☆ 4.7 Review

Advances in Intelligent Stimuli-Responsive Microneedle for Biomedical Applications

MACROMOLECULAR BIOSCIENCE (2023)

Related references

Note: Only part of the references are listed.

Article Chemistry, Multidisciplinary

Supramolecular Loading of DNA Hydrogels with Dye-Drug Conjugates for Real-Time Photoacoustic Monitoring of Chemotherapy

Raina M. M. Borum et al.

Summary: This work describes an injectable supramolecular hydrogel that allows slow and trackable release of doxorubicin via photoacoustic tomography. The hydrogel exhibits good biodegradability, maintains long-term contrast in live tissue, and demonstrates activatable photoacoustic spectral shifts during degradation.

ADVANCED SCIENCE (2023)

Add to Collection

Article Engineering, Environmental

Flav7+DOX co-loaded separable microneedle for light-triggered chemo-thermal therapy of superficial tumors

Huixin Wang et al.

Summary: This study presented a novel microneedle system loaded with the multipurpose small molecule Flav7 for high-efficiency light-activated drug release for chemotherapy and high-performance light-controlled thermotherapy of tumors, as well as remarkable NIR-II fluorescence imaging to guide chemo-thermal therapy.

CHEMICAL ENGINEERING JOURNAL (2022)

Add to Collection

Article Polymer Science

Polymer Vesicles with Upper Critical Solution Temperature for Near-infrared Light-triggered Transdermal Delivery of Metformin in Diabetic Rats

Wei Hu et al.

Summary: A NIR-triggered microneedle (MN) patch array with NIR-triggered and temperature responsive drug release behavior has been developed. The device shows significant hypoglycemic effect in diabetic rats, reducing blood glucose concentration to normal levels for several hours.

CHINESE JOURNAL OF POLYMER SCIENCE (2022)

Add to Collection

Article Chemistry, Physical

On-demand transdermal insulin delivery system for type 1 diabetes therapy with no hypoglycemia risks

Yun Fu et al.

Summary: Diabetes poses a significant challenge due to the need for timely insulin administration and consistent blood glucose regulation to reduce the risk of hypoglycemia. The research introduced an insulin delivery system with a glucose sensitive responsive linker for controlled insulin release under high glucose concentrations, ensuring prolonged blood glucose regulation. This system, combined with a hyaluronic-acid based microneedle patch, showed efficient in vivo glucose regulation either through subcutaneous injection or transdermal delivery.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

Add to Collection

Article Materials Science, Biomaterials

Light-regulated nitric oxide release from hydrogel-forming microneedles integrated with graphene oxide for biofilm-infected-wound healing

Chi Juan Ma et al.

Summary: This study proposes a new type of hydrogelforming microneedle that can release nitric oxide (NO) in a mild and controlled manner, resulting in enhanced wound healing by disrupting biofilms and releasing NO directly into the wound.

BIOMATERIALS ADVANCES (2022)

Add to Collection

Article Engineering, Biomedical

Personalized and Programmable Microneedle Dressing for Promoting Wound Healing

Yuqiu Wang et al.

Summary: Researchers have developed a novel microneedle wound dressing with superfine needle tips, personalized pattern design, and programmable features for intelligent and painless drug delivery. By using intelligent image recognition and temperature-responsive hydrogel, precise treatment for irregular wounds can be achieved. The dressing also incorporates a controllable drug release system, demonstrating its value in wound management.

ADVANCED HEALTHCARE MATERIALS (2022)

Add to Collection

Article Materials Science, Biomaterials

A theranostic microneedle array patch for integrated glycemia sensing and self-regulated release of insulin

Xuetong Sun et al.

Summary: This study describes a therapeutic and diagnostic microneedle array patch that can visualize and quantify blood glucose levels in real-time, while simultaneously releasing insulin. This offers a promising alternative for improving the quality of life for diabetic patients.

BIOMATERIALS SCIENCE (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Porous MOF Microneedle Array Patch with Photothermal Responsive Nitric Oxide Delivery for Wound Healing

Shun Yao et al.

Summary: A novel porous metal-organic framework (MOF) microneedle (MN) patch enabling photothermal-responsive nitric oxide (NO) delivery for promoting diabetic wound healing is presented. The NO-loadable copper-benzene-1,3,5-tricarboxylate (HKUST-1) MOF encapsulated with graphene oxide (GO) facilitates controlled release of NO molecules, resulting in accelerated vascularization, tissue regeneration, and collagen deposition in diabetic wound healing.

ADVANCED SCIENCE (2022)

Add to Collection

Article Chemistry, Physical

Innovative transdermal delivery of insulin using gelatin methacrylate-based microneedle patches in mice and mini-pigs

Bilal Demir et al.

Summary: Through engineering non-dissolving microneedle arrays and incorporating MoS2 nanosheets as a photothermal component into hydrogels, on-demand release of macromolecular therapeutic drugs such as insulin has been achieved for skin penetration and therapeutic purposes. This system successfully reduced blood glucose levels in mice and pigs, potentially altering current insulin therapies.

NANOSCALE HORIZONS (2022)

Add to Collection

Article Nanoscience & Nanotechnology

Smart Composite Microneedle Patch Stabilizes Glucagon and Prevents Nocturnal Hypoglycemia: Experimental Studies and Molecular Dynamics Simulation

Brian Lu et al.

Summary: Glucagon smart patch has been developed to stabilize and sense hypoglycemia, delivering glucagon automatically to prevent nocturnal hypoglycemia and hypoglycemia unawareness in diabetic patients.

ACS APPLIED MATERIALS & INTERFACES (2022)

Add to Collection

Article Engineering, Biomedical

A wearable gamma radiation-responsive granulocyte colony-stimulating factor microneedle system protecting against ionizing radiation-induced injury

Xiang Yu et al.

Summary: The study developed a wearable system that can monitor gamma radiation and release G-CSF medication immediately to protect against ionizing radiation-induced injury. The system shows promising potential in the field of emergent ionizing radiation injury.

ACTA BIOMATERIALIA (2022)

Add to Collection

Article Engineering, Environmental

Acid-responsive PEGylated branching PLGA nanoparticles integrated into dissolving microneedles enhance local treatment of arthritis

Hongmei Hu et al.

