Journal
MOLECULES
Volume 28, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/molecules28052151
Keywords
green tea catechins; antioxidant; natural compounds; anticancer; mechanisms; apoptosis
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Despite decades of research and development, cancer remains a significant global threat. Green tea catechins (GTCs) have shown promise in cancer therapy, particularly when combined with other antioxidant-rich natural compounds. This review highlights the milestones achieved by GTCs and encourages further research in this area, as well as discussing the potential of combinatorial approaches in the future.
After decades of research and development concerning cancer treatment, cancer is still at large and very much a threat to the global human population. Cancer remedies have been sought from all possible directions, including chemicals, irradiation, nanomaterials, natural compounds, and the like. In this current review, we surveyed the milestones achieved by green tea catechins and what has been accomplished in cancer therapy. Specifically, we have assessed the synergistic anticarcinogenic effects when green tea catechins (GTCs) are combined with other antioxidant-rich natural compounds. Living in an age of inadequacies, combinatorial approaches are gaining momentum, and GTCs have progressed much, yet there are insufficiencies that can be improvised when combined with natural antioxidant compounds. This review highlights that there are not many reports in this specific area and encourages and recommends research attention in this direction. The antioxidant/prooxidant mechanisms of GTCs have also been highlighted. The current scenario and the future of such combinatorial approaches have been addressed, and the lacunae in this aspect have been discussed.
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