4.5 Article

Acoustic prison for single live cell 3D multi-imaging enabled by light-sheet microscopy

Related references

Note: Only part of the references are listed.
Article Biophysics

Acoustofluidic multimodal diagnostic system for Alzheimer's disease

Nanjing Hao et al.

Summary: Alzheimer's disease is a severe neurodegenerative disorder with early diagnosis being a challenge. Researchers have developed an integrated diagnostic system combining acoustics, microfluidics, and biosensors for accurate and rapid detection of AD biomarkers, showing promising results for early diagnosis.

BIOSENSORS & BIOELECTRONICS (2022)

Article Biophysics

Acoustofluidic interferometric device for rapid single-cell physical phenotyping

J. Mejia Morales et al.

Summary: High-throughput single-cell analysis based on physical properties is a promising tool for clinical research. This paper introduces a novel microfluidic approach using acoustic waves and interferometry to manipulate and measure the optomechanical properties of single cells.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2022)

Article Engineering, Mechanical

Acoustofluidic Patterning inside Capillary Tubes Using Standing Surface Acoustic Waves

Sadaf Maramizonouz et al.

Summary: Acoustofluidic platforms have the potential to manipulate microparticles and biological cells using capillary tubes. Patterns of microparticles differ between rectangular and circular glass capillary tubes, with particles aligning parallel to the tube walls in rectangular tubes and showing varied alignment at different heights in circular tubes. Continuous liquid flow enhances and smoothens the patterns of particles aligned by acoustic waves.

INTERNATIONAL JOURNAL OF MECHANICAL SCIENCES (2022)

Article Engineering, Electrical & Electronic

Enhanced acoustofluidic mixing in a semicircular microchannel using plate mode coupling in a surface acoustic wave device

Jin-Chen Hsu et al.

Summary: This study presents enhanced acoustic mixing inside a semicircular microfluidic channel using acoustic streaming induced by acoustic plate modes (APMs). By exciting APMs on a 500-μm-thick polished lithium-niobate (LiNbO3) substrate, stronger acoustic streaming flow and stirring effects were observed, leading to rapid and enhanced mixing processes. Finite element simulation and experimental validation were performed to investigate the acoustic process and mixing behaviors. The ability of the device to enhance micromixing using APM frequencies was demonstrated, suggesting the potential for integrated design with surface acoustic waves (SAWs) in a single system. The results also highlight the innovative application of conventional SAW acoustofluidic devices to extended frequency regimes via APMs without altering the substrate thickness and interdigitated transducer (IDT) pitch.

SENSORS AND ACTUATORS A-PHYSICAL (2022)

Article Chemistry, Multidisciplinary

Surface-Acoustic-Wave (SAW) Induced Mixing Enhances the Detection of Viruses: Application to Measles Sensing in Whole Human Saliva with a SAW Lab-On-a-Chip

Matteo Agostini et al.

Summary: Measles is highly infectious, and despite the availability of a vaccine, it remains common in developing countries and sporadic outbreaks occur in developed countries. This study presents a point-of-care biosensing device capable of detecting measles virus in human saliva, with promising results for measles diagnosis and guidance for designing new biosensing systems.

ADVANCED FUNCTIONAL MATERIALS (2022)

Article Engineering, Chemical

Novel Study on the Mixing Mechanism of Active Micromixers Based on Surface Acoustic Waves

Honglin Lv et al.

Summary: This paper investigates the potential mechanism of using surface acoustic waves (SAW) to drive fluid mixing on a microfluidic chip. Through simulations and experiments, it is found that different types of SAW driving result in different mixing effects, with TSAW driving producing a single vortex flow and SSAW driving producing a symmetric double vortex flow. This study contributes to a better understanding of the SAW-driven effect on flow properties of fluids.

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH (2022)

Article Biochemical Research Methods

Acoustofluidic cell micro-dispenser for single cell trajectory control

Cynthia Richard et al.