Summary: By designing PEGylated star-shaped PLGA nanoparticles with immune stealth and acid-responsive properties, the drug-loading ability and release efficiency of tetrandrine (Tet) were significantly improved. Furthermore, the integration of these nanoparticles into dissolving microneedles resulted in enhanced transdermal delivery and potential therapeutic efficacy for anti-inflammation treatment.

CHEMICAL ENGINEERING JOURNAL (2022)

Add to Collection

Article Chemistry, Multidisciplinary

A bispecific nanomodulator to potentiate photothermal cancer immunotherapy

Lei Zhou et al.

Summary: A bispecific nanomodulator is developed to trigger photothermal therapy and dual-block PD-L1 and IDO-1 pathways for boosting effective antitumor immunity.

NANO TODAY (2022)

Add to Collection

Article Chemistry, Multidisciplinary

Micro-Gel Ensembles for Accelerated Healing of Chronic Wound via pH Regulation

Tingting Cui et al.

Summary: This work presents a microfluidic assembly technique to fabricate micro-gel ensembles that can precisely tune the pH value of wound surface and accelerate wound healing. By regulating the wound pH, the physiological processes are greatly facilitated, resulting in much accelerated healing of chronic wounds.

ADVANCED SCIENCE (2022)

Add to Collection

Article Chemistry, Physical

Ferroferric oxide loaded near-infrared triggered photothermal microneedle patch for controlled drug release

Jiuyu Cui et al.

Summary: A Fe3O4-loaded photothermal microneedle patch (Fe3O4@MN) has been developed for controlled drug delivery, achieving enhanced drug release efficiency. The Fe3O4@MN has sufficient mechanical strength to penetrate the skin, and its temperature can rapidly increase under NIR irradiation. In vitro experiments showed high drug release rates and increased penetration depth compared to a patch without Fe3O4 nanoparticles, indicating the potential application of the synthesized microneedle patch for transdermal drug delivery.

JOURNAL OF COLLOID AND INTERFACE SCIENCE (2022)

Add to Collection

Review Cell & Tissue Engineering

Application of microneedle patches for drug delivery; doorstep to novel therapies

Fateme Nazary Abrbekoh et al.

Summary: This article summarizes the recent achievements of controllable drug delivery systems (microneedle patches) in vitro and in vivo settings, and discusses the influence of delivered drugs on cellular mechanisms and immunization molecular signaling pathways through the intradermal delivery route.

JOURNAL OF TISSUE ENGINEERING (2022)

Add to Collection

Article Materials Science, Biomaterials

Responsive hydrogel-based microneedle dressing for diabetic wound healing

Zhaoyang Guo et al.

Summary: In this study, a glucose-responsive insulin-releasing hydrogel microneedle dressing was developed for diabetic wound healing. The microneedle dressing exhibited mechanical stability, biocompatibility, glucose-responsive insulin release, and improved blood glucose control, making it effective for diabetic wound management and potentially useful for other chronic skin injuries.

JOURNAL OF MATERIALS CHEMISTRY B (2022)

Add to Collection

Article Polymer Science

A Porous Reservoir-Backed Boronate Gel Microneedle for Efficient Skin Penetration and Sustained Glucose-Responsive Insulin Delivery

Siyuan Chen et al.

Summary: This article describes a novel polyvinyl alcohol-coated microneedle patch with an interconnected porous gel drug reservoir for enhanced skin penetration efficiency and mechanical strength. Compared to other microneedle patches, this new type of patch has stronger skin penetration ability and can achieve on-demand, long-acting transdermal insulin delivery.

GELS (2022)

Add to Collection

Article Engineering, Environmental

Thermo and light-responsive strategies of smart titanium-containing composite material surface for enhancing bacterially anti-adhesive property

Jing Lin et al.

Summary: This study focused on designing a composite material surface with smart response to adjust and enhance bacterial anti-adhesion by thermo and light-responsive strategies. The composite surface was demonstrated to greatly reduce bacterial adhesion by incorporating long-lasting antibacterial and hydrophilic constituents. The durable properties of antibacterial and bacterial anti-adhesive effects make it suitable for applications in mutable environments.

CHEMICAL ENGINEERING JOURNAL (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Intelligent Silk Fibroin Based Microneedle Dressing (i-SMD)

Bingbing Gao et al.

Summary: The i-SMD is an intelligent dressing with drug release and biochemical analysis capabilities, showing promise in facilitating wound healing.

ADVANCED FUNCTIONAL MATERIALS (2021)

Add to Collection

Article Engineering, Environmental

Transdermal delivery of Cu-doped polydopamine using microneedles for photothermal and chemodynamic synergistic therapy against skin melanoma

Gao Song et al.

Summary: This study developed a microneedle system for photothermal and chemodynamic synergistic therapy using Cu-PDA NPs, which effectively inhibited tumor cell proliferation and induced necrosis and apoptosis of tumor cells. The minimally invasive delivery of this multimodal nanoformulation offers a new avenue for the treatment of skin melanoma.

CHEMICAL ENGINEERING JOURNAL (2021)

Add to Collection

Article Engineering, Environmental

Dynamically capped hierarchically porous microneedles enable post-fabrication loading and self-regulated transdermal delivery of insulin

Samira Gholami et al.

Summary: The study developed a smart microneedle system that can respond quickly and repetitively to glucose fluctuations, regulating insulin release in short 40-minute intervals. Application of this system led to rapid achievement of normoglycemia within 1 hour in diabetic mice, lasting for 5 hours. This cap doffing approach shows promise for the development of safe and long-lasting microneedle systems for smart transdermal delivery of insulin and other drugs.

CHEMICAL ENGINEERING JOURNAL (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Hydrogel-Forming Microneedles: Current Advancements and Future Trends

Joseph G. Turner et al.

Summary: Hydrogel-forming microneedles offer enhanced transdermal drug delivery effectiveness and potential for passive extraction of interstitial fluid from the skin, making them suitable for biocompatible minimally invasive monitoring devices.

MACROMOLECULAR BIOSCIENCE (2021)

Add to Collection

Article Chemistry, Physical

Microneedle-array patch with pH-sensitive formulation for glucose-responsive insulin delivery

Feng-Qin Luo et al.

