☆ 4.6 Article

The Nature of the (Oligo/Hetero)Arene Linker Connecting Two Triarylborane Cations Controls Fluorimetric and Circular Dichroism Sensing of Various ds-DNAs and ds-RNAs

MOLECULES (2023)

Related references

Note: Only part of the references are listed.

Article Biochemistry & Molecular Biology

Lighting-Up the Far-Red Fluorescence of RNA-Selective Dyes by Switching from Ortho to Para Position

Alessio Cesaretti et al.

Summary: Fluorescence imaging is seeking new far-red emitting probes that selectively respond to specific biological targets. Cationic push-pull dyes, with their intramolecular charge transfer (ICT) character and strong interaction with nucleic acids, show promise in meeting these requirements. In this study, two isomers of push-pull dimethylamino-phenyl dyes were examined for their ICT dynamics, DNA/RNA affinity, and in vitro behavior. The para-quinolinium derivative exhibited RNA-selectivity, localizing in nucleoli and mitochondria with fluorescence microscopy. It also showed potential as a theranostic agent with improved turn-on response and localized staining ability.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2023)

Add to Collection

Review Chemistry, Multidisciplinary

Applications of triarylborane materials in cell imaging and sensing of bio-relevant molecules such as DNA, RNA, and proteins

Sarina M. Berger et al.

Summary: Triarylboranes, known for more than 100 years, have potential applications in organic optoelectronics and have been recently explored in biological applications such as bioimaging and biomolecule sensing.

MATERIALS HORIZONS (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Electron-Rich EDOT Linkers in Tetracationic bis-Triarylborane Chromophores: Influence on Water Stability, Biomacromolecule Sensing, and Photoinduced Cytotoxicity

Matthias Ferger et al.

Summary: This study synthesized three novel tetracationic bis-triarylboranes with 3,4-ethylenedioxythiophene (EDOT) linkers, resulting in red-shifted absorption and emission. One of the EDOT derivatives emitted in the near-infrared (NIR) region. Comparative analysis showed that only the EDOT-linked trixylylborane tetracation was stable in aqueous solution, suggesting the insufficient hydrolytic stability of directly attaching thiophene or 3-methylthiophene to the boron atom. Furthermore, the EDOT-linked trixylylborane tetracation and its bis-thiophene analogue exhibited efficient photo-induced singlet oxygen production with significant biological implications.

CHEMISTRY-A EUROPEAN JOURNAL (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Diethynylarene-linked bis(triarylborane)cations as theranostic agents for tumor cell and virus-targeted photodynamic therapy

Ksenija Bozinovic et al.

Summary: We reported a new type of compound that shows remarkable sensing ability in DNA/RNA and also exhibits biological activity in photodynamic therapy, making them potential therapeutic probes. These compounds can effectively enter living cells with negligible inhibition on cell proliferation. Regarding viruses, some of these compounds have high affinity to adenovirus type 5 and can weaken its ability to infect human cells. Upon visible light irradiation, these compounds generate reactive oxygen species, resulting in a significant increase in cytotoxicity and antiviral activity.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Diethynylarene-linked bis(triarylborane)cations as theranostic agents for tumor cell and virus-targeted photodynamic therapy

Ksenija Bozinovic et al.

Summary: This study shows that specific compounds can increase cytotoxicity and antiviral activity through irradiation, possibly related to the generation of reactive oxygen species.

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Bis(phenylethynyl)arene Linkers in Tetracationic Bis-triarylborane Chromophores Control Fluorimetric and Raman Sensing of Various DNAs and RNAs

Matthias Ferger et al.

Summary: The new luminescent tetracationic bis-triarylborane DNA and RNA sensors exhibit high binding affinities, with substituted bis(2,6-dimethylphenyl-4-ethynyl)arene linkers serving as efficient dual Raman and fluorescence chromophores. The linker length and flexibility significantly affect the binding affinities, with triple bonds playing a crucial role in Raman activity. The insertion of aromatic moieties between two carbon-carbon triple bonds offers an alternative design for dual Raman and fluorescence chromophores in biological imaging applications.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

Add to Collection

Article Chemistry, Applied

A photosensitizing perylenediimide dye lights up cell nucleolus through visible light-mediated intracellular translocation

Tao Deng et al.

Summary: The fluorescent photosensitizer PDI-1 targets lysosomes and shows uncommon inter-organelle translocation under continual visible light irradiation; The cell nucleolus is lit up by PDI-1 in a photo-controllable manner, mainly targeting RNAs; Minor modifications to the structure of PDI-1 result in no obvious photo-induced redistribution in PDI-2 and PDI-3, emphasizing the significant impact of structural changes on photobiological behavior.

