4.6 Article

The Integrin Pathway Partially Mediates Stretch-Induced Deficits in Primary Rat Microglia

Related references

Note: Only part of the references are listed.
Article Engineering, Biomedical

Substrate stiffness effects onSH-SY5Y: The dichotomy of morphology and neuronal behavior

Alp Ozgun et al.

Summary: Neuroblastoma cells respond to mechanical cues in their microenvironment, showing enhanced neuronal morphology on stiff substrates. However, despite more efficient neuronal differentiation in biomimetic environments, SH-SY5Y cells display morphologies conflicting with neuronal behavior under these conditions. This study provides important insights for researchers using SH-SY5Y as a neuron model.

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS (2021)

Review Neurosciences

Mechanosensation in traumatic brain injury

Carolyn E. Keating et al.

Summary: Traumatic brain injury is caused by extreme mechanical forces to the brain, leading to cellular responses and potential long-term dysfunction and degeneration. Understanding the biomechanics of TBI and how cells respond to these forces is crucial for identifying therapeutic targets for trauma-related sequelae.

NEUROBIOLOGY OF DISEASE (2021)

Article Neurosciences

Assessment of the Effects of Stretch-Injury on Primary Rat Microglia

Mike Shaughness et al.

Summary: The study demonstrates significant alterations in microglial function following stretch-injury, indicating a potential impact on their response to injury or interaction with other cells.

MOLECULAR NEUROBIOLOGY (2021)

Article Cell Biology

An optogenetic model reveals cell shape regulation through FAK and fascin

Jean A. Castillo-Badillo et al.

Summary: Optogenetic tool was utilized to investigate cell shape regulation mechanisms, revealing that FAK and fascin work together to maintain cell shape by regulating adhesion area and height in different cell types.

JOURNAL OF CELL SCIENCE (2021)

Article Medicine, Legal

Fast microglial activation after severe traumatic brain injuries

Julia Lier et al.

INTERNATIONAL JOURNAL OF LEGAL MEDICINE (2020)

Article Oncology

Focal adhesion kinase (FAK) activation by estrogens involves GPER in triple-negative breast cancer cells

Damiano Cosimo Rigiracciolo et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)

Article Cell Biology

CeO2@PAA-LXW7 Attenuates LPS-Induced Inflammation in BV2 Microglia

Jingjing Jia et al.

CELLULAR AND MOLECULAR NEUROBIOLOGY (2019)

Article Medicine, Research & Experimental

Integrin alpha5beta1 suppresses rBMSCs anoikis and promotes nitric oxide production

Hai-ying Chen et al.

BIOMEDICINE & PHARMACOTHERAPY (2018)

Article Cell Biology

Fibronectin induces macrophage migration through a SFK-FAK/CSF-1R pathway

Graziana Digiacomo et al.

CELL ADHESION & MIGRATION (2017)

Review Immunology

The Role of Microglia and Macrophages in CNS Homeostasis, Autoimmunity, and Cancer

Jie Yin et al.

JOURNAL OF IMMUNOLOGY RESEARCH (2017)

Article Multidisciplinary Sciences

LRRK2 G2019S mutation attenuates microglial motility by inhibiting focal adhesion kinase

Insup Choi et al.

NATURE COMMUNICATIONS (2015)

Article Immunology

Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury

Sean J. Cooney et al.

JOURNAL OF NEUROINFLAMMATION (2013)

Article Multidisciplinary Sciences

Stretch in Brain Microvascular Endothelial Cells (cEND) as an In Vitro Traumatic Brain Injury Model of the Blood Brain Barrier

Ellaine Salvador et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2013)

Article Biochemistry & Molecular Biology

Antibody-Mediated Inhibition of Integrin α5β1 Blocks Neurotoxic Prion Peptide PrP106-126-Induced Activation of BV2 Microglia

Jiaxin Chang et al.

JOURNAL OF MOLECULAR NEUROSCIENCE (2012)

Article Multidisciplinary Sciences

β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival

Andrea Rachelle C. Santos et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

Primary Microglia Isolation from Mixed Glial Cell Cultures of Neonatal Rat Brain Tissue

Tami T. Tamashiro et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2012)

Article Cell Biology

Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events

Michelle Y. Abshire et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2011)

Article Multidisciplinary Sciences

A Possible Role for Integrin Signaling in Diffuse Axonal Injury

Matthew A. Hemphill et al.

PLOS ONE (2011)

Article Oncology

Nm23-H1 suppresses hepatocarcinoma cell adhesion and migration on fibronectin by modulating glycosylation of integrin beta1

Shangyang She et al.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2010)

Article Biochemistry & Molecular Biology

Focal adhesion kinase can play unique and opposing roles in regulating the morphology of differentiating oligodendrocytes

Audrey D. Lafrenaye et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Article Clinical Neurology

Activation of Metabotropic Glutamate Receptor 5 Improves Recovery after Spinal Cord Injury in Rodents

Kimberly R. Byrnes et al.

ANNALS OF NEUROLOGY (2009)

Review Cell Biology

Focal adhesion kinase: In command and control of cell motility

SK Mitra et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)

Article Critical Care Medicine

Potentiation of GABAA currents after mechanical injury of cortical neurons

CQ Kao et al.

JOURNAL OF NEUROTRAUMA (2004)

Article Biochemistry & Molecular Biology

S100B protein is released by in vitro trauma and reduces delayed neuronal injury

KA Willoughby et al.

JOURNAL OF NEUROCHEMISTRY (2004)

Review Cell Biology

Get a ligand, get a life: integrins, signaling and cell survival

DG Stupack et al.

JOURNAL OF CELL SCIENCE (2002)

Review Neurosciences

The integrin family of cell adhesion molecules has multiple functions within the CNS

R Milner et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2002)

Review Biochemistry & Molecular Biology

Focal Adhesion Kinase: a regulator of focal adhesion dynamics and cell movement

JT Parsons et al.

ONCOGENE (2000)