Summary: The study presents a novel glucose-responsive insulin delivery system using pH-sensitive insulin-loaded nanoparticles and glucose oxidase-catalase-loaded pH-insensitive nanoparticles. This system effectively regulates blood glucose levels within normal ranges for a prolonged period and reduces inflammation risks towards normal skin.

NANO RESEARCH (2021)

Add to Collection

Review Engineering, Biomedical

Noble Metal Nanomaterials for NIR-Triggered Photothermal Therapy in Cancer

Zhuoqian Lv et al.

Summary: Developing anticancer therapeutic agents or technologies with high specificity, patient compliance, and low toxicity is important. Noble metal nanomaterials present strong potential for cancer treatment through photothermal therapy, with the ability to achieve multifunctional cancer therapy when combined with various functional reagents.

ADVANCED HEALTHCARE MATERIALS (2021)

Add to Collection

Article Engineering, Biomedical

Microneedle patch for the ultrasensitive quantification of protein biomarkers in interstitial fluid

Zheyu Wang et al.

Summary: Microneedle patches enable rapid sampling and on-needle quantification of target protein biomarkers in interstitial fluid, offering a new possibility for early disease diagnosis.

NATURE BIOMEDICAL ENGINEERING (2021)

Add to Collection

Review Endocrinology & Metabolism

'Smart' insulin-delivery technologies and intrinsic glucose-responsive insulin analogues

Mark A. Jarosinski et al.

Summary: Insulin replacement therapy for diabetes aims to minimize blood glucose fluctuations using smart systems or insulin analogues that provide hormone activity proportional to blood glucose levels. Current strategies for optimization include coupling continuous glucose monitoring with delivery devices, glucose-responsive polymer encapsulation of insulin, and mechanism-based hormone modifications.

DIABETOLOGIA (2021)

Add to Collection

Article Pharmacology & Pharmacy

Microneedles for Extended Transdermal Therapeutics: A Route to Advanced Healthcare

Suman Pahal et al.

Summary: This review discusses the recent advances in microneedle-based devices for sustained release of vaccines, hormones, and antiretrovirals, emphasizing the importance of designing slow-degrading polymeric matrices or providing physiochemical triggers for on-demand drug release. These long-acting transdermal devices help prevent burst release of drugs, ensuring efficient drug delivery.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2021)

Add to Collection

Article Pharmacology & Pharmacy

Introduction of a model of skin lesions on rats and testing of dissolving microneedles containing 5-aminolevulinic acid

Mathilde Champeau et al.

Summary: Topical photodynamic therapy (PDT) is commonly used for treating non melanoma skin cancers, but its effectiveness is limited by the penetration depth of the prodrug. To address this issue, dissolving microneedles included in a patch were developed and shown to be effective in an in vivo rat skin lesion model.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2021)

Add to Collection

Article Chemistry, Analytical

Microneedle array with a pH-responsive polymer coating and its application in smart drug delivery for wound healing

Asad Ullah et al.

Summary: In order to successfully treat wounds, therapeutics must be delivered directly to the wound. However, barriers such as necrotic tissue and biofilms make it challenging to efficiently deliver antibiotics to wounds. By utilizing porous polymer coatings on microneedles for automatic release of therapeutics in response to wound pH conditions, researchers were able to significantly enhance therapeutic results for wound infections.

SENSORS AND ACTUATORS B-CHEMICAL (2021)

Add to Collection

Review Engineering, Biomedical

Lab under the Skin: Microneedle Based Wearable Devices

Hazhir Teymourian et al.

Summary: The latest trend in wearable devices is the development of microneedle-based transdermal sensors for real-time monitoring of health parameters at the molecular level. These sensors offer the advantages of extracting clinical indicators from interstitial fluid and painless skin pricking. The future focus is on assembling electrochemical biosensors on microneedles for direct continuous chemical measurements and overcoming existing challenges in commercializing these innovative products.

ADVANCED HEALTHCARE MATERIALS (2021)

Add to Collection

Article Materials Science, Multidisciplinary

Polymer-grafted hollow mesoporous silica nanoparticles integrated with microneedle patches for glucose-responsive drug delivery

Yaping Wang et al.

Summary: A glucose-responsive drug delivery system has been developed, which can intelligently release drugs based on blood glucose levels. It was shown to have an effective hypoglycemic effect when administered transdermally to diabetic rats, indicating potential application in diabetes treatment.

FRONTIERS OF MATERIALS SCIENCE (2021)

Add to Collection

Article Pharmacology & Pharmacy

Live Vaccinia Virus-Coated Microneedle Array Patches for Smallpox Vaccination and Stockpiling

In-Jeong Choi et al.

Summary: This study examined the feasibility of microneedle-based smallpox vaccination as an alternative approach for stockpiling smallpox vaccines. The results showed that microneedle-based vaccination elicited immune responses in mice and improved the stability of the smallpox vaccine.

PHARMACEUTICS (2021)

Add to Collection

Article Polymer Science

Glucose-responsive hydrogel-based microneedles containing phenylborate ester bonds and N-isopropylacrylamide moieties and their transdermal drug delivery properties

Di Shen et al.

Summary: The phenylboronic acid-based hydrogel microneedle patch with glucose responsiveness and excellent biocompatibility demonstrates self-regulated drug releasing behaviors for improving the treatment quality of diabetics. The reversible phenylborate ester crosslinking points in the hydrogel enhance mechanical strength for skin insertion, laying the foundation for a sensitive, safe, and stable transdermal drug delivery system.

EUROPEAN POLYMER JOURNAL (2021)

Add to Collection

Review Pharmacology & Pharmacy

Stimuli-Responsive Polymers for Transdermal, Transmucosal and Ocular Drug Delivery

Dmitriy Berillo et al.

Summary: Despite the conventional use of oral and intravenous routes for drug administration, they face limitations such as reduced bioavailability and invasiveness. Therefore, alternative delivery routes and modifications to drug formulations using stimuli-responsive polymers can improve drug release and bioavailability.

PHARMACEUTICS (2021)

Add to Collection

Review Chemistry, Multidisciplinary

Near-infrared photoactivated nanomedicines for photothermal synergistic cancer therapy

Haitao Sun et al.

Summary: Cancer nanomedicines offer promising treatment strategies, with photothermal therapy identified as a safe modality for achieving photothermal synergistic cancer therapy and significantly improved benefits.

