4.6 Editorial Material

Approval of teplizumab: implications for patients

Journal

NATURE REVIEWS ENDOCRINOLOGY
Volume 19, Issue 7, Pages 377-378

Publisher

NATURE PORTFOLIO
DOI: 10.1038/s41574-023-00849-w

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Type 1 diabetes mellitus (T1DM) can be predicted and altered by immune therapy. The FDA's approval of teplizumab as the first disease-modifying therapy for T1DM and delaying the clinical onset of any immune-mediated disease represents a paradigm shift in the treatment of T1DM.
Type 1 diabetes mellitus (T1DM) can be predicted, and immune therapy can alter the progression of the disease. The FDA's approval of teplizumab as the first disease-modifying therapy for T1DM and the first therapy aimed at delaying the clinical onset of any immune-mediated disease represents a paradigm shift in the treatment of T1DM.

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