4.8 Review

Determinants and outcomes of mitochondrial dynamics

Related references

Note: Only part of the references are listed.
Article Cell Biology

Dual role of Mic10 in mitochondrial cristae organization and ATP synthase-linked metabolic adaptation and respiratory growth

Heike Rampelt et al.

Summary: Cristae, invaginations of the mitochondrial inner membrane, are important for oxidative phosphorylation. The study reveals that Mic10, a subunit of MICOS, also interacts with the F1Fo-ATP synthase, and it plays distinct roles in cristae shaping and respiratory adaptation and growth.

CELL REPORTS (2022)

Article Multidisciplinary Sciences

Mechanical instability generated by Myosin 19 contributes to mitochondria cristae architecture and OXPHOS

Peng Shi et al.

Summary: The study reveals the critical role of myosin 19 (Myo19) in maintaining mitochondrial cristae structure and energy production, and its connection to membrane potential through its motor activity.

NATURE COMMUNICATIONS (2022)

Article Multidisciplinary Sciences

Structural insights into crista junction formation by the Mic60-Mic19 complex

Tobias Bock-Bierbaum et al.

Summary: Mitochondrial cristae membranes are where oxidative phosphorylation occurs in cells, and cristae junctions serve as selective entry gates into the cristae space. The Mic60-Mic19 subcomplex acts as a molecular strut, controlling the architecture and function of cristae junctions.

SCIENCE ADVANCES (2022)

Article Cell Biology

MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control

Tim Koenig et al.

Summary: The study characterizes a MIRO1/2- and DRP1-dependent MDV biogenesis pathway and reveals how MDVs shuttle fully assembled protein complexes to lysosomes, maintaining mitochondrial proteome quality. This provides insights into a selective quality control mechanism for multi-subunit complexes within mitochondria.

NATURE CELL BIOLOGY (2021)

Article Multidisciplinary Sciences

Actin cables and comet tails organize mitochondrial networks in mitosis

Andrew S. Moore et al.

Summary: Actin assemblies play important roles in mitochondrial organization and inheritance during mitosis, ensuring equal segregation of mitochondrial mass at cytokinesis. Actin filaments on the surface of mitochondria form comet tails, promoting randomly directed bursts of movement to randomize inheritance of healthy and damaged mitochondria between daughter cells in symmetric cell division.

NATURE (2021)

Review Multidisciplinary Sciences

Function and regulation of the divisome for mitochondrial fission

Felix Kraus et al.

Summary: Mitochondria form dynamic networks through fusion and fission events, with fission serving as an endpoint event in signaling axis for cells to sense and respond to external cues. The fission process is coordinated by membrane-associated adaptors, influenced by organellar and cytoskeletal interactions, and executed by the GTPase DRP1. Separating the functional and regulatory aspects of the 'mitochondrial divisome' into core and accessory machinery provides a mechanistic understanding of the mitochondrial fission process.

NATURE (2021)

Article Multidisciplinary Sciences

Distinct fission signatures predict mitochondrial degradation or biogenesis

Tatjana Kleele et al.

Summary: Mitochondrial fission is a highly regulated process that can impact cell function and health. Depending on the location and manner of division, mitochondria can be divided into two types, one for clearing damaged material and undergoing mitophagy, and the other for mitochondrial proliferation.

NATURE (2021)

Article Cell Biology

Mitochondrial membrane tension governs fission

Dora Mahecic et al.

Summary: This study utilized live-cell structured illumination microscopy to capture the dynamics of constricting mitochondria in mammalian cells. By analyzing the diameters of tubules emerging from mitochondria and implementing a fluorescence lifetime-based mitochondrial membrane tension sensor, it was discovered that mitochondria are indeed under tension during fission. Upon perturbations reducing mitochondrial tension, constrictions initiated at the same rate but were less likely to divide.

CELL REPORTS (2021)

Article Biochemistry & Molecular Biology

Opa1 relies on cristae preservation and ATP synthase to curtail reactive oxygen species accumulation in mitochondria

Ruben Quintana-Cabrera et al.