NANO TODAY (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Shark Tooth-Inspired Microneedle Dressing for Intelligent Wound Management

Maoze Guo et al.

Summary: Intelligent wound management beyond therapeutic drug treatment shows potential in promoting recovery from chronic wounds. A shark tooth-inspired microneedle patch was developed using biomimetic structures for stable adhesion, controlled drug release, and analysis of inflammatory factors, as well as sensitive motion monitoring with MXene electronics, demonstrating improved recovery for full-thickness cutaneous wounds.

ACS NANO (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Magneto-Responsive Microneedle Robots for Intestinal Macromolecule Delivery

Xiaoxuan Zhang et al.

Summary: The novel magneto-responsive microneedle robots are designed for efficient oral delivery of versatile macromolecules. With polarized magnetic substrate, the microneedle tips can target the small intestinal wall, insert into the tissue, and release encapsulated actives under specific magnetic fields, demonstrating practical values in oral delivery of insulin and blood glucose regulation.

ADVANCED MATERIALS (2021)

Add to Collection

Review Biochemistry & Molecular Biology

Strategies to Develop a Suitable Formulation for Inflammatory Skin Disease Treatment

Jiun-Wen Guo et al.

Summary: The treatment of inflammatory skin diseases poses challenges, with topical therapy being the first line of management. The key to success lies in the effectiveness and adaptability of the pharmaceutical formulation.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Add to Collection

Article Materials Science, Biomaterials

Cross-Linking-Density-Changeable Microneedle Patch Prepared from a Glucose-Responsive Hydrogel for Insulin Delivery

Xiang Chen et al.

Summary: A glucose-responsive microneedle patch was designed with changeable cross-linking density, allowing for insulin release triggered by glucose. The mechanical strength of the patch was enhanced by crystallizing PVA chains through freezing and thawing. The patch effectively pierced the skin and slowly released insulin in hypoglycemic experiments with diabetic rats.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Microneedle Patch Prepared from a Hydrogel by a Mild Method for Insulin Delivery

Xiang Chen et al.

Summary: A novel gel was developed based on the reversibility of boronate ester bond, which enabled the loading of insulin for a glucose-responsive delivery system. The microneedle patches showed great potential in maintaining normal blood glucose levels in diabetic rats, indicating a promising future for mass production.

CHEMNANOMAT (2021)

Add to Collection

Article Multidisciplinary Sciences

MXene-Integrated Microneedle Patches with Innate Molecule Encapsulation for Wound Healing

Lingyu Sun et al.

Summary: This study proposes a novel method utilizing MXene-integrated microneedle patches with adenosine encapsulation for wound healing. The results demonstrate that these patches have a significant effect on promoting angiogenesis.

RESEARCH (2021)

Add to Collection

Article Materials Science, Biomaterials

A carbonized wormwood modified photothermal microneedle patch for the repair of damaged skeletal muscles

Chuxi Zhang et al.

Summary: The study focused on efficient repair of damaged skeletal muscles using polyvinyl alcohol soluble microneedle patches loaded with carbonized wormwood and prostaglandin E2. Experimental results showed quicker restoration of muscle strength and fiber cross-sectional area, as well as successful induction of stem cell proliferation and differentiation for effective muscle tissue repair. Overall, this light-controlled photothermal microneedle drug-delivery system provided a safe, accurate, and efficient approach for treating skeletal muscle damage using carbonized wormwood.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Materials Science, Biomaterials

Biodegradable phenylboronic acid-modified ε-polylysine for glucose-responsive insulin delivery via transdermal microneedles

Di Shen et al.

Summary: Glucose-responsive particles were synthesized with good biocompatibility and pharmacokinetics, showing potential for controlled insulin delivery. The self-assembled particles demonstrated glucose-responsive insulin delivery performance in vitro.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Materials Science, Biomaterials

Polyvinyl alcohol/chitosan composite hydrogels with sustained release of traditional Tibetan medicine for promoting chronic diabetic wound healing

Zuxin Wang et al.

Summary: The study demonstrates that TEP-loaded hydrogels have significant anti-inflammatory and wound healing effects, are non-toxic to cells, and are suitable for treating diabetic wounds.

BIOMATERIALS SCIENCE (2021)

Add to Collection

Article Materials Science, Biomaterials

A dissolving and glucose-responsive insulin-releasing microneedle patch for type 1 diabetes therapy

Yujie Zhang et al.

Summary: The study developed a dissolving and glucose-responsive insulin-releasing microneedle patch system for minimally invasive and glucose-responsive insulin delivery for type 1 diabetes therapy. The system effectively regulated blood glucose levels in mice for 1-2 days and alleviated diabetic symptoms in type 1 diabetic mice.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Materials Science, Biomaterials

An accurate and dual-effective body slimming method through a soluble microneedle patch with variable temperature

Haichuan Peng et al.

Summary: The combination of microneedle patches, melanin, photothermal effects, and external cold stimulation provides a promising nonsurgical method for achieving significant and precise body slimming effects in the future.

JOURNAL OF MATERIALS CHEMISTRY B (2021)

Add to Collection

Article Chemistry, Multidisciplinary

Glucose-Responsive Nanoparticles for Rapid and Extended Self-Regulated Insulin Delivery

Lisa R. Volpatti et al.

ACS NANO (2020)

Add to Collection

Article Pharmacology & Pharmacy

Enhancement in site-specific delivery of carvacrol for potential treatment of infected wounds using infection responsive nanoparticles loaded into dissolving microneedles: A proof of concept study

Maria Mir et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2020)

Add to Collection

Review Engineering, Electrical & Electronic

A Mini Review of Microneedle Array Electrode for Bio-Signal Recording: A Review

Lei Ren et al.

IEEE SENSORS JOURNAL (2020)

Add to Collection

Article Engineering, Biomedical

Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs

Jicheng Yu et al.

NATURE BIOMEDICAL ENGINEERING (2020)

Add to Collection

Article Engineering, Biomedical

Transdermal colorimetric patch for hyperglycemia sensing in diabetic mice

Zejun Wang et al.

BIOMATERIALS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

pH-sensitive MOF integrated with glucose oxidase for glucose-responsive insulin delivery

Cheng Zhang et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Add to Collection

Article Pharmacology & Pharmacy

Engineering of Nanospheres Dispersed Microneedle System for Antihypertensive Action

Mrunmayi Sardesai et al.

