4.7 Article

Novel mouse models based on intersectional genetics to identify and characterize plasmacytoid dendritic cells

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

flowCut: An R package for automated removal of outlier events and flagging of files based on time versus fluorescence analysis

Justin Meskas et al.

Summary: Technical artifacts in flow cytometry data acquisition can impact data quality, but flowCut, an R package, can automatically detect anomalies and improve analysis results.

CYTOMETRY PART A (2023)

Review Immunology

Dendritic cell functions in vivo: A user's guide to current and next- generation mutant mouse models

Marc Dalod et al.

Summary: DCs play a crucial role in antigen presentation and orchestrate information transfer in the immune system. Mouse models provide valuable insights into the different functions of DC types and their activation states. This article provides comprehensive information on selecting mutant mouse strains for DC research and discusses the advantages, limitations, and future perspectives of these models.

EUROPEAN JOURNAL OF IMMUNOLOGY (2022)

Article Immunology

Clonal lineage tracing reveals shared origin of conventional and plasmacytoid dendritic cells

Jue Feng et al.

Summary: This study investigates the developmental origins of dendritic cells (DCs) and reveals the shared origin of pDCs and cDCs, suggesting a revised scheme of DC development.

IMMUNITY (2022)

Review Immunology

Dual Nature of Type I Interferons in SARS-CoV-2-Induced Inflammation

Cecile King et al.

Summary: Inhibition of IFN-I by SARS-CoV-2 can worsen the disease and affect the immune response, but therapeutic boosting of IFN-I has a narrow time window for efficacy. Further research is needed to explore therapeutic approaches and vaccine design to counteract this limitation.

TRENDS IN IMMUNOLOGY (2021)

Article Immunology

Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice

Susanne Stutte et al.

Summary: Loss of appetite, commonly seen in infectious diseases, cancer, and trauma, is poorly understood in terms of its initiation and endocrine regulation during antiviral immune responses. The hormonal modulation of ghrelin through somatostatin and the cytokine IFN-I plays a critical role in optimizing antiviral immunity, despite the negative impact on calorie intake.

BRAIN BEHAVIOR AND IMMUNITY (2021)

Article Immunology

Dendritic Cells Require TMEM176A/B Ion Channels for Optimal MHC Class II Antigen Presentation to Naive CD4+ T Cells

Melanie Lancien et al.

Summary: This study investigated the role of TMEM176A/B in DCs and found that they are crucial for antigen processing and presentation to CD4(+) T cells, suggesting a direct role in the MHC class II compartment for fine regulation of antigen presentation and CD4(+) T cell priming.

JOURNAL OF IMMUNOLOGY (2021)

Article Multidisciplinary Sciences

Natural killer cells and dendritic epidermal γδ T cells orchestrate type 1 conventional DC spatiotemporal repositioning toward CD8+ T cells

Sonia Ghilas et al.

Summary: Successful immune responses require the right signals to be delivered to the right cells at the right time. In the spleen and skin, NK cells and DETCs interact with cDC1 to accelerate antiviral CD8(+) T cell responses, bridging innate and adaptive immunity through additional mechanisms.

ISCIENCE (2021)

Article Biochemical Research Methods

PARC: ultrafast and accurate clustering of phenotypic data of millions of single cells

Shobana V. Stassen et al.

BIOINFORMATICS (2020)

Article Multidisciplinary Sciences

A conserved dendritic-cell regulatory program limits antitumour immunity

Barbara Maier et al.

NATURE (2020)

Article Biotechnology & Applied Microbiology

Dimensionality reduction for visualizing single-cell data using UMAP

Etienne Becht et al.

NATURE BIOTECHNOLOGY (2019)

Article Biotechnology & Applied Microbiology

Integrating single-cell transcriptomic data across different conditions, technologies, and species

Andrew Butler et al.

NATURE BIOTECHNOLOGY (2018)

Article Immunology

Distinct progenitor lineages contribute to the heterogeneity of plasmacytoid dendritic cells

Patrick Fernandes Rodrigues et al.

NATURE IMMUNOLOGY (2018)

Article Biochemistry & Molecular Biology

Molecular dissection of plasmacytoid dendritic cell activation in vivo during a viral infection

Elena Tomasello et al.

EMBO JOURNAL (2018)

Article Multidisciplinary Sciences

Mapping the human DC lineage through the integration of high-dimensional techniques

Peter See et al.

SCIENCE (2017)

Review Immunology

The Peyer's Patch Mononuclear Phagocyte System at Steady State and during Infection

Clement Da Silva et al.

FRONTIERS IN IMMUNOLOGY (2017)

Article Immunology

Leukemia-associated activating mutation of Flt3 expands dendritic cells and alters T cell responses

Colleen M. Lau et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2016)

Article Cell Biology

Innate and Adaptive Immune Functions of Peyer's Patch Monocyte-Derived Cells

Johnny Bonnardel et al.

CELL REPORTS (2015)

Article Immunology

PACSIN1 regulates the TLR7/9-mediated type I interferon response in plasmacytoid dendritic cells

Eiji Esashi et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2012)

Article Multidisciplinary Sciences

CX3CR1+ CD8α+ dendritic cells are a steady-state population related to plasmacytoid dendritic cells

Liat Bar-On et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Multidisciplinary Sciences

Visualization of IFNβ production by plasmacytoid versus conventional dendritic cells under specific stimulation conditions in vivo

Stefanie Scheu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

CCR9 is a homing receptor for plasmacytoid dendritic cells to the small intestine

Meike Wendland et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Multidisciplinary Sciences

A clonogenic bone marrow progenitor specific for macrophages and dendritic cells

DK Fogg et al.

SCIENCE (2006)