Summary: The study shows that the mitochondrial fusion and cristae shape protein Opa1 requires mitochondrial ATP synthase oligomers to reduce ROS accumulation. In some cells fueled with galactose to force ATP production by mitochondria, cristae are enlarged, ATP synthase oligomers destabilized, and ROS accumulate.

REDOX BIOLOGY (2021)

Article Medicine, Research & Experimental

High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts

Emma Cretin et al.

Summary: Mutations in OPA1 can cause DOA or DOA+ with severe neurological deficits, while depletion of PGS1 may help restore mitochondrial morphology and improve defects.

EMBO MOLECULAR MEDICINE (2021)

Article Multidisciplinary Sciences

ORP1L mediated PI(4)P signaling at ER-lysosome-mitochondrion three-way contact contributes to mitochondrial division

Maxime Boutry et al.

Summary: The study reveals that during mitochondrial division, the endoplasmic reticulum recruits lysosomes through the interaction of VAPs with ORP1L, creating a three-way contact between the ER, lysosomes, and mitochondria. Additionally, ORP1L may transport PI(4)P from lysosomes to mitochondria, demonstrating a direct role of PI(4)P in the fission process of mitochondria.

NATURE COMMUNICATIONS (2021)

Article Multidisciplinary Sciences

Cristae-dependent quality control of the mitochondrial genome

Christopher Jakubke et al.

Summary: The study shows that yeast can distinguish between functional and defective mtDNA, promoting the generation of healthier daughter cells. Purifying selection for functional mtDNA occurs in a continuous mitochondrial network, depending on intact cristae morphology.

SCIENCE ADVANCES (2021)

Article Biochemistry & Molecular Biology

Prohibitin levels regulate OMA1 activity and turnover in neurons

Corey J. Anderson et al.

CELL DEATH AND DIFFERENTIATION (2020)

Article Biochemistry & Molecular Biology

Cristae undergo continuous cycles of membrane remodelling in a MICOS-dependent manner

Arun Kumar Kondadi et al.

EMBO REPORTS (2020)

Article Cell Biology

Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology

Robert G. Abrisch et al.

JOURNAL OF CELL BIOLOGY (2020)

Review Cell Biology

The cell biology of mitochondrial membrane dynamics

Marta Giacomello et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)

Article Biochemistry & Molecular Biology

PIM kinases alter mitochondrial dynamics and chemosensitivity in lung cancer

Shailender S. Chauhan et al.

ONCOGENE (2020)

Article Multidisciplinary Sciences

Structural analysis of a trimeric assembly of the mitochondrial dynamin-like GTPase Mgm1

Liming Yan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Article Multidisciplinary Sciences

Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division

Shun Nagashima et al.

SCIENCE (2020)

Editorial Material Biochemistry & Molecular Biology

The last wall of defense to prevent extreme and deleterious mitochondrial fusion

Luis Carlos Tabara et al.

EMBO JOURNAL (2020)

Review Physiology

Evolving Concepts of Mitochondrial Dynamics

Gerald W. Dorn

ANNUAL REVIEW OF PHYSIOLOGY, VOL 81 (2019)

Article Biochemistry & Molecular Biology

Human Fis1 regulates mitochondrial dynamics through inhibition of the fusion machinery

Rong Yu et al.

EMBO JOURNAL (2019)

Article Biochemistry & Molecular Biology

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

Maria Isabel Hernandez-Alvarez et al.

Article Biochemistry & Molecular Biology

ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2α Axis

Eduardo Balsa et al.

MOLECULAR CELL (2019)

Letter Multidisciplinary Sciences

Mitochondrial fission requires DRP1 but not dynamins

Tiago Branco Fonseca et al.

NATURE (2019)

Article Multidisciplinary Sciences

Structure and assembly of the mitochondrial membrane remodelling GTPase Mgm1

Katja Faelber et al.

NATURE (2019)

Article Multidisciplinary Sciences

STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism

Hongxu Xian et al.

