Copper-doped melanin nanozyme with enhanced photothermal and peroxidase-like catalytic property for synergistic antimicrobial effect

Article Chemistry, Physical

Biomimetic copper single-atom nanozyme system for self-enhanced nanocatalytic tumor therapy

Daoming Zhu et al.

Summary: A biomimetic single-atom nanozyme system was developed for self-enhanced nanocatalytic tumor therapy (NCT) by combining platelet membrane vesicles, a proton pump inhibitor, and copper nanozymes. The system demonstrated good tumor-targeting capabilities and efficient catalytic activity, while also regulating the hydrogen ion, glutathione, and hydrogen peroxide levels in tumor cells to improve therapeutic effect. In vivo studies showed a high tumor suppression rate, and the integration of glutamine metabolism therapy with nanocatalytic tumor therapy provides a novel strategy for multimodal tumor treatment.

NANO RESEARCH (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Bimetallic oxide Cu1.5Mn1.5O4 cage-like frame nanospheres with triple enzyme-like activities for bacterial-infected wound therapy

Konglin Wu et al.

Summary: In this study, bimetallic oxide Cu1.5Mn1.5O4 cage-like nanospheres with a special mesoporous cavity structure were synthesized, exhibiting enhanced triple enzyme-like activities and potential applications in antibacterial therapy and wound disinfection.

NANO TODAY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Single-molecule study of the effects of temperature, pH, and RNA base on the stepwise enzyme kinetics of 10-23 deoxyribozyme

Jiwon Jung et al.

Summary: In this study, we investigated the effects of temperature, pH, and RNA residue on the stepwise enzyme kinetics of 10-23 deoxyribozyme at the single-molecule level. Our findings suggest that temperature and pH significantly affect the enzymatic reaction, while different RNA residues specifically impact the cleavage step.

RSC ADVANCES (2022)

Add to Collection

Review Biotechnology & Applied Microbiology

Multienzymes activity of metals and metal oxide nanomaterials: applications from biotechnology to medicine and environmental engineering

Negar Alizadeh et al.

Summary: Nanozymes, nanomaterials with enzyme-like catalytic activity, have drawn significant attention for their low cost, high stability, and ease of recycling, making them a convenient substitute for natural enzymes in various applications. This review summarizes the latest progress in the applications of metal and metal oxide nanozymes in sensing, cancer therapy, water treatment, and anti-bacterial efficacy, highlighting their potential in disease prevention and diagnostic monitoring for future pandemics.

JOURNAL OF NANOBIOTECHNOLOGY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Nanozymes: A clear definition with fuzzy edges

Hui Wei et al.

NANO TODAY (2021)

Add to Collection

Article Engineering, Biomedical

Copper single-atom catalysts with photothermal performance and enhanced nanozyme activity for bacteria-infected wound therapy

Xianwen Wang et al.

Summary: This study highlights the enhanced catalytic activity of nanozymes through the construction of Cu SASs/NPC for photothermal-catalytic antibacterial treatment strategy. The introduction of Cu significantly improves the catalytic performance of nanozymes, effectively killing bacteria and improving sterilization effect. The synergistic PTT-catalytic antibacterial strategy shows almost 100% antibacterial efficiency against E. coli and MRSA, demonstrating wide bio-applications of Cu-containing catalysts in antibacterial and anti-infective treatments.

BIOACTIVE MATERIALS (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Nanozymes Inspired by Natural Enzymes

Ruofei Zhang et al.

Summary: Nanozymes, nanomaterials with enzyme-like activities, have attracted significant attention in recent years as potential substitutes and competitors for natural enzymes. The key focus in this field is on creating nanozymes with catalytic performance comparable to or surpassing that of natural enzymes. By employing a bioinspired strategy, researchers have successfully synthesized high-activity nanozymes that show similar catalytic activities to natural enzymes, establishing a new hot topic in nanozyme research.

ACCOUNTS OF MATERIALS RESEARCH (2021)

Add to Collection

Article Chemistry, Multidisciplinary