Structure
Tanja Consolati et al.
DEVELOPMENTAL CELL (2020)
Individual kinetochore-fibers locally dissipate force to maintain robust mammalian spindle structure
Alexandra F. Long et al.
JOURNAL OF CELL BIOLOGY (2020)
Collective effects of XMAP215, EB1, CLASP2, and MCAK lead to robust microtubule treadmilling
Goker Arpag et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Mechanisms generating cancer genome complexity from a single cell division error
Neil T. Umbreit et al.
SCIENCE (2020)
Organizational Principles of the NuMA-Dynein Interaction Interface and Implications for Mitotic Spindle Functions
Cristina Renna et al.
STRUCTURE (2020)
Kinesin-14 motors drive a right-handed helical motion of antiparallel microtubules around each other
Aniruddha Mitra et al.
NATURE COMMUNICATIONS (2020)
Microneedle manipulation of the mammalian spindle reveals specialized, short-lived reinforcement near chromosomes
Pooja Suresh et al.
ELIFE (2020)
The Mitotic Crosslinking Protein PRC1 Acts Like a Mechanical Dashpot to Resist Microtubule Sliding
Ignas Gaska et al.
DEVELOPMENTAL CELL (2020)
The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy
Akanksha Thawani et al.
ELIFE (2020)
XMAP215 and γ-tubulin additively promote microtubule nucleation in purified solutions
Brianna R. King et al.
MOLECULAR BIOLOGY OF THE CELL (2020)
Microtubules Enhance Mesoscale Effective Diffusivity in the Crowded Metaphase Cytoplasm
Lina Carlini et al.
DEVELOPMENTAL CELL (2020)
Microtubule poleward flux in human cells is driven by the coordinated action of four kinesins
Yulia Steblyanko et al.
EMBO JOURNAL (2020)
Active forces shape the metaphase spindle through a mechanical
David Oriola et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Spindle Scaling Is Governed by Cell Boundary Regulation of Microtubule Nucleation
Elisa Maria Rieckhoff et al.
CURRENT BIOLOGY (2020)
Microtubule End-Clustering Maintains a Steady-State Spindle Shape
Christina L. Hueschen et al.
CURRENT BIOLOGY (2019)
The microtubule-associated protein EML3 regulates mitotic spindle assembly by recruiting the Augmin complex to spindle microtubules
Jia Luo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Mechanically Distinct Microtubule Arrays Determine the Length and Force Response of the Meiotic Spindle
Jun Takagi et al.
DEVELOPMENTAL CELL (2019)
Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth
Ana F. David et al.
JOURNAL OF CELL BIOLOGY (2019)
Spatiotemporal organization of branched microtubule networks
Akanksha Thawani et al.
ELIFE (2019)
Self-Organization of Minimal Anaphase Spindle Midzone Bundles
Jonathon Hannabuss et al.
CURRENT BIOLOGY (2019)
Direct observation of branching MT nucleation in living animal cells
Vikash Verma et al.
JOURNAL OF CELL BIOLOGY (2019)
High-resolution imaging reveals how the spindle midzone impacts chromosome movement
Melissa C. Pamula et al.
JOURNAL OF CELL BIOLOGY (2019)
A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes
Chun So et al.
SCIENCE (2019)
The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex
Prasad Trivedi et al.
NATURE CELL BIOLOGY (2019)
Cargo adaptors regulate stepping and force generation of mammalian dynein-dynactin
Mohamed M. Elshenawy et al.
NATURE CHEMICAL BIOLOGY (2019)
Kif2a Scales Meiotic Spindle Size in Hymenochirus boettgeri
Kelly E. Miller et al.
CURRENT BIOLOGY (2019)
Spindle-Length-Dependent HURP Localization Allows Centrosomes to Control Kinetochore-Fiber Plus-End Dynamics
Damian Dudka et al.
CURRENT BIOLOGY (2019)
The mammalian kinetochore-microtubule interface: robust mechanics and computation with many microtubules
Alexandra F. Long et al.
CURRENT OPINION IN CELL BIOLOGY (2019)
Soluble tubulin is significantly enriched at mitotic centrosomes
Johannes Baumgart et al.