NATURE COMMUNICATIONS (2019)

Review Cell Biology

The enigma of an interconnected mitochondrial reticulum: new insights into mitochondrial fusion

Sevan Mattie et al.

CURRENT OPINION IN CELL BIOLOGY (2019)

Article Neurosciences

Surveillance and transportation of mitochondria in neurons

Roeland Vanhauwaert et al.

CURRENT OPINION IN NEUROBIOLOGY (2019)

Review Biochemistry & Molecular Biology

Functional Interplay between Cristae Biogenesis, Mitochondrial Dynamics and Mitochondrial DNA Integrity

Arun Kumar Kondadi et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Multidisciplinary Sciences

Identification of an ATP-sensitive potassium channel in mitochondria

Angela Paggio et al.

NATURE (2019)

Review Cell Biology

The Good and the Bad of Mitochondrial Breakups

Hans-Georg Sprenger et al.

TRENDS IN CELL BIOLOGY (2019)

Editorial Material Endocrinology & Metabolism

ER Stress Priming of Mitochondrial Respiratory suPERKomplex Assembly

Ruben Quintana-Cabrera et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2019)

Article Multidisciplinary Sciences

Live-cell STED nanoscopy of mitochondrial cristae

Till Stephan et al.

SCIENTIFIC REPORTS (2019)

Article Biochemistry & Molecular Biology

Who and how in the regulation of mitochondrial cristae shape and function

R. Quintana-Cabrera et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)

Article Biochemistry & Molecular Biology

Relationship between OPA1 and cardiolipin in mitochondrial inner-membrane fusion

Tadato Ban et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2018)

Article Biochemistry & Molecular Biology

The heptad repeat domain 1 of Mitofusin has membrane destabilization function in mitochondrial fusion

Frederic Daste et al.

EMBO REPORTS (2018)

Review Biochemistry & Molecular Biology

Mitochondrial dynamics: overview of molecular mechanisms

Lisa Tilokani et al.

MITOCHONDRIAL DISEASES (2018)

Article Multidisciplinary Sciences

Mitochondria-lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

Yvette C. Wong et al.

NATURE (2018)

Review Cell Biology

Phosphatidic Acid and Cardiolipin Coordinate Mitochondria! Dynamics

Shoichiro Kameoka et al.

TRENDS IN CELL BIOLOGY (2018)

Article Multidisciplinary Sciences

The cristae modulator Optic atrophy 1 requires mitochondrial ATP synthase oligomers to safeguard mitochondrial function

Ruben Quintana-Cabrera et al.

NATURE COMMUNICATIONS (2018)

Review Biochemistry & Molecular Biology

Mitochondrial Dynamics: Coupling Mitochondrial Fitness with Healthy Aging

David Sebastian et al.

TRENDS IN MOLECULAR MEDICINE (2017)

Article Cell Biology

OPA1 Isoforms in the Hierarchical Organization of Mitochondrial Functions

Valentina Del Dotto et al.

CELL REPORTS (2017)

Review Biochemistry & Molecular Biology

Proliferation and fission of peroxisomes - An update

Michael Schrader et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)

Article Medicine, Research & Experimental

SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome

Alexandre Janer et al.

EMBO MOLECULAR MEDICINE (2016)

Article Cell Biology

Structures of human mitofusin 1 provide insight into mitochondrial tethering

Yuanbo Qi et al.

JOURNAL OF CELL BIOLOGY (2016)

Article Biochemistry & Molecular Biology

Coincident Phosphatidic Acid Interaction Restrains Drp1 in Mitochondrial Division

Yoshihiro Adachi et al.

MOLECULAR CELL (2016)

Article Multidisciplinary Sciences

Correcting mitochondrial fusion by manipulating mitofusin conformations

Antonietta Franco et al.

NATURE (2016)

Article Multidisciplinary Sciences

Multiple dynamin family members collaborate to drive mitochondrial division

Jason E. Lee et al.