CURRENT DRUG DELIVERY (2020)

Add to Collection

Article Pharmacology & Pharmacy

A facile fabrication of dissolving microneedles containing 5-aminolevulinic acid

Mathilde Champeau et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Add to Collection

Article Pharmacology & Pharmacy

Smart Microneedles with Porous Polymer Layer for Glucose-Responsive Insulin Delivery

Asad Ullah et al.

PHARMACEUTICS (2020)

Add to Collection

Article Materials Science, Multidisciplinary

Black phosphorus modified soluble microneedle patch for painless, effective and accurate body slimming

Haichuan Peng et al.

Applied Materials Today (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Construction of microneedle-assisted co-delivery platform and its combining photodynamic/immunotherapy

Shi-Xiong Chen et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Add to Collection

Article Engineering, Biomedical

Antibacterial and angiogenic chitosan microneedle array patch for promoting wound healing

Junjie Chi et al.

BIOACTIVE MATERIALS (2020)

Add to Collection

Article Engineering, Environmental

On-skin glucose-biosensing and on-demand insulin-zinc hexamers delivery using microneedles for syringe-free diabetes management

Wen-Lin Hsu et al.

CHEMICAL ENGINEERING JOURNAL (2020)

Add to Collection

Article Pharmacology & Pharmacy

Customized fast-separable microneedles prepared with the aid of 3D printing for nanoparticle delivery

Nesma El-Sayed et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Stimulus-responsive sequential release systems for drug and gene delivery

Sepideh Ahmadi et al.

NANO TODAY (2020)

Add to Collection

Review Chemistry, Multidisciplinary

Wearable Electrochemical Sensors for the Monitoring and Screening of Drugs

Hazhir Teymourian et al.

ACS SENSORS (2020)

Add to Collection

Article Engineering, Biomedical

Near-infrared responsive 5-fluorouracil and indocyanine green loaded MPEG-PCL nanoparticle integrated with dissolvable microneedle for skin cancer therapy

Ying Hao et al.

BIOACTIVE MATERIALS (2020)

Add to Collection

Article Materials Science, Biomaterials

Assisted 3D printing of microneedle patches for minimally invasive glucose control in diabetes

Mingxin Wu et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Colloidal crystal microneedle patch for glucose monitoring

Yi Zeng et al.

NANO TODAY (2020)

Add to Collection

Article Nanoscience & Nanotechnology

Glucose-Responsive Gold Nanocluster-Loaded Microneedle Patch for Type 1 Diabetes Therapy

Yujie Zhang et al.

ACS APPLIED BIO MATERIALS (2020)

Add to Collection

Article Multidisciplinary Sciences

Dual self-regulated delivery of insulin and glucagon by a hybrid patch

Zejun Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function

Samuel Babity et al.

JOURNAL OF CONTROLLED RELEASE (2020)

Add to Collection

Article Engineering, Biomedical

Active delivery of multi-layer drug-loaded microneedle patches using magnetically driven capsule

Jihun Lee et al.

MEDICAL ENGINEERING & PHYSICS (2020)

Add to Collection

Article Materials Science, Biomaterials

Dissolving microneedles integrated with pH-responsive micelles containing AIEgen with ultra-photostability for enhancing melanoma photothermal therapy

Sihui Wei et al.

BIOMATERIALS SCIENCE (2020)

Add to Collection

Article Nanoscience & Nanotechnology

Glucose- and pH-Responsive Supramolecular Polymer Vesicles Based on Host-Guest Interaction for Transcutaneous Delivery of Insulin

Yonghui Lin et al.

ACS APPLIED BIO MATERIALS (2020)

Add to Collection

Article Materials Science, Biomaterials

Rapidly dissolving microneedle patch for synergistic gene and photothermal therapy of subcutaneous tumor

Qinan Xu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Add to Collection

Article Materials Science, Multidisciplinary

Temperature-Stable Boronate Gel-Based Microneedle Technology for Self-Regulated Insulin Delivery

Siyuan Chen et al.

ACS APPLIED POLYMER MATERIALS (2020)

Add to Collection

Article Materials Science, Biomaterials

Plasmonic photothermal microneedle arrays and single needles for minimally-invasive deep in-skin hyperthermia

Alvaro Carcamo-Martinez et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Add to Collection

Article Astronomy & Astrophysics

The Effects of Dust Optical Properties on the Scattering-induced Disk Polarization by Millimeter-sized Grains

Haifeng Yang et al.

ASTROPHYSICAL JOURNAL (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Development of a Minimally Invasive Microneedle-Based Sensor for Continuous Monitoring of β-Lactam Antibiotic Concentrations in Vivo

Sally A. N. Gowers et al.

ACS SENSORS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Glucose-Responsive Composite Microneedle Patch for Hypoglycemia-Triggered Delivery of Native Glucagon

Amin GhavamiNejad et al.

ADVANCED MATERIALS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Encoded Microneedle Arrays for Detection of Skin Interstitial Fluid Biomarkers

Xiaoxuan Zhang et al.

ADVANCED MATERIALS (2019)

Add to Collection

Article Materials Science, Biomaterials

Smart Microneedle Fabricated with Silk Fibroin Combined Semi interpenetrating Network Hydrogel for Glucose-Responsive Insulin Delivery

Siyuan Chen et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2019)

Add to Collection

Article Multidisciplinary Sciences

Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs

Jinqiang Wang et al.

SCIENCE ADVANCES (2019)

Add to Collection

Article Nanoscience & Nanotechnology

Hyaluronic Acid-Based Dissolving Microneedle Patch Loaded with Methotrexate for Improved Treatment of Psoriasis

Hongyao Du et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Cutaneous microenvironment responsive microneedle patch for rapid gene release to treat subdermal tumor

Xinfang Li et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Add to Collection

Article Chemistry, Analytical

Controlled transdermal drug delivery using a wireless magnetic microneedle patch: Preclinical device development

V. R. Jayaneththi et al.

SENSORS AND ACTUATORS B-CHEMICAL (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Microneedle-Array Patch Fabricated with Enzyme-Free Polymeric Components Capable of On-Demand Insulin Delivery

Siyuan Chen et al.