JOURNAL OF CELL BIOLOGY (2019)
Chromosome Segregation Is Biased by Kinetochore Size
Danica Drpic et al.
CURRENT BIOLOGY (2018)
The XMAP215 Ortholog Alp14 Promotes Microtubule Nucleation in Fission Yeast
Ignacio Flor-Parra et al.
CURRENT BIOLOGY (2018)
Cooperative Accumulation of Dynein-Dynactin at Microtubule Minus-Ends Drives Microtubule Network Reorganization
Ruensern Tan et al.
DEVELOPMENTAL CELL (2018)
Microtubules assemble near most kinetochores during early prometaphase in human cells
Vitali Sikirzhytski et al.
JOURNAL OF CELL BIOLOGY (2018)
Mechanism of how augmin directly targets the gamma-tubulin ring complex to microtubules
Jae-Geun Song et al.
JOURNAL OF CELL BIOLOGY (2018)
In vivo mitotic spindle scaling can be modulated by changing the levels of a single protein: the microtubule polymerase XMAP215
Ana Milunovic-Jevtic et al.
MOLECULAR BIOLOGY OF THE CELL (2018)
XMAP215 is a microtubule nucleation factor that functions synergistically with the γ-tubulin ring complex
Akanksha Thawani et al.
NATURE CELL BIOLOGY (2018)
Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis
Carlos Sacristan et al.
NATURE CELL BIOLOGY (2018)
Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble
Masako Okumura et al.
ELIFE (2018)
Autocatalytic microtubule nucleation determines the size and mass of Xenopus laevis egg extract spindles
Franziska Decker et al.
ELIFE (2018)
Chromosome Segregation Fidelity in Epithelia Requires Tissue Architecture
Kristin A. Knouse et al.
CELL (2018)
The mitotic spindle is chiral due to torques within microtubule bundles
Maja Novak et al.
NATURE COMMUNICATIONS (2018)
Optogenetic dissection of mitotic spindle positioning in vivo
Lars-Eric Fielmich et al.
ELIFE (2018)
The microtubule polymerase Stu2 promotes oligomerization of the γ-TuSC for cytoplasmic microtubule nucleation
Judith Gunzelmann et al.
ELIFE (2018)
Determinants of Polar versus Nematic Organization in Networks of Dynamic Microtubules and Mitotic Motors
Johanna Roostalu et al.
CELL (2018)
Geometry of antiparallel microtubule bundles regulates relative sliding and stalling by PRC1 and Kif4A
Sithara Wijeratne et al.
ELIFE (2018)
PRC1-labeled microtubule bundles and kinetochore pairs show one-to-one association in metaphase
Bruno Polak et al.
EMBO REPORTS (2017)
Mitotic spindle assembly in animal cells: a fine balancing act
Suzanna L. Prosser et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
NuMA recruits dynein activity to microtubule minus-ends at mitosis
Christina L. Hueschen et al.
ELIFE (2017)
Collective Force Regulation in Anti-parallel Microtubule Gliding by Dimeric Kif15 Kinesin Motors
Dana N. Reinemann et al.
CURRENT BIOLOGY (2017)
Mapping Load-Bearing in the Mammalian Spindle Reveals Local Kinetochore Fiber Anchorage that Provides Mechanical Isolation and Redundancy
Mary Williard Elting et al.
CURRENT BIOLOGY (2017)
The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin
Jeffrey B. Woodruff et al.
CELL (2017)
Large-Scale Analysis of CRISPR/Cas9 Cell-Cycle Knockouts Reveals the Diversity of p53-Dependent Responses to Cell-Cycle Defects
Kara L. McKinley et al.
DEVELOPMENTAL CELL (2017)
The Consequences of Chromosome Segregation Errors in Mitosis and Meiosis
Tamara Potapova et al.
BIOLOGY-BASEL (2017)
A TOG Protein Confers Tension Sensitivity to Kinetochore-Microtubule Attachments
Matthew P. Miller et al.
CELL (2016)
Regulation of mitotic spindle orientation: an integrated view
Florencia di Pietro et al.
EMBO REPORTS (2016)
Kinesin-5 inhibitor resistance is driven by kinesin-12
Emma G. Sturgill et al.