NATURE (2016)

Article Multidisciplinary Sciences

Critical reappraisal confirms that Mitofusin 2 is an endoplasmic reticulum-mitochondria tether

Deborah Naon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Erin Quan Toyama et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells

Samantha C. Lewis et al.

SCIENCE (2016)

Review Biochemistry & Molecular Biology

Mitochondrial Cristae: Where Beauty Meets Functionality

Sara Cogliati et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Article Multidisciplinary Sciences

Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming

Javier Prieto et al.

NATURE COMMUNICATIONS (2016)

Article Biochemistry & Molecular Biology

Regulation of mitochondrial morphology and cell cycle by microRNA-214 targeting Mitofusin2

Sudha Bucha et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)

Article Cell Biology

Mic10 Oligomerizes to Bend Mitochondrial Inner Membranes at Cristae Junctions

Mariam Barbot et al.

CELL METABOLISM (2015)

Article Cell Biology

Opa1 Overexpression Ameliorates the Phenotype of Two Mitochondrial Disease Mouse Models

Gabriele Civiletto et al.

CELL METABOLISM (2015)

Article Cell Biology

A Role for the Ancient SNARE Syntaxin 17 in Regulating Mitochondrial Division

Kohei Arasaki et al.

DEVELOPMENTAL CELL (2015)

Review Medicine, Research & Experimental

Mitochondrial dynamism and heart disease: changing shape and shaping change

Gerald W. Dorn

EMBO MOLECULAR MEDICINE (2015)

Article Cell Biology

Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels

Arnaud Mourier et al.

JOURNAL OF CELL BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Stomatin-Like Protein 2 Is Required for In Vivo Mitochondrial Respiratory Chain Supercomplex Formation and Optimal Cell Function

Panagiotis Mitsopoulos et al.

MOLECULAR AND CELLULAR BIOLOGY (2015)

Article Biochemistry & Molecular Biology

Extracellular Regulated Kinase Phosphorylates Mitofusin 1 to Control Mitochondrial Morphology and Apoptosis

Aswin Pyakurel et al.

MOLECULAR CELL (2015)

Article Cell Biology

USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria

Christian N. Cunningham et al.

NATURE CELL BIOLOGY (2015)

Article Cell Biology

ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation

Felipe K. Teixeira et al.

NATURE CELL BIOLOGY (2015)

Article Genetics & Heredity

Mutations in SLC25A46, encoding a UGO1-like protein, cause an optic atrophy spectrum disorder

Alexander J. Abrams et al.

NATURE GENETICS (2015)

Article Multidisciplinary Sciences

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice

Timothy Wai et al.

SCIENCE (2015)

Article Multidisciplinary Sciences

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

Pekka Katajisto et al.

SCIENCE (2015)

Article Biochemistry & Molecular Biology

Mitochondrial Fission Factor Drp1 Maintains Oocyte Quality via Dynamic Rearrangement of Multiple Organelles

Osamu Udagawa et al.

CURRENT BIOLOGY (2014)

Article Biochemistry & Molecular Biology

A Role for Myosin II in Mammalian Mitochondrial Fission

Farida Korobova et al.

CURRENT BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Mitochondria and Melanosomes Establish Physical Contacts Modulated by Mfn2 and Involved in Organelle Biogenesis

Tiziana Daniele et al.

CURRENT BIOLOGY (2014)

Article Biochemistry & Molecular Biology

OPA1-dependent cristae modulation is essential for cellular adaptation to metabolic demand

David A. Patten et al.

EMBO JOURNAL (2014)

Article Biochemistry & Molecular Biology

Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

Alejandro Martorell-Riera et al.

EMBO JOURNAL (2014)

Review Biochemistry & Molecular Biology

Dynamic survey of mitochondria by ubiquitin

Mafalda Escobar-Henriques et al.

EMBO REPORTS (2014)

Article Cell Biology

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission

Ruchika Anand et al.

JOURNAL OF CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Mitofusin 1 Is Negatively Regulated by MicroRNA 140 in Cardiomyocyte Apoptosis

Jincheng Li et al.

