☆ 4.6 Review

Opinion: more mouse models and more translation needed for ALS

MOLECULAR NEURODEGENERATION (2023)

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Dong-Joo Cheon et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 6 (2011)

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Article Clinical Neurology

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments

Vivek Swarup et al.

BRAIN (2011)

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Article Cell Biology

A comprehensive assessment of the SOD1G93A low-copy transgenic mouse, which models human amyotrophic lateral sclerosis

Abraham Acevedo-Arozena et al.

DISEASE MODELS & MECHANISMS (2011)

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Article Medicine, Research & Experimental

Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice

Lionel M. Igaz et al.

JOURNAL OF CLINICAL INVESTIGATION (2011)

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Article Multidisciplinary Sciences

Selective activation of p53-mediated tumour suppression in high-grade tumours

Melissa R. Junttila et al.

NATURE (2010)

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Article Multidisciplinary Sciences

Somatic evolutionary genomics: Mutations during development cause highly variable genetic mosaicism with risk of cancer and neurodegeneration

Steven A. Frank

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

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Review Clinical Neurology

Prognostic factors in ALS: A critical review

Adriano Chio et al.

AMYOTROPHIC LATERAL SCLEROSIS (2009)

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Review Cell Biology

New approaches for modelling sporadic genetic disease in the mouse

Elizabeth M. C. Fisher et al.

DISEASE MODELS & MECHANISMS (2009)

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Article Clinical Neurology

Incidence and lifetime risk of motor neuron disease in the United Kingdom: a population-based study

A. Alonso et al.

EUROPEAN JOURNAL OF NEUROLOGY (2009)

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Article Multidisciplinary Sciences

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

Caroline Vance et al.

SCIENCE (2009)

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Article Multidisciplinary Sciences

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

Jemeen Sreedharan et al.

SCIENCE (2008)

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Article Multidisciplinary Sciences

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Wen Xue et al.

NATURE (2007)

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Article Biochemistry & Molecular Biology

Modeling the therapeutic efficacy of p53 restoration in tumors

Carla P. Martins et al.

CELL (2006)

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Letter Clinical Neurology

Amyotrophic lateral sclerosis in an urban setting - A population based study of inner city London

Clare A. Johnston et al.

JOURNAL OF NEUROLOGY (2006)

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Article Biochemistry & Molecular Biology

Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice

D Kieran et al.

NATURE MEDICINE (2004)

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