JOURNAL OF CELL BIOLOGY (2016)
Assembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1
Ian D. Wolff et al.
MOLECULAR BIOLOGY OF THE CELL (2016)
Working stroke of the kinesin-14, ncd, comprises two substeps of different direction
Bert Nitzsche et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
A force-generating machinery maintains the spindle at the cell center during mitosis
Carlos Garzon-Coral et al.
SCIENCE (2016)
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores
Janko Kajtez et al.
NATURE COMMUNICATIONS (2016)
The Augmin Connection in the Geometry of Microtubule Networks
Carlos Sanchez-Huertas et al.
CURRENT BIOLOGY (2015)
A Comparative Analysis of Spindle Morphometrics across Metazoans
Marina E. Crowder et al.
CURRENT BIOLOGY (2015)
Three-dimensional tracking of plus-tips by lattice light-sheet microscopy permits the quantification of microtubule growth trajectories within the mitotic apparatus
Norio Yamashita et al.
JOURNAL OF BIOMEDICAL OPTICS (2015)
Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components
David J. Wynne et al.
JOURNAL OF CELL BIOLOGY (2015)
Adaptive changes in the kinetochore architecture facilitate proper spindle assembly
Valentin Magidson et al.
NATURE CELL BIOLOGY (2015)
Complementary activities of TPX2 and chTOG constitute an efficient importin-regulated microtubule nucleation module
Johanna Roostalu et al.
NATURE CELL BIOLOGY (2015)
Short- and long-term effects of chromosome mis-segregation and aneuploidy
Stefano Santaguida et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
Ring closure activates yeast γTuRC for species-specific microtubule nucleation
Justin M. Kollman et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Microtubule detyrosination guides chromosomes during mitosis
Marin Barisic et al.
SCIENCE (2015)
Reversible centriole depletion with an inhibitor of Polo-like kinase 4
Yao Liang Wong et al.
SCIENCE (2015)
Ring closure activates yeast γTuRC for species-specific microtubule nucleation
Justin M. Kollman et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle
Faye M. Nixon et al.
ELIFE (2015)
Synergy between Multiple Microtubule-Generating Pathways Confers Robustness to Centrosome-Driven Mitotic Spindle Formation
Daniel Hayward et al.
DEVELOPMENTAL CELL (2014)
TPX2 levels modulate meiotic spindle size and architecture in Xenopus egg extracts
Kara J. Helmke et al.
JOURNAL OF CELL BIOLOGY (2014)
Direct kinetochore-spindle pole connections are not required for chromosome segregation
Vitali Sikirzhytski et al.
JOURNAL OF CELL BIOLOGY (2014)
Force on spindle microtubule minus ends moves chromosomes
Mary Williard Elting et al.
JOURNAL OF CELL BIOLOGY (2014)
NME7 is a functional component of the γ-tubulin ring complex
Pengfei Liu et al.
MOLECULAR BIOLOGY OF THE CELL (2014)
The Cep192-Organized Aurora A-Plk1 Cascade Is Essential for Centrosome Cycle and Bipolar Spindle Assembly
Vladimir Joukov et al.
MOLECULAR CELL (2014)
Reconstitution of the augmin complex provides insights into its architecture and function
Kuo-Chiang Hsia et al.
NATURE CELL BIOLOGY (2014)
The dynamics of microtubule minus ends in the human mitotic spindle
Nicolas Lecland et al.
NATURE CELL BIOLOGY (2014)
Physical basis of spindle self-organization
Jan Brugues et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Lattice light-sheet microscopy: Imaging molecules to embryos at high spatiotemporal resolution
Bi-Chang Chen et al.
SCIENCE (2014)
The nucleoporin MEL-28 promotes RanGTP-dependent γ-tubulin recruitment and microtubule nucleation in mitotic spindle formation
Hideki Yokoyama et al.
NATURE COMMUNICATIONS (2014)
Balanced Activity of Three Mitotic Motors Is Required for Bipolar Spindle Assembly and Chromosome Segregation
Roy G. H. P. van Heesbeen et al.
CELL REPORTS (2014)
The Kinesin-12 Kif15 is a processive track-switching tetramer
Hauke Drechsler et al.