ADVANCED FUNCTIONAL MATERIALS (2019)

Add to Collection

Article Engineering, Biomedical

5-Aminolevulinic Acid-Loaded Hyaluronic Acid Dissolving Microneedles for Effective Photodynamic Therapy of Superficial Tumors with Enhanced Long-Term Stability

Jinjin Zhu et al.

ADVANCED HEALTHCARE MATERIALS (2019)

Add to Collection

Article Materials Science, Biomaterials

Thermal ablation of separable microneedles for transdermal delivery of metformin on diabetic rats

Yang Zhang et al.

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS (2019)

Add to Collection

Review Chemistry, Multidisciplinary

Polymeric microneedles for controlled transdermal drug delivery

Parbeen Singh et al.

JOURNAL OF CONTROLLED RELEASE (2019)

Add to Collection

Article Plant Sciences

The fluorescent protein sensor roGFP2-Orp1 monitors in vivo H2O2 and thiol redox integration and elucidates intracellular H2O2 dynamics during elicitor-induced oxidative burst in Arabidopsis

Thomas Nietzel et al.

NEW PHYTOLOGIST (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Design and Applications of Photoresponsive Hydrogels

Lei Li et al.

ADVANCED MATERIALS (2019)

Add to Collection

Article Chemistry, Multidisciplinary

Glucose Oxidase-Instructed Multimodal Synergistic Cancer Therapy

Lian-Hua Fu et al.

ADVANCED MATERIALS (2019)

Add to Collection

Review Chemistry, Physical

Microneedle-based electrochemical devices for transdermal biosensing: a review

Federico Tasca et al.

CURRENT OPINION IN ELECTROCHEMISTRY (2019)

Add to Collection

Article Materials Science, Biomaterials

Poly(cystine-PCL) based pH/redox dual-responsive nanocarriers for enhanced tumor therapy

Xinyu Zhang et al.

BIOMATERIALS SCIENCE (2019)

Add to Collection

Article Materials Science, Biomaterials

Microneedles combined with a sticky and heatable hydrogel for local painless anesthesia

Feng Zhang et al.

BIOMATERIALS SCIENCE (2019)

Add to Collection

Article Engineering, Biomedical

Advances in Stimulus-Responsive Polymeric Materials for Systemic Delivery of Nucleic Acids

Minjie Sun et al.

ADVANCED HEALTHCARE MATERIALS (2018)

Add to Collection

Article Nanoscience & Nanotechnology

Glucose- and H2O2-Responsive Polymeric Vesicles Integrated with Microneedle Patches for Glucose-Sensitive Transcutaneous Delivery of Insulin in Diabetic Rats

Zaizai Tong et al.

ACS APPLIED MATERIALS & INTERFACES (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery

Jinqiang Wang et al.

ACS NANO (2018)

Add to Collection

Article Chemistry, Analytical

A pilot study in humans of microneedle sensor arrays for continuous glucose monitoring

Sanjiv Sharma et al.

ANALYTICAL METHODS (2018)

Add to Collection

Review Chemistry, Multidisciplinary

Development of endogenous enzyme-responsive nanomaterials for theranostics

Jing Mu et al.

CHEMICAL SOCIETY REVIEWS (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Microneedle arrays coated with charge reversal pH-sensitive copolymers improve antigen presenting cells-homing DNA vaccine delivery and immune responses

Huu Thuy Trang Duong et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Bioresponsive Microneedles with a Sheath Structure for H2O2 and pH Cascade-Triggered Insulin Delivery

Yuqi Zhang et al.

SMALL (2018)

Add to Collection

Article Biology

Multifunctional chitosan-magnetic graphene quantum dot nanocomposites for the release of therapeutics from detachable and non-detachable biodegradable microneedle arrays

Richard Justin et al.

INTERFACE FOCUS (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Synthesis and Characterization of Lignin Hydrogels for Potential Applications as Drug Eluting Antimicrobial Coatings for Medical Materials

Eneko Larraneta et al.

ACS SUSTAINABLE CHEMISTRY & ENGINEERING (2018)

Add to Collection

Article Materials Science, Biomaterials

Separable Microneedles for Near-Infrared Light-Triggered Transdermal Delivery of Metformin in Diabetic Rats

Yang Zhang et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)

Add to Collection

Article Materials Science, Biomaterials

Separable Microneedles for Near-Infrared Light-Triggered Transdermal Delivery of Metformin in Diabetic Rats

Yang Zhang et al.

ACS BIOMATERIALS SCIENCE & ENGINEERING (2018)

Add to Collection

Article Engineering, Biomedical

Smart vaccine delivery based on microneedle arrays decorated with ultra-pH-responsive copolymers for cancer immunotherapy

Huu Thuy Trang Duong et al.

BIOMATERIALS (2018)

Add to Collection

Article Nanoscience & Nanotechnology

Polymeric Microneedles Integrated with Metformin-Loaded and PDA/LA-Coated Hollow Mesoporous SiO2 for NIR-Triggered Transdermal Delivery on Diabetic Rats

Yang Zhang et al.

ACS APPLIED BIO MATERIALS (2018)

Add to Collection

Article Pharmacology & Pharmacy

ROS-Responsive Microneedle Patch for Acne Vulgaris Treatment

Yuqi Zhang et al.

ADVANCED THERAPEUTICS (2018)

Add to Collection

Article Pharmacology & Pharmacy

Near-Infrared Responsive PEGylated Gold Nanorod and Doxorubicin Loaded Dissolvable Hyaluronic Acid Microneedles for Human Epidermoid Cancer Therapy

Ying Hao et al.

ADVANCED THERAPEUTICS (2018)

Add to Collection

Article Chemistry, Multidisciplinary

Thrombin-Responsive Transcutaneous Patch for Auto-Anticoagulant Regulation

Yuqi Zhang et al.

ADVANCED MATERIALS (2017)

Add to Collection

Article Medicine, General & Internal

Association of Insulin Pump Therapy vs Insulin Injection Therapy With Severe Hypoglycemia, Ketoacidosis, and Glycemic Control Among Children, Adolescents, and Young Adults With Type 1 Diabetes

Beate Karges et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2017)

Add to Collection

Review Nanoscience & Nanotechnology

Microneedles-Based Transdermal Drug Delivery Systems: A Review

Ying Hao et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2017)

Add to Collection

Review Materials Science, Biomaterials

Mechanical properties of PNIPAM based hydrogels: A review

Muhammad Abdul Haq et al.

