4.6 Article

Latest advances on MXenes in biomedical research and health care

Journal

MRS BULLETIN
Volume 48, Issue 3, Pages 283-290

Publisher

SPRINGER HEIDELBERG
DOI: 10.1557/s43577-023-00480-0

Keywords

MXene; Bioelectronics; Biosensing; Tissue engineering; Therapeutics; Clinical translation

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The unique physical and chemical properties of MXenes have led to an increasing number of applications in biomedicine and healthcare. The expanding library of MXenes with customizable properties is enabling high-performance, application-specific MXene-based sensing and therapeutic platforms. This article highlights the emerging biomedical applications of MXenes, focusing on bioelectronics, biosensors, tissue engineering, and therapeutics. Examples of MXenes and their composites are presented, showcasing novel technological platforms and therapeutic strategies, and potential avenues for further developments are discussed. Finally, the materials, manufacturing, and regulatory challenges for the clinical translation of MXene-based biomedical technologies are addressed.
The unique combination of physical and chemical properties of MXenes has propelled a growing number of applications in biomedicine and healthcare. The expanding library of MXenes with tunable properties is paving the way for high-performance, application-specific MXene-based sensing and therapeutic platforms. In this article, we highlight the emerging biomedical applications of MXenes with specific emphasis on bioelectronics, biosensors, tissue engineering, and therapeutics. We present examples of MXenes and their composites enabling novel technological platforms and therapeutic strategies, and elucidate potential avenues for further developments. Finally, we discuss the materials, manufacturing, and regulatory challenges that need to be synergistically addressed for the clinical translation of MXene-based biomedical technologies.

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