4.5 Article

On-chip flow rate sensing via membrane deformation and bistability probed by microwave resonators

Journal

MICROFLUIDICS AND NANOFLUIDICS
Volume 27, Issue 4, Pages -

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s10404-023-02640-9

Keywords

Flow rate sensing; Microwave sensors; Microfluidics; Membranes; Fluid-structure interaction; Deformable microfluidics; Nonlinear microfluidics; Nanomembrane flow sensing

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Precise monitoring of fluid flow rates is crucial in lab-on-a-chip applications. This study explores the use of a 220 nm thick Silicon Nitride membrane as an on-chip sensing mechanism for flow rate measurement. By inducing mechanical deformations on the membrane through applied pressure and fluid flow, changes in capacitance and resonance frequency of an integrated microwave resonator are observed and used to track the flow rate. The membrane exhibits both deflection under pressure and pulsation under constant fluid flow, providing separate sensing mechanisms for pressure and flow rate. This research demonstrates the potential of microwave resonators for fluid-structure interactions at micro- and nanoscales.
Precise monitoring of fluid flow rates constitutes an integral problem in various lab-on-a-chip applications. While off-chip flow sensors are commonly used, new sensing mechanisms are being investigated to address the needs of increasingly complex lab-on-a-chip platforms which require local and non-intrusive flow rate sensing. In this regard, the deformability of microfluidic components has recently attracted attention as an on-chip sensing mechanism. To develop an on-chip flow rate sensor, here we utilized the mechanical deformations of a 220 nm thick Silicon Nitride membrane integrated with the microfluidic channel. Applied pressure and fluid flow induce different modes of deformations on the membrane, which are electronically probed by an integrated microwave resonator. The flow changes the capacitance, and in turn resonance frequency, of the microwave resonator. By tracking the resonance frequency, liquid flow was probed with the device. In addition to responding to applied pressure by deflection, the membrane also exhibits periodic pulsation motion under fluid flow at a constant rate. The two separate mechanisms, deflection and pulsation, constitute sensing mechanisms for pressure and flow rate. Using the same device architecture, we also detected pressure-induced deformations by a gas to draw further insight into the sensing mechanism of the membrane. Flow rate measurements based on the deformation and instability of thin membranes demonstrate the transduction potential of microwave resonators for fluid-structure interactions at micro- and nanoscales.

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