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery

Jicheng Yu et al.

NANO LETTERS (2017)

Add to Collection

Review Chemistry, Multidisciplinary

Dissolving Microneedle Patches for Dermal Vaccination

M. Leone et al.

PHARMACEUTICAL RESEARCH (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Insulin-Responsive Glucagon Delivery for Prevention of Hypoglycemia

Jicheng Yu et al.

SMALL (2017)

Add to Collection

Article Multidisciplinary Sciences

Microneedle-array patches loaded with dual mineralized protein/peptide particles for type 2 diabetes therapy

Wei Chen et al.

NATURE COMMUNICATIONS (2017)

Add to Collection

Review Oncology

Role of tumor microenvironment in tumorigenesis

Maonan Wang et al.

JOURNAL OF CANCER (2017)

Add to Collection

Article Materials Science, Biomaterials

H2O2-Responsive mesoporous silica nanoparticles integrated with microneedle patches for the glucose-monitored transdermal delivery of insulin

Bin Xu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

Add to Collection

Article Materials Science, Biomaterials

Near-infrared light triggered and separable microneedles for transdermal delivery of metformin in diabetic rats

Weijiang Yu et al.

JOURNAL OF MATERIALS CHEMISTRY B (2017)

Add to Collection

Article Multidisciplinary Sciences

Wearable/disposable sweat-based glucose monitoring device with multistage transdermal drug delivery module

Hyunjae Lee et al.

SCIENCE ADVANCES (2017)

Add to Collection

Article Immunology

A melanin-mediated cancer immunotherapy patch

Yanqi Ye et al.

SCIENCE IMMUNOLOGY (2017)

Add to Collection

Review Chemistry, Multidisciplinary

Design and Functionalization of the NIR-Responsive Photothermal Semiconductor Nanomaterials for Cancer Theranostics

Xiaojuan Huang et al.

ACCOUNTS OF CHEMICAL RESEARCH (2017)

Add to Collection

Article Nanoscience & Nanotechnology

Novel Approach of Using Near-Infrared Responsive PEGylated Gold Nanorod Coated Poly(L-lactide) Microneedles to Enhance the Antitumor Efficiency of Docetaxel-Loaded MPEG-PDLLA Micelles for Treating an A431 Tumor

Ying Hao et al.

ACS APPLIED MATERIALS & INTERFACES (2017)

Add to Collection

Article Chemistry, Multidisciplinary

H2O2-Responsive Vesicles Integrated with Transcutaneous Patches for Glucose-Mediated Insulin Delivery

Xiuli Hu et al.

ACS NANO (2017)

Add to Collection

Article Chemistry, Multidisciplinary

Near-Infrared Light-Activatable Microneedle System for Treating Superficial Tumors by Combination of Chemotherapy and Photothermal Therapy

Mei-Chin Chen et al.

ACS NANO (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Albumin-Bioinspired Gd:CuS Nanotheranostic Agent for In Vivo Photoacoustic/Magnetic Resonance Imaging-Guided Tumor-Targeted Photothermal Therapy

Weitao Yang et al.

ACS NANO (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery

Yanqi Ye et al.

ADVANCED MATERIALS (2016)

Add to Collection

Article Chemistry, Multidisciplinary

Light-Activated Hypoxia-Responsive Nanocarriers for Enhanced Anticancer Therapy

Chenggen Qian et al.

ADVANCED MATERIALS (2016)

Add to Collection

Review Engineering, Biomedical

Mechanisms and biomaterials in pH-responsive tumour targeted drug delivery: A review

Manju Kanamala et al.

BIOMATERIALS (2016)

Add to Collection

Review Chemistry, Multidisciplinary

Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species

Xiaoqiang Chen et al.

CHEMICAL SOCIETY REVIEWS (2016)

Add to Collection

Article Medicine, Research & Experimental

Hydrogel-Forming Microneedle Arrays Made from Light-Responsive Materials for On-Demand Transdermal Drug Delivery

John G. Hardy et al.

MOLECULAR PHARMACEUTICS (2016)

Add to Collection

Review Chemistry, Multidisciplinary

Microneedles: A New Frontier in Nanomedicine Delivery

Eneko Larraneta et al.

PHARMACEUTICAL RESEARCH (2016)

Add to Collection

Article Chemistry, Analytical

Fabrication of a Micro-Needle Array Electrode by Thermal Drawing for Bio-Signals Monitoring

Lei Ren et al.

SENSORS (2016)

Add to Collection

Review Pharmacology & Pharmacy

Near-infrared light-responsive inorganic nanomaterials for photothermal therapy

Zhihong Bao et al.

ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

Add to Collection

Article Engineering, Biomedical

Remotely triggered release of small molecules from LaB6@SiO2-loaded polycaprolactone microneedles

Mei-Chin Chen et al.

ACTA BIOMATERIALIA (2015)

Add to Collection

Article Biochemistry & Molecular Biology

Near-Infrared Light-Responsive Composite Microneedles for On-Demand Transdermal Drug Delivery

Mei-Chin Chen et al.

BIOMACROMOLECULES (2015)

Add to Collection

Article Endocrinology & Metabolism

Skin pH Is Lower in Type 1 Diabetes Subjects and Is Related to Glycemic Control of the Disease

Malgorzata Mackiewicz-Wysocka et al.

DIABETES TECHNOLOGY & THERAPEUTICS (2015)

Add to Collection

Review Pharmacology & Pharmacy

Thermoresponsive hydrogels in biomedical applications A seven-year update

Leda Klouda

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2015)

Add to Collection

Article Multidisciplinary Sciences

Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery

Jicheng Yu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Add to Collection

Article Chemistry, Multidisciplinary

Multifunctional Fe3O4@Polydopamine Core-Shell Nanocomposites for Intracellular mRNA Detection and Imaging-Guided Photothermal Therapy

Li-Sen Lin et al.

ACS NANO (2014)

Add to Collection

Review Biotechnology & Applied Microbiology

pH-Sensitive nano-systems for drug delivery in cancer therapy

Juan Liu et al.

