4.2 Article

Sensitivity considerations on denoising series of spectra by singular value decomposition

Journal

MAGNETIC RESONANCE IN CHEMISTRY
Volume -, Issue -, Pages -

Publisher

WILEY
DOI: 10.1002/mrc.5338

Keywords

cross-polarization; denoising; processing; sensitivity; time-efficiency of NMR experiments

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When dealing with samples that have poor signal-to-noise ratio, it is often necessary to choose between taking a few points with a large number of scans to maximize signal-to-noise ratio or more points with a smaller number of scans to maximize information content. In this study, we demonstrate how low-rank decomposition can be utilized to denoise a series of spectra, reducing the trade-off between the number of scans and the number of experiments.
When acquiring series of spectra (T-1, T-2, CP buildup curves, etc.) on samples with poor SNR, we are usually faced with choosing between taking a few points with a large number of scans to maximize the SNR or more points with a smaller number of scans to maximize the information content. In this Letter, we show how low-rank decomposition can be used to denoise a series of spectra, reducing the trade-off between the number of scans and the number of experiments.

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