Research progress of mechanisms of fat necrosis after autologous fat grafting: A review

Currently, autologous fat grafting is the common surgery employed in the department of plastic and cosmetic surgery. Complications after fat grafting (such as fat necrosis, calcification, and fat embolism) are the difficulties and hotspots of the current research. Fat necrosis is one of the most common complications after fat grafting, which directly affects the survival rate and surgical effect. In recent years, researchers in various countries have achieved great results on the mechanism of fat necrosis through further clinical and basic studies. We summarize recent research progress on fat necrosis in order to provide theoretical basis for diminishing it.

Automated summary

Autologous fat grafting is a common surgical procedure in plastic and cosmetic surgery, but complications such as fat necrosis, calcification, and fat embolism are challenging areas of current research. Fat necrosis, a common complication after fat grafting, directly affects both surgical outcomes and survival rates. In recent years, researchers from various countries have made significant progress in understanding the mechanisms of fat necrosis through clinical and basic studies. We summarize recent research advancements on fat necrosis to provide a theoretical basis for reducing its occurrence.