BIOTECHNOLOGY ADVANCES (2014)

Add to Collection

Review Chemistry, Multidisciplinary

Near-infrared light-responsive nanomaterials in cancer therapeutics

Vijayakumar Shanmugam et al.

CHEMICAL SOCIETY REVIEWS (2014)

Add to Collection

Review Chemistry, Multidisciplinary

Current advances in the fabrication of microneedles for transdermal delivery

Sunaina Indermun et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Add to Collection

Article Chemistry, Multidisciplinary

Polyplex-releasing microneedles for enhanced cutaneous delivery of DNA vaccine

Nak Won Kim et al.

JOURNAL OF CONTROLLED RELEASE (2014)

Add to Collection

Article Chemistry, Multidisciplinary

Enzyme-responsive nanomaterials for controlled drug delivery

Quanyin Hu et al.

NANOSCALE (2014)

Add to Collection

Review Biotechnology & Applied Microbiology

3D bioprinting of tissues and organs

Sean V. Murphy et al.

NATURE BIOTECHNOLOGY (2014)

Add to Collection

Review Chemistry, Multidisciplinary

Magnetic responsive polymer composite materials

Julie Thevenot et al.

CHEMICAL SOCIETY REVIEWS (2013)

Add to Collection

Article Pharmacology & Pharmacy

Hydrogel-forming microneedle arrays exhibit antimicrobial properties: Potential for enhanced patient safety

Ryan F. Donnelly et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2013)

Add to Collection

Article Chemistry, Multidisciplinary

Plasmonic Gold Nanocrystals Coupled with Photonic Crystal Seamlessly on TiO2 Nanotube Photoelectrodes for Efficient Visible Light Photoelectrochemical Water Splitting

Zhonghai Zhang et al.

NANO LETTERS (2013)

Add to Collection

Review Pharmacology & Pharmacy

Photochemical mechanisms of light-triggered release from nanocarriers

Nadezda Fomina et al.

ADVANCED DRUG DELIVERY REVIEWS (2012)

Add to Collection

Article Engineering, Biomedical

Multidrug release based on microneedle arrays filled with pH-responsive PLGA hollow microspheres

Cherng-Jyh Ke et al.

BIOMATERIALS (2012)

Add to Collection

Review Biotechnology & Applied Microbiology

Reactive Oxygen Species in Health and Disease

Assim A. Alfadda et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2012)

Add to Collection

Article Pharmacology & Pharmacy

Characterization of Microchannels Created by Metal Microneedles: Formation and Closure

Haripriya Kalluri et al.

AAPS JOURNAL (2011)

Add to Collection

Article Chemistry, Multidisciplinary

Dissolving Microneedle Patch for Transdermal Delivery of Human Growth Hormone

Jeong Woo Lee et al.

SMALL (2011)

Add to Collection

Article Chemistry, Multidisciplinary

Multifunctional Hybrid Nanogel for Integration of Optical Glucose Sensing and Self-Regulated Insulin Release at Physiological pH

Weitai Wu et al.

ACS NANO (2010)

Add to Collection

Article Biochemistry & Molecular Biology

Hollow Microneedle Arrays for Intradermal Drug Delivery and DNA Electroporation

Lievin Daugimont et al.

JOURNAL OF MEMBRANE BIOLOGY (2010)

Add to Collection

Review Dermatology

The impact of the pH value on skin integrity and cutaneous wound healing

S. Schreml et al.

JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY (2010)

Add to Collection

Review Biochemistry & Molecular Biology

Enzyme-triggered nanomedicine: Drug release strategies in cancer therapy (Invited Review)

Thomas L. Andresen et al.

MOLECULAR MEMBRANE BIOLOGY (2010)

Add to Collection

Article Dermatology

A Clinical Investigation into the Relationship between Increased Periwound Skin Temperature and Local Wound Infection in Patients with Chronic Leg Ulcers

Marjorie Fierheller et al.

ADVANCES IN SKIN & WOUND CARE (2010)

Add to Collection

Article Endocrinology & Metabolism

Report of the Committee on the Classification and Diagnostic Criteria of Diabetes Mellitus

Yutaka Seino et al.

JOURNAL OF DIABETES INVESTIGATION (2010)

Add to Collection

Review Chemistry, Multidisciplinary

Magnetothermally-responsive Nanomaterials: Combining Magnetic Nanostructures and Thermally-Sensitive Polymers for Triggered Drug Release

Christopher S. Brazel

PHARMACEUTICAL RESEARCH (2009)

Add to Collection

Review Pharmacology & Pharmacy

Thermoresponsive hydrogels in biomedical applications

Leda Klouda et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2008)

Add to Collection

Review Biotechnology & Applied Microbiology

Transdermal drug delivery

Mark R. Prausnitz et al.

NATURE BIOTECHNOLOGY (2008)

Add to Collection

Review Multidisciplinary Sciences

Tissue engineering of replacement skin: the crossroads of biomaterials, wound healing, embryonic development, stem cells and regeneration

Anthony D. Metcalfe et al.

JOURNAL OF THE ROYAL SOCIETY INTERFACE (2007)

Add to Collection

Article Chemistry, Multidisciplinary

Enzyme-responsive polymer hydrogel particles for controlled release

Paul D. Thornton et al.

ADVANCED MATERIALS (2007)

Add to Collection

Review Dermatology

Tissue engineering for cutaneous wounds

Richard A. F. Clark et al.

JOURNAL OF INVESTIGATIVE DERMATOLOGY (2007)

Add to Collection

Article Chemistry, Multidisciplinary

Light-induced reversible formation of polymeric micelles

Hyung-il Lee et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)

Add to Collection

Article Engineering, Electrical & Electronic

A tapered hollow metallic microneedle array using backside exposure of SU-8

K Kim et al.

JOURNAL OF MICROMECHANICS AND MICROENGINEERING (2004)

Add to Collection

Article Dermatology

pH values in chronic wounds. Evaluation during modern wound therapy

J Dissemond et al.

HAUTARZT (2003)

Add to Collection

Article Pharmacology & Pharmacy

pH profiles in human skin: influence of two in vitro test systems for drug delivery testing

H Wagner et al.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS (2003)

Add to Collection

Review Multidisciplinary Sciences

Global and societal implications of the diabetes epidemic

P Zimmet et al.

NATURE (2001)

Add to Collection

© Peeref 2019-2024. All rights reserved.