Summary: This article presents an acoustofluidic micro-dispenser based on surface acoustic waves (SAWs) that can trap and release individual cells and guide their trajectory. The device demonstrates high efficiency in single cell capture and release, making it potentially useful for applications such as single cell fluorescent imaging and proteomic studies.

LAB ON A CHIP (2022)

Article Nanoscience & Nanotechnology

Multiple outcome particle manipulation using cascaded surface acoustic waves (CSAW)

Jia Wei Ng et al.

Summary: Surface acoustic waves (SAW) can generate a sound field in a microfluidic channel to exert forces on suspended particles and cells, enabling selective displacement. Different outcomes can be achieved by using a single SAW source or a pair of sources at different spatial positions to manipulate the particles.

MICROFLUIDICS AND NANOFLUIDICS (2021)

Article Cell Biology

High-throughput multiparametric imaging flow cytometry: toward diffraction-limited sub-cellular detection and monitoring of sub-cellular processes

Gregor Holzner et al.

Summary: This sheathless, microfluidic imaging flow cytometer with stroboscopic illumination achieves blur-free fluorescence detection at ultra-high analytical throughput, quantifying multi-parametric fluorescence and sub-cellular localization at 500 nm resolution. The effectiveness of the approach is demonstrated through analysis and localization of P-bodies and stress granules in yeast and human cells, with throughputs exceeding 60,000 and 400,000 cells/s. The utility of the imaging flow cytometer is highlighted in directly investigating phase-separated compartments within cellular environments and screening rare events at the sub-cellular level for various diagnostic applications.

CELL REPORTS (2021)

Article Biochemical Research Methods

Single-objective high-resolution confocal light sheet fluorescence microscopy for standard biological sample geometries

Stoyan Yordanov et al.

Summary: A single-objective light sheet fluorescence system was developed for biological imaging, utilizing axial plane optical microscopy and digital confocal slit detection to reduce phototoxicity and photobleaching. This system offers similar optical resolution to spinning disk confocal microscopy but significantly reduces photobleaching at the same signal level.

BIOMEDICAL OPTICS EXPRESS (2021)

Review Biotechnology & Applied Microbiology

Image-Based Live Cell Sorting

Cody A. LaBelle et al.

Summary: Single-cell analysis and sorting have revolutionized biomedical research and clinical medicine, allowing for a deeper exploration of cell physiology and behavior. These technologies provide powerful tools for genetic engineering, regenerative medicine, and cancer immunotherapies by enabling more precise cell selection criteria and the creation of cell lines with unique properties.

TRENDS IN BIOTECHNOLOGY (2021)

Article Biochemical Research Methods

Three-dimensional imaging on a chip using optofluidics light-sheet fluorescence microscopy

Erick J. Vargas-Ordaz et al.

Summary: This study integrates light-sheet imaging technology directly into a microfluidic chip, achieving 3D imaging of cells with high resolution, fast imaging speed, and easy integration, demonstrating imaging rates of 120 ms per cell and enabling the extraction of complex cellular phenotypes.

LAB ON A CHIP (2021)

Article Biochemical Research Methods

Dosage-controlled intracellular delivery mediated by acoustofluidics for lab on a chip applications

Alinaghi Salari et al.

Summary: This study presents a novel acoustofluidic strategy for efficient intracellular delivery in adherent cells, using strong mechanical oscillations mediated by Lamb waves in a microfluidic channel. The method achieves successful delivery of cargo materials with high efficiency and shows versatility across different cell lines. It also demonstrates the tunability of dosage control and highlights unique features such as high viability, scalability, portability, and ease of operation.

LAB ON A CHIP (2021)

Article Multidisciplinary Sciences

Image-Based Single Cell Sorting Automation in Droplet Microfluidics

Muhsincan Sesen et al.

SCIENTIFIC REPORTS (2020)

Review Chemistry, Multidisciplinary

Advanced Biological Imaging for Intracellular Micromanipulation: Methods and Applications

Wendi Gao et al.