ELIFE (2014)
Branching Microtubule Nucleation in Xenopus Egg Extracts Mediated by Augmin and TPX2
Sabine Petry et al.
CELL (2013)
Lateral to End-on Conversion of Chromosome-Microtubule Attachment Requires Kinesins CENP-E and MCAK
Roshan L. Shrestha et al.
CURRENT BIOLOGY (2013)
Kinesin-12 Differentially Affects Spindle Assembly Depending on Its Microtubule Substrate
Emma G. Sturgill et al.
CURRENT BIOLOGY (2013)
Loss of centrioles causes chromosomal instability in vertebrate somatic cells
Joo-Hee Sir et al.
JOURNAL OF CELL BIOLOGY (2013)
XMAP215 activity sets spindle length by controlling the total mass of spindle microtubules
Simone B. Reber et al.
NATURE CELL BIOLOGY (2013)
Genes involved in centrosome-independent mitotic spindle assembly in Drosophila S2 cells
Sara Moutinho-Pereira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Cytoplasmic Volume Modulates Spindle Size During Embryogenesis
Matthew C. Good et al.
SCIENCE (2013)
Changes in Cytoplasmic Volume Are Sufficient to Drive Spindle Scaling
James Hazel et al.
SCIENCE (2013)
Mitotic spindle scaling during Xenopus development by kif2a and importin α
Jeremy D. Wilbur et al.
ELIFE (2013)
The Highly Processive Kinesin-8, Kip3, Switches Microtubule Protofilaments with a Bias toward the Left
Volker Bormuth et al.
BIOPHYSICAL JOURNAL (2012)
Nucleation and Transport Organize Microtubules in Metaphase Spindles
Jan Brugues et al.
CELL (2012)
Organelle Growth Control through Limiting Pools of Cytoplasmic Components
Nathan W. Goehring et al.
CURRENT BIOLOGY (2012)
Nuclear envelope-associated dynein drives prophase centrosome separation and enables Eg5-independent bipolar spindle formation
Jonne A. Raaijmakers et al.
EMBO JOURNAL (2012)
The transition from meiotic to mitotic spindle assembly is gradual during early mammalian development
Aurelien Courtois et al.
JOURNAL OF CELL BIOLOGY (2012)
Human chromokinesins promote chromosome congression and spindle microtubule dynamics during mitosis
Cornelia Wandke et al.
JOURNAL OF CELL BIOLOGY (2012)
Katanin Contributes to Interspecies Spindle Length Scaling in Xenopus
Rose Loughlin et al.
CELL (2011)
Insights into the Micromechanical Properties of the Metaphase Spindle
Yuta Shimamoto et al.
CELL (2011)
The Spatial Arrangement of Chromosomes during Prometaphase Facilitates Spindle Assembly
Valentin Magidson et al.
CELL (2011)
Mechanisms of plant spindle formation
Han Zhang et al.
CHROMOSOME RESEARCH (2011)
A Complex of Kit18b and MCAK Promotes Microtubule Depolymerization and Is Negatively Regulated by Aurora Kinases
Marvin E. Tanenbaum et al.
CURRENT BIOLOGY (2011)
Amphiastral Mitotic Spindle Assembly in Vertebrate Cells Lacking Centrosomes
Jessica E. Hornick et al.
CURRENT BIOLOGY (2011)
A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging
Daniel G. Booth et al.
EMBO JOURNAL (2011)
PLK1 phosphorylation of pericentrin initiates centrosome maturation at the onset of mitosis
Kwanwoo Lee et al.
JOURNAL OF CELL BIOLOGY (2011)
A Tethering Mechanism Controls the Processivity and Kinetochore-Microtubule Plus-End Enrichment of the Kinesin-8 Kif18A
Jason Stumpff et al.
MOLECULAR CELL (2011)
External forces control mitotic spindle positioning
Jenny Fink et al.
NATURE CELL BIOLOGY (2011)
Augmin Plays a Critical Role in Organizing the Spindle and Phragmoplast Microtubule Arrays in Arabidopsis
Chin-Min Kimmy Ho et al.
