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NATURE CHEMICAL BIOLOGY
Volume -, Issue -, Pages -Publisher
NATURE PORTFOLIO
DOI: 10.1038/s41589-023-01348-9
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A new pH nanosensor is developed to quantify the acidity level of lysosomes in cells and tumors by detecting shifts in near-infrared emission bands.
Lysosomal hyperacidification is regarded as a hallmark of autophagy. A new pH nanosensor that detects shifts in near-infrared emission bands is used to quantify cellular and intratumoral lysosomal pH.
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