4.6 Article

New Bisabolane-Type Sesquiterpenoids from Curcuma longa and Their Anti-Atherosclerotic Activity

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Inflammatory Cells in Atherosclerosis

Marcelle Mehu et al.

Summary: Atherosclerosis is a chronic disease characterized by damage to the intima, inflammatory cell recruitment, and lipid accumulation followed by calcification and plaque rupture. Inflammation is believed to play a crucial role in the development and progression of the disease. This paper discusses the various types of inflammatory cells involved in atherosclerosis and their significance in the disease's development and progression. Understanding the role of these cells at different stages of the disease provides valuable insights for targeted therapy.

ANTIOXIDANTS (2022)

Review Biochemistry & Molecular Biology

Atherosclerosis: Recent developments

Johan L. M. Bjoerkegren et al.

Summary: This article reviews the current understanding of the molecular, cellular, genetic, and environmental contributions to atherosclerosis and highlights recent developments and unexpected biological findings, such as the heterogeneity of inflammatory and smooth muscle cells in lesions, the roles of senescence and clonal hematopoiesis, and the links to the gut microbiome.
Review Food Science & Technology

A review on selected pharmacological activities of Curcuma longa L

B. Jyotirmayee et al.

Summary: Turmeric, a significant spice, possesses various active biochemical activities, including anti-inflammatory, antioxidant, antibacterial, and hypoglycemic qualities. It is extensively studied in the medical industry and used for the treatment of multiple diseases.

INTERNATIONAL JOURNAL OF FOOD PROPERTIES (2022)

Article Plant Sciences

Vasorelaxant effect of curcubisabolanin A isolated from Curcuma longa through the PI3K/Akt/eNOS signaling pathway

Jin-Feng Chen et al.

Summary: The study isolated a new bisabolane-type sesquiterpenoid, curcubisabolanin A, from Curcuma longa, which exhibited vasorelaxant effects partially dependent on endothelial cells and regulated NO production in vascular endothelial cells through the PI3K/Akt/eNOS signaling pathway.

JOURNAL OF ETHNOPHARMACOLOGY (2022)

Review Biochemistry & Molecular Biology

Experimental and clinical reports on anti-inflammatory, antioxidant, and immunomodulatory effects of Curcuma longa and curcumin, an updated and comprehensive review

Arghavan Memarzia et al.

Summary: Curcuma longa and its main constituent, curcumin, exhibit anti-inflammatory, antioxidant, and immunomodulatory effects, reducing inflammatory mediators, oxidative stress, and immune system disturbances.

BIOFACTORS (2021)

Article Biochemistry & Molecular Biology

Bisabolane-type sesquiterpenoids: Structural diversity and biological activity

Hong-Zhen Shu et al.

Summary: Bisabolane-type sesquiterpenoids are a class of monocyclic sesquiterpenoids widely distributed in nature, with antibacterial, anti-inflammatory, and cytotoxic effects being the most commonly reported pharmacological properties. These compounds have been used in traditional medicines for a long time and show great potential for the development of new drugs.

PHYTOCHEMISTRY (2021)

Article Biochemistry & Molecular Biology

Bisabolane-type sesquiterpenoids from Curcuma longa L. exert anti-influenza and anti-inflammatory activities through NF-κB/MAPK and RIG-1/STAT1/2 signaling pathways

Huihui Ti et al.

Summary: Bisabolane-type sesquiterpenoids from Curcuma longa exhibit antiviral and anti-inflammatory activities against H1N1, as well as the ability to regulate host immune response. These compounds can inhibit viral replication, reduce pro-inflammatory cytokine production, and modulate signaling pathways involved in immune responses.

FOOD & FUNCTION (2021)

Review Cardiac & Cardiovascular Systems

Transcriptional and epigenetic regulation of macrophages in atherosclerosis

Tatyana Kuznetsova et al.

NATURE REVIEWS CARDIOLOGY (2020)

Review Pharmacology & Pharmacy

Statins: Adverse reactions, oxidative stress and metabolic interactions

Aimei Liu et al.

PHARMACOLOGY & THERAPEUTICS (2019)

Article Chemistry, Organic

Two New Bisabolane-Type Sesquiterpenoids from Curcuma longa

Chao Huang et al.

CHINESE JOURNAL OF ORGANIC CHEMISTRY (2018)

Review Integrative & Complementary Medicine

Holistic Regulation of Angiogenesis with Chinese Herbal Medicines as a New Option for Coronary Artery Disease

Rong Yuan et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2018)

Article Gastroenterology & Hepatology

Cholesterol and Lipoprotein Metabolism and Atherosclerosis: Recent Advances in Reverse Cholesterol Transport

Helen H. Wang et al.

ANNALS OF HEPATOLOGY (2017)

Article Cardiac & Cardiovascular Systems

Heart Disease and Stroke Statistics-2017 Update A Report From the American Heart Association

Emelia J. Benjamin et al.

CIRCULATION (2017)

Article Agriculture, Multidisciplinary

Absolute Configurations and NO Inhibitory Activities of Terpenoids from Curcuma longa

Jing Xu et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2015)

Article Chemistry, Organic

Biomimetic Total Synthesis of Meiogynin A, an Inhibitor of Bcl-xL, and Bak Interaction

Dalia Fomekong Fotsop et al.

JOURNAL OF ORGANIC CHEMISTRY (2010)

Article Chemistry, Multidisciplinary

cclib: A library for package-independent computational chemistry algorithms

Noel M. O'Boyle et al.

JOURNAL OF COMPUTATIONAL CHEMISTRY (2008)

Article Chemistry, Multidisciplinary

Total synthesis, revised structure, and biological evaluation of biyouyanagin A and analogues thereof

K. C. Nicolaou et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)