PLANT CELL (2011)
Augmin promotes meiotic spindle formation and bipolarity in Xenopus egg extracts
Sabine Petry et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Examining the dynamics of chromosomal passenger complex (CPC)-dependent phosphorylation during cell division
Lei Tan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Mitotic Spindle Assembly around RCC1-Coated Beads in Xenopus Egg Extracts
David Halpin et al.
PLOS BIOLOGY (2011)
A Minimal Midzone Protein Module Controls Formation and Length of Antiparallel Microtubule Overlaps
Peter Bieling et al.
CELL (2010)
Insights into Antiparallel Microtubule Crosslinking by PRC1, a Conserved Nonmotor Microtubule Binding Protein
Radhika Subramanian et al.
CELL (2010)
The Kinesin-8 Kif18A Dampens Microtubule Plus-End Dynamics
Yaqing Du et al.
CURRENT BIOLOGY (2010)
CDK5RAP2 stimulates microtubule nucleation by the γ-tubulin ring complex
Yuk-Kwan Choi et al.
JOURNAL OF CELL BIOLOGY (2010)
Poleward Transport of TPX2 in the Mammalian Mitotic Spindle Requires Dynein, Eg5, and Microtubule Flux
Nan Ma et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Tension directly stabilizes reconstituted kinetochore-microtubule attachments
Bungo Akiyoshi et al.
NATURE (2010)
The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores
Ram Kumar Mishra et al.
NATURE CELL BIOLOGY (2010)
The Distribution of Polar Ejection Forces Determines the Amplitude of Chromosome Directional Instability
Kevin Ke et al.
CURRENT BIOLOGY (2009)
Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability
Samuel F. Bakhoum et al.
CURRENT BIOLOGY (2009)
Motor-Independent Targeting of CLASPs to Kinetochores by CENP-E Promotes Microtubule Turnover and Poleward Flux
Stefano Maffini et al.
CURRENT BIOLOGY (2009)
Compression Regulates Mitotic Spindle Length by a Mechanochemical Switch at the Poles
Sophie Dumont et al.
CURRENT BIOLOGY (2009)
Spindle Assembly in the Absence of a RanGTP Gradient Requires Localized CPC Activity
Thomas J. Maresca et al.
CURRENT BIOLOGY (2009)
Kif15 Cooperates with Eg5 to Promote Bipolar Spindle Assembly
Marvin E. Tanenbaum et al.
CURRENT BIOLOGY (2009)
The Role of Hklp2 in the Stabilization and Maintenance of Spindle Bipolarity
David Vanneste et al.
CURRENT BIOLOGY (2009)
HAUS, the 8-Subunit Human Augmin Complex, Regulates Centrosome and Spindle Integrity
Steffen Lawo et al.
CURRENT BIOLOGY (2009)
Dynein Antagonizes Eg5 by Crosslinking and Sliding Antiparallel Microtubules
Nick P. Ferenz et al.
CURRENT BIOLOGY (2009)
Synchronizing chromosome segregation by flux-dependent force equalization at kinetochores
Irina Matos et al.
JOURNAL OF CELL BIOLOGY (2009)
Kinetochore-generated pushing forces separate centrosomes during bipolar spindle assembly
Alberto Toso et al.
JOURNAL OF CELL BIOLOGY (2009)
Sequential phosphorylation of Nedd1 by Cdk1 and Plk1 is required for targeting of the gamma TuRC to the centrosome
Xiaoyan Zhang et al.
JOURNAL OF CELL SCIENCE (2009)
Kinesin-5-dependent Poleward Flux and Spindle Length Control in Drosophila Embryo Mitosis
Ingrid Brust-Mascher et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
Kinesin-14 Family Proteins HSET/XCTK2 Control Spindle Length by Cross-Linking and Sliding Microtubules
Shang Cai et al.
MOLECULAR BIOLOGY OF THE CELL (2009)
A mechanism linking extra centrosomes to chromosomal instability
Neil J. Ganem et al.
NATURE (2009)
Probing the mechanical architecture of the vertebrate meiotic spindle
Takeshi Itabashi et al.
NATURE METHODS (2009)
Plk1-Dependent Recruitment of γ-Tubulin Complexes to Mitotic Centrosomes Involves Multiple PCM Components
Laurence Haren et al.
