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Pseudomonas aeruginosa's greenish-blue pigment pyocyanin: its production and biological activities

Journal

MICROBIAL CELL FACTORIES
Volume 22, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s12934-023-02122-1

Keywords

Bioprospecting; Pseudomonas aeruginosa; Bacterial pigments; Pyocyanin

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The discussion focuses on the bioprospecting of microorganisms and their bioactive byproducts, specifically pigments. Microbial pigments, such as pyocyanin produced by Pseudomonas aeruginosa, have various benefits including their natural composition, therapeutic effects, and year-round production. This article concentrates on the production, extraction, and biological applications of pyocyanin pigment in biotechnology, engineering, and biology fields.
A subject of great interest is the bioprospecting of microorganisms and their bioactive byproducts, such as pigments. Microbial pigments have various benefits, including being safe to use due to their natural makeup, having therapeutic effects, and being produced all year round, regardless of the weather or location. Pseudomonas aeruginosa produces phenazine pigments that are crucial for interactions between Pseudomonas species and other living things. Pyocyanin pigment, which is synthesized by 90-95% of P. aeruginosa, has potent antibacterial, antioxidant, and anticancer properties. Herein, we will concentrate on the production and extraction of pyocyanin pigment and its biological use in different areas of biotechnology, engineering, and biology.

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