MOLECULAR AND CELLULAR BIOLOGY (2014)

Article Cell Biology

Mutations in Fis1 disrupt orderly disposal of defective mitochondria

Qinfang Shen et al.

MOLECULAR BIOLOGY OF THE CELL (2014)

Article Multidisciplinary Sciences

A Mitofusin-2-dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver

Aditi Sood et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Biochemistry & Molecular Biology

ROMO1 Is an Essential Redox-Dependent Regulator of Mitochondrial Dynamics

Matthew Norton et al.

SCIENCE SIGNALING (2014)

Article Biochemistry & Molecular Biology

The Mitochondrial Fission Receptor MiD51 Requires ADP as a Cofactor

Oliver C. Loson et al.

STRUCTURE (2014)

Article Biochemistry & Molecular Biology

Structural insights into oligomerization and mitochondrial remodelling of dynamin 1-like protein

Chris Froehlich et al.

EMBO JOURNAL (2013)

Article Biochemistry & Molecular Biology

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

Juan Pablo Munoz et al.

EMBO JOURNAL (2013)

Article Biochemistry & Molecular Biology

OPA1 promotes pH flashes that spread between contiguous mitochondria without matrix protein exchange

Jaime Santo-Domingo et al.

EMBO JOURNAL (2013)

Article Biochemistry & Molecular Biology

Adaptor Proteins MiD49 and MiD51 Can Act Independently of Mff and Fis1 in Drp1 Recruitment and Are Specific for Mitochondrial Fission

Catherine S. Palmer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

MITOL Regulates Endoplasmic Reticulum-Mitochondria Contacts via Mitofusin2

Ayumu Sugiura et al.

MOLECULAR CELL (2013)

Article Biochemistry & Molecular Biology

The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO

Anne Kathrin Mueller-Rischart et al.

MOLECULAR CELL (2013)

Article Multidisciplinary Sciences

STED super-resolution microscopy reveals an array of MINOS clusters along human mitochondria

Daniel C. Jans et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c

Reiko Ban-Ishihara et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Interchangeable adaptors regulate mitochondrial dynamin assembly for membrane scission

Sajjan Koirala et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

Age-dependent dissociation of ATP synthase dimers and loss of inner-membrane cristae in mitochondria

Bertram Daum et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Article Multidisciplinary Sciences

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

Farida Korobova et al.

SCIENCE (2013)

Article Cell Biology

Mechanisms of Mitochondrial Fission and Fusion

Alexander M. van der Bliek et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)

Article Biochemistry & Molecular Biology

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

T. Verfaillie et al.

CELL DEATH AND DIFFERENTIATION (2012)

Article Multidisciplinary Sciences

Structure of the yeast F1Fo-ATP synthase dimer and its role in shaping the mitochondrial cristae

Karen M. Davies et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

David Sebastian et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Cardiac & Cardiovascular Systems

OPA1 Mutation and Late-Onset Cardiomyopathy: Mitochondrial Dysfunction and mtDNA Instability

Le Chen et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2012)

Article Biochemistry & Molecular Biology

ChChd3, an Inner Mitochondrial Membrane Protein, Is Essential for Maintaining Crista Integrity and Mitochondrial Function

Manjula Darshi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1

Jian-Xun Wang et al.

NATURE MEDICINE (2011)

Article Biochemistry & Molecular Biology

Conformational changes in Dnm1 support a contractile mechanism for mitochondrial fission

Jason A. Mears et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)

Article Multidisciplinary Sciences

ER Tubules Mark Sites of Mitochondrial Division

Jonathan R. Friedman et al.

SCIENCE (2011)

Article Biochemistry & Molecular Biology

Novel Components of an Active Mitochondrial K+/H+ Exchange

Ludmila Zotova et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

SLP-2 is required for stress-induced mitochondrial hyperfusion

Daniel Tondera et al.

EMBO JOURNAL (2009)

Article Biochemistry & Molecular Biology

Loss of Parkin or PINK1 Function Increases Drp1-dependent Mitochondrial Fragmentation

A. Kathrin Lutz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Cell Biology

Mitochondrial outer and inner membrane fusion requires a modified carrier protein

Suzanne Hoppins et al.