PLOS ONE (2009)
The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells
Ryota Uehara et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Microtubule-Driven Multimerization Recruits ase1p onto Overlapping Microtubules
Lukas C. Kapitein et al.
CURRENT BIOLOGY (2008)
Evidence for an upper limit to mitotic spindle length
Martin Wuehr et al.
CURRENT BIOLOGY (2008)
The kinesin-8 motor Kif18A suppresses kinetochore movements to control mitotic chromosome alignment
Jason Stumpff et al.
DEVELOPMENTAL CELL (2008)
Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly
Marvin E. Tanenbaum et al.
EMBO JOURNAL (2008)
Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A
Alexander W. Bird et al.
JOURNAL OF CELL BIOLOGY (2008)
Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
Gohta Goshima et al.
JOURNAL OF CELL BIOLOGY (2008)
FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle
Hui Zhu et al.
JOURNAL OF CELL BIOLOGY (2008)
CDK5RAP2 is a pericentriolar protein that functions in centrosomal attachment of the gamma-tubulin ring complex
Ka-Wing Fong et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
A torque component present in mitotic kinesin Eg5 revealed by three-dimensional tracking
Junichiro Yajima et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Human cep192 is required for mitotic centrosome and spindle assembly
Maria Ana Gomez-Ferreria et al.
CURRENT BIOLOGY (2007)
Architectural dynamics of the meiotic spindle revealed by single-fluorophore imaging
Ge Yang et al.
NATURE CELL BIOLOGY (2007)
Slide-and-cluster models for spindle assembly
Kendra S. Burbank et al.
CURRENT BIOLOGY (2007)
Self-organization of MTOCs replaces Centrosome Function during Acentrosomal Spindle Assembly in Live Mouse Oocytes
Melina Schuh et al.
CELL (2007)
Tension applied through the Dam1 complex promotes microtubule elongation providing a direct mechanism for length control in mitosis
Andrew D. Franck et al.
NATURE CELL BIOLOGY (2007)
Nonredundant functions of kinesin-13s during meiotic spindle assembly
Ryoma Ohi et al.
CURRENT BIOLOGY (2007)
A centriole- and RanGTP-independent spindle assembly pathway in meiosis I of vertebrate oocytes
Julien Dumont et al.
JOURNAL OF CELL BIOLOGY (2007)
Kinetochore microtubule dynamics and attachment stability are regulated by Hec1
Jennifer G. DeLuca et al.
CELL (2006)
ELYS is a dual nucleoporin/kinetochore protein required for nuclear pore assembly and proper cell division
Beth A. Rasala et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A new method reveals microtubule minus ends throughout the meiotic spindle
Kendra S. Burbank et al.
JOURNAL OF CELL BIOLOGY (2006)
The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly
Arturo V. Orjalo et al.
MOLECULAR BIOLOGY OF THE CELL (2006)
Yeast kinesin-8 depolymerizes microtubules in a length-dependent manner
Vladimir Varga et al.
NATURE CELL BIOLOGY (2006)
Kinesin 5-independent poleward flux of kinetochore microtubules in PtK1 cells
LA Cameron et al.
JOURNAL OF CELL BIOLOGY (2006)
HURP is part of a ran-dependent complex involved in spindle formation
MD Koffa et al.
CURRENT BIOLOGY (2006)
HURP is a ran-importin β-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes
HHW Silljé et al.
CURRENT BIOLOGY (2006)
Analysis of a RanGTP-regulated gradient in mitotic somatic cells
P Kaláb et al.
NATURE (2006)
Molecular requirements for kinetochore-associated microtubule formation in mammalian cells
US Tulu et al.
CURRENT BIOLOGY (2006)
NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
L Haren et al.
JOURNAL OF CELL BIOLOGY (2006)
GCP-WD is a γ-tubulin targeting factor required for centrosomal and chromatin-mediated microtubule nucleation
J Lüders et al.
NATURE CELL BIOLOGY (2006)
Efficient mitosis in human cells lacking poleward microtubule flux
NJ Ganem et al.
CURRENT BIOLOGY (2005)
Mechanisms for focusing mitotic spindle poles by minus end-directed motor proteins
G Goshima et al.
