Journal
MOLECULES
Volume 28, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/molecules28052204
Keywords
marine natural products; indole; pharmacological activity; total synthesis; lead compound
Ask authors/readers for more resources
The ocean is an important source of natural products, and in recent years, researchers have made significant progress in the fields of separation and extraction, derivative synthesis, structural studies, and biological evaluation of marine natural products. This review focuses on marine indole natural products with good pharmacological activity and research value, including monomeric indoles, indole peptides, bis-indoles, and annelated indoles. Most of these compounds exhibit cytotoxic, antiviral, antifungal, or anti-inflammatory activities.
The ocean has always been one of the important sources of natural products. In recent years, many natural products with different structures and biological activities have been obtained, and their value has been clearly recognized. Researchers have been deeply engaged in the field of separation and extraction, derivative synthesis, structural studies, biological evaluation, and other fields of research for marine natural products. Thus, a series of marine indole natural products which have structural and biological prospect have caught our eyes. In this review, we summarize some of these marine indole natural products with relatively good pharmacological activity and research value, and discuss issues concerning chemistry, pharmacological activity, biological evaluation, and synthesis, including monomeric indoles, indole peptides, bis-indoles, and annelated indoles. Most of the compounds have cytotoxic, antiviral, antifungal, or anti-inflammatory activities.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available