JOURNAL OF CELL BIOLOGY (2009)

Article Cell Biology

Mitofusins and OPA1 Mediate Sequential Steps in Mitochondrial Membrane Fusion

Zhiyin Song et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Article Cell Biology

Regulation of mitochondrial structure and function by the F1FO-ATPase inhibitor protein, IF1

Michelangelo Campanella et al.

CELL METABOLISM (2008)

Article Biochemistry & Molecular Biology

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Gilad Twig et al.

EMBO JOURNAL (2008)

Article Cell Biology

CaM kinase lα-induced phosphorylation of Drp1 regulates mitochondrial morphology

Xiao-Jian Han et al.

JOURNAL OF CELL BIOLOGY (2008)

Article Cell Biology

The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells

Shilpa Gandre-Babbe et al.

MOLECULAR BIOLOGY OF THE CELL (2008)

Article Multidisciplinary Sciences

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

Olga Martins de Brito et al.

NATURE (2008)

Article Multidisciplinary Sciences

Mitochondrial Fusion Is Increased by the Nuclear Coactivator PGC-1β

Marc Liesa et al.

PLOS ONE (2008)

Article Multidisciplinary Sciences

Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria

G. M. Cereghetti et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

LETM1, deleted in Wolf-Hirschhorn syndrome is required for normal mitochondrial morphology and cellular viability

Kai Stefan Dimmer et al.

HUMAN MOLECULAR GENETICS (2008)

Article Biochemistry & Molecular Biology

Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology

Chuang-Rung Chang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Cell Biology

The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division

Mariusz Karbowski et al.

JOURNAL OF CELL BIOLOGY (2007)

Article Medicine, General & Internal

A lethal defect of mitochondrial and peroxisomal fission

Hans R. Waterham et al.

NEW ENGLAND JOURNAL OF MEDICINE (2007)

Article Biochemistry & Molecular Biology

Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission

Naoko Taguchi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

Christian Frezza et al.

Article Biochemistry & Molecular Biology

Regulation of mitochondrial morphology through proteolytic cleavage of OPA1

Naotada Ishihara et al.

EMBO JOURNAL (2006)

Article Cell Biology

Tagging and tracking individual networks within a complex mitochondrial web with photoactivatable GFP

Gilad Twig et al.

AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2006)

Article Cell Biology

Dnm1 forms spirals that are structurally tailored to fit mitochondria

E Ingerman et al.

JOURNAL OF CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Disruption of fusion results in mitochondrial heterogeneity and dysfunction

HC Chen et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

The modulation in subunits e and g amounts of yeast ATP synthase modifies mitochondrial cristae morphology

G Arselin et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

Structural basis of mitochondrial tethering by mitofusin complexes

T Koshiba et al.

SCIENCE (2004)

Article Biochemistry & Molecular Biology

Ugo1p links the Fzo1p and Mgm1p GTPases for mitochondrial fusion

H Sesaki et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Multidisciplinary Sciences

OPA1 requires mitofusin 1 to promote mitochondrial fusion

S Cipolat et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

Cardiolipin stabilizes respiratory chain supercomplexes

K Pfeiffer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Dynamin-like protein 1 is involved in peroxisomal fission

A Koch et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

A Olichon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Article Biochemistry & Molecular Biology

The ATP synthase is involved in generating mitochondrial cristae morphology

P Paumard et al.

EMBO JOURNAL (2002)

Article Cell Biology

Mammalian dynamin-like protein DLP1 tubulates membranes

Y Yoon et al.

MOLECULAR BIOLOGY OF THE CELL (2001)

Review Biochemistry & Molecular Biology

Topology of the mitochondrial inner membrane: Dynamics and bioenergetic implications

CA Mannella et al.

IUBMB LIFE (2001)

Article Cell Biology

Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells

E Smirnova et al.

MOLECULAR BIOLOGY OF THE CELL (2001)