JOURNAL OF CELL BIOLOGY (2005)
The extracellular matrix guides the orientation of the cell division axis
M Théry et al.
NATURE CELL BIOLOGY (2005)
Microtubule movements on the arms of mitotic chromosomes:: Polar ejection forces quantified in vitro
GJ Brouhard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles
TJ Mitchison et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Efficient chromosome capture requires a bias in the 'search-and-capture' process during mitotic-spindle assembly
R Wollman et al.
CURRENT BIOLOGY (2005)
The bipolar mitotic kinesin Eg5 moves on both microtubules that it crosslinks
LC Kapitein et al.
NATURE (2005)
Drosophila CLASP is required for the incorporation of microtubule subunits into fluxing kinetochore fibres
H Maiato et al.
NATURE CELL BIOLOGY (2005)
Stathmin-tubulin interaction gradients in motile and mitotic cells
P Niethammer et al.
SCIENCE (2004)
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity
WJ Lan et al.
CURRENT BIOLOGY (2004)
Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase
GC Rogers et al.
NATURE (2004)
Mitosis-specific anchoring of γ tubulin complexes by pericentrin controls spindle organization and mitotic entry
WC Zimmerman et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Kinetochore-driven formation of kinetochore fibers contributes to spindle assembly during animal mitosis
H Maiato et al.
JOURNAL OF CELL BIOLOGY (2004)
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles
DT Miyamoto et al.
JOURNAL OF CELL BIOLOGY (2004)
Characterization of the TPX2 domains involved in microtubule nucleation and spindle assembly in Xenopus egg extracts
S Brunet et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
The chromosomal passenger complex is required for chromatin-induced microtubule stabilization and spindle assembly
SC Sampath et al.
CELL (2004)
Borealin: a novel chromosomal passenger required for stability of the bipolar mitotic spindle
R Gassmann et al.
JOURNAL OF CELL BIOLOGY (2004)
Contribution of noncentrosomal microtubules to spindle assembly in Drosophila spermatocytes
E Rebollo et al.
PLOS BIOLOGY (2004)
Mammalian pins is a conformational switch that links NuMA to heterotrimeric G proteins
QS Du et al.
CELL (2004)
Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by aurora B-dependent phosphorylation
R Ohi et al.
MOLECULAR BIOLOGY OF THE CELL (2004)
Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles:: implications for spindle mechanics
P Maddox et al.
JOURNAL OF CELL BIOLOGY (2003)
Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo
M Gotta et al.
CURRENT BIOLOGY (2003)
Minus-end capture of preformed kinetochore fibers contributes to spindle morphogenesis
A Khodjakov et al.
JOURNAL OF CELL BIOLOGY (2003)
PRC1 is a microtubule binding and bundling protein essential to maintain the mitotic spindle midzone
C Mollinari et al.
JOURNAL OF CELL BIOLOGY (2002)
Visualization of a Ran-GTP gradient in interphase and mitotic Xenopus egg extracts
P Kalab et al.
SCIENCE (2002)
Organized microtubule arrays in γ-tubulin-depleted Drosophila spermatocytes
P Sampaio et al.
CURRENT BIOLOGY (2001)
Physical properties determining self-organization of motors and microtubules
T Surrey et al.
SCIENCE (2001)
Role of importin-β in coupling ran to downstream targets in microtubule assembly
C Wiese et al.
SCIENCE (2001)
Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity
OJ Gruss et al.
CELL (2001)
Importin β is a mitotic target of the small GTPase ran in spindle assembly
MV Nachury et al.
CELL (2001)
Xkid, a chromokinesin required for chromosome alignment on the metaphase plate
C Antonio et al.
CELL (2000)
The Xenopus chromokinesin Xkid is essential for metaphase chromosome alignment and must be degraded to allow anaphase chromosome movement
H Funabiki et al.
CELL (2000)
Formation of spindle poles by dynein/dynactin-dependent transport of NuMA
A Merdes et al.
JOURNAL OF CELL BIOLOGY (2000)
Centrosome-independent mitotic spindle formation in vertebrates
A Khodjakov et al.
CURRENT BIOLOGY (2000)