DYES AND PIGMENTS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Bithiophene-Cored, mono-, bis-, and tris-(Trimethylammonium)-Substituted, bis-Triarylborane Chromophores: Effect of the Number and Position of Charges on Cell Imaging and DNA/RNA Sensing

Sarina M. Berger et al.

Summary: This study presents the synthesis, photophysical, and electrochemical properties of selectively mono-, bis- and tris-dimethylamino- and trimethylammonium-substituted bis-triarylborane bithiophene chromophores, as well as the water solubility and singlet oxygen sensitizing efficiency of cationic compounds. The research highlights the significant influence of the bridging unit on the properties of bis-triarylboranes, especially the cationic compounds, and investigates their interactions with DNA, RNA, and DNApore in buffered solutions. Additionally, the study explores the compounds' ability to enter and localize within organelles of human lung carcinoma and normal lung cells, showing that both the number and distribution of charges on the chromophore affect interactions and staining properties.

CHEMISTRY-A EUROPEAN JOURNAL (2021)

Add to Collection

Article Chemistry, Multidisciplinary

A Quadrupolar Bis-Triarylborane Chromophore as a Fluorimetric and Chirooptic Probe for Simultaneous and Selective Sensing of DNA, RNA and Proteins

Zeljka Ban et al.

CHEMISTRY-A EUROPEAN JOURNAL (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Tetracationic Bis-Triarylborane 1,3-Butadiyne as a Combined Fluorimetric and Raman Probe for Simultaneous and Selective Sensing of Various DNA, RNA, and Proteins

Hashem Amini et al.

CHEMISTRY-A EUROPEAN JOURNAL (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Optimization of Aqueous Stability versus π-Conjugation in Tetracationic Bis(triarylborane) Chromophores: Applications in Live-Cell Fluorescence Imaging

Stefanie Griesbeck et al.

CHEMISTRY-A EUROPEAN JOURNAL (2019)

Add to Collection

Article Chemistry, Multidisciplinary

The Effect of Branching on the One- and Two-Photon Absorption, Cell Viability, and Localization of Cationic Triarylborane Chromophores with Dipolar versus Octupolar Charge Distributions for Cellular Imaging

Stefanie Griesbeck et al.

CHEMISTRY-A EUROPEAN JOURNAL (2019)

Add to Collection

Article Chemistry, Analytical

A nucleic acid-specific fluorescent probe for nucleolus imaging in living cells

Kailun Deng et al.

TALANTA (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Tuning the π-bridge of quadrupolar triarylborane chromophores for one- and two-photon excited fluorescence imaging of lysosomes in live cells

Stefanie Griesbeck et al.

CHEMICAL SCIENCE (2019)

Add to Collection

Review Chemistry, Organic

Polarization spectroscopy methods in the determination of interactions of small molecules with nucleic acids - tutorial

Tamara Smidlehner et al.

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Recent developments in and perspectives on three-coordinate boron materials: a bright future

Lei Ji et al.

CHEMICAL SCIENCE (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Water-Soluble Triarylborane Chromophores for One- and Two-Photon Excited Fluorescence Imaging of Mitochondria in Cells

Stefanie Griesbeck et al.

CHEMISTRY-A EUROPEAN JOURNAL (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Kinetic Differentiation between Homo- and Alternating AT DNA by Sterically Restricted Phosphonium Dyes

Lidija-Marija Tumir et al.

CHEMISTRY-A EUROPEAN JOURNAL (2012)

Add to Collection

Article Chemistry, Multidisciplinary

Recognition of homo-polynucleotides containing adenine by a phenanthridinium bis-uracil conjugate in aqueous media

LM Tumir et al.

CHEMICAL COMMUNICATIONS (2005)

Add to Collection

Review Chemistry, Physical

Applications of three-coordinate organoboron compounds and polymers in optoelectronics

CD Entwistle et al.

CHEMISTRY OF MATERIALS (2004)

Add to Collection

Review Biochemistry & Molecular Biology

Analysis of thermal melting curves

JL Mergny et al.

OLIGONUCLEOTIDES (2003)

Add to Collection

Article Chemistry, Organic

A new 4,9-diazapyrenium intercalator for single- and double-stranded nucleic acids: distinct differences from related diazapyrenium compounds and ethidium bromide

I Piantanida et al.

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.