APPLIED SCIENCES-BASEL (2020)

Article Biotechnology & Applied Microbiology

Automation and flow control for particle manipulation

Dinesh Kumar et al.

CURRENT OPINION IN CHEMICAL ENGINEERING (2020)

Article Biochemical Research Methods

Miniaturized modular-array fluorescence microscopy

Jeonghwan Son et al.

BIOMEDICAL OPTICS EXPRESS (2020)

Article Biochemical Research Methods

Acoustic erythrocytometer for mechanically probing cell viscoelasticity

A. Link et al.

LAB ON A CHIP (2020)

Article Chemistry, Analytical

Focused surface acoustic waves induced microdroplets generation and its application for microgels

Shaobo Jin et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Article Biochemical Research Methods

Traveling surface acoustic wave (TSAW) microfluidic fluorescence activated cell sorter (μFACS)

K. Mutafopulos et al.

LAB ON A CHIP (2019)

Article Biochemical Research Methods

Blood platelet enrichment in mass-producible surface acoustic wave (SAW) driven microfluidic chips

Cynthia Richard et al.

LAB ON A CHIP (2019)

Article Chemistry, Physical

Continuous tuneable droplet ejection via pulsed surface acoustic wave jetting

Jasmine O. Castro et al.

SOFT MATTER (2018)

Editorial Material Biotechnology & Applied Microbiology

Diagnostic Potential of Imaging Flow Cytometry

Minh Doan et al.

TRENDS IN BIOTECHNOLOGY (2018)

Article Multidisciplinary Sciences

3D single-molecule super-resolution microscopy with a tilted light sheet

Anna-Karin Gustavsson et al.

NATURE COMMUNICATIONS (2018)

Article Biochemical Research Methods

Label-free light-sheet microfluidic cytometry for the automatic identification of senescent cells

Meiai Lin et al.

BIOMEDICAL OPTICS EXPRESS (2018)

Article Biochemistry & Molecular Biology

Intelligent Image-Activated Cell Sorting

Nao Nitta et al.

Article Multidisciplinary Sciences

Light Sheet-based Fluorescence Microscopy of Living or Fixed and Stained Tribolium castaneum Embryos

Frederic Strobl et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2017)

Article Biochemical Research Methods

Light-sheet fluorescence microscopy for quantitative biology

Ernst H. K. Stelzer

NATURE METHODS (2015)

Article Multidisciplinary Sciences

Controlling cell-cell interactions using surface acoustic waves

Feng Guo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Chemistry, Analytical

Standing Surface Acoustic Wave Based Cell Coculture

Sixing Li et al.

ANALYTICAL CHEMISTRY (2014)

Editorial Material Anatomy & Morphology

Overview of Live-Cell Imaging: Requirements and Methods Used

Ellen C. Jensen

ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY (2013)

Review Biochemistry & Molecular Biology

Mitochondrial Regulation of Cell Cycle and Proliferation

Valeria Gabriela Antico Arciuch et al.

ANTIOXIDANTS & REDOX SIGNALING (2012)

Article Biochemical Research Methods

Uniform mixing in paper-based microfluidic systems using surface acoustic waves

Amgad R. Rezk et al.

LAB ON A CHIP (2012)

Review Cell Biology

Light sheet microscopy for real-time developmental biology

Michael Weber et al.

CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)

Article Physics, Applied

Hydrodynamic trap for single particles and cells

Melikhan Tanyeri et al.

APPLIED PHYSICS LETTERS (2010)

Article Physics, Applied

Particle concentration and mixing in microdrops driven by focused surface acoustic waves

Richard Shilton et al.

JOURNAL OF APPLIED PHYSICS (2008)

Article Physics, Multidisciplinary

Experimental evidence of absolute and convective instabilities in optics

E Louvergneaux et al.

PHYSICAL REVIEW LETTERS (2004)