Related references
Note: Only part of the references are listed.Drug development, Brazilian biodiversity and political choices: Where are we heading?
Paulo Michel Pinheiro Ferreira et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS (2023)
Pedunculagin isolated from Plinia cauliflora seeds exhibits genotoxic, antigenotoxic and cytotoxic effects in bacteria and human lymphocytes
Amanda Silva Fernandes et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2022)
Identification of bioactive compounds and cytogenotoxicity of the essential oil from the leaves of Croton heliotropiifolius Kunth
Katianne Soares Lopes et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2022)
Antistaphylococcal and antioxidant activities of bacteriocinogenic lactic acid bacteria and essential oil in goat coalho cheese
Tassio Jose de Oliveira Almeida et al.
JOURNAL OF APPLIED MICROBIOLOGY (2022)
Cecropia pachystachya Trecul: identification, isolation of secondary metabolites, in silico study of toxicological evaluation and interaction with the enzymes 5-LOX and α-1-antitrypsin
Penina Sousa Mourao et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2022)
Ethnobotanical and ethnopharmacological study of medicinal plants used by a traditional community in Brazil’s northeastern
P. K. A. Magalhães et al.
BRAZILIAN JOURNAL OF BIOLOGY (2021)
Essential Oil of Croton zehntneri Prevents Conduction Alterations Produced by Diabetes Mellitus on Vagus Nerve
Kerly Shamyra Silva-Alves et al.
PLANTS-BASEL (2021)
Chemical Constituents and Biological Activities of Croton heliotropiifolius Kunth
Priscilla Augusta de Sousa Fernandes et al.
ANTIBIOTICS-BASEL (2021)
Antidepressant activity of rose oxide essential oil: possible involvement of serotonergic transmission
Wcleubianne Matias Nascimento Maia et al.
HELIYON (2021)
PubChem in 2021: new data content and improved web interfaces
Sunghwan Kim et al.
NUCLEIC ACIDS RESEARCH (2021)
Physicochemical characterization and pharmacokinetic evaluation of rosuvastatin calcium incorporated solid lipid nanoparticles
Fawaz N. S. Al-Heibshy et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)
A novel strategy for prediction of human plasma protein binding using machine learning techniques
Yawen Yuan et al.
CHEMOMETRICS AND INTELLIGENT LABORATORY SYSTEMS (2020)
Computational Approaches in Preclinical Studies on Drug Discovery and Development
Fengxu Wu et al.
FRONTIERS IN CHEMISTRY (2020)
Cytotoxicity Assessment of Siparuna cymosa Essential Oil in the Presence of Myeloid Leukemia Cells
R. O. da Silva et al.
REVISTA VIRTUAL DE QUIMICA (2020)
Determination and prediction of permeability across intestinal epithelial cell monolayer of a diverse range of industrial chemicals/drugs for estimation of oral absorption as a putative marker of hepatotoxicity
Yusuke Kamiya et al.
TOXICOLOGY REPORTS (2020)
Chemical Composition of the Essential Oil Extracted from the Leaves of the Male and Female Individuals and Fruits of Schinus terebenthifolius
P. T. Silva et al.
REVISTA VIRTUAL DE QUIMICA (2019)
Characterisation of data resources for in silico modelling: benchmark datasets for ADME properties
K. R. Przybylak et al.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2018)
Effects of Caatinga Plant Extracts in Planktonic Growth and Biofilm Formation in Ralstonia solanacearum
Carolina Barbosa Malafaia et al.
MICROBIAL ECOLOGY (2018)
CHEMINFORMATICS: AN INTRODUCTION
Vinicius M. Alves et al.
QUIMICA NOVA (2018)
Use of micronucleus and comet assay to evaluate evaluate the genotoxicity of oregano essential oil (Origanum vulgare l. Virens) in rats orally exposed for 90 days.
Maria Llana-Ruiz-Cabello et al.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES (2018)
Novel candidate genes of the PARK7 interactome as mediators of apoptosis and acetylation in multiple sclerosis: An in silico analysis
George D. Vavougios et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2018)
Chemical Constituents from Croton Species and Their Biological Activities
Wen-Hui Xu et al.
MOLECULES (2018)
In silico ADME-Tox modeling: progress and prospects
Saeed Alqahtani
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2017)
In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development
Franco Lombardo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Antinociceptive Effect of the Essential Oil from Croton conduplicatus Kunth (Euphorbiaceae)
Raimundo Goncalves de Oliveira Junior et al.
MOLECULES (2017)
Antimicrobial, modulatory and chemical analysis of the oil of Croton limae
Tiago Rodrigues Leite et al.
PHARMACEUTICAL BIOLOGY (2017)
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
Antoine Daina et al.
SCIENTIFIC REPORTS (2017)
Drug Metabolism in Preclinical Drug Development: A Survey of the Discovery Process, Toxicology, and Computational Tools
Naiem T. Issa et al.
CURRENT DRUG METABOLISM (2017)
FAF-Drugs4: free ADME-tox filtering computations for chemical biology and early stages drug discovery
David Lagorce et al.
BIOINFORMATICS (2017)
Multiple resistance to carcinogens and xenobiotics: P-glycoproteins as universal detoxifiers
Thomas Efferth et al.
ARCHIVES OF TOXICOLOGY (2017)
Retention data of bile acids and their oxo derivatives in characterization of pharmacokinetic properties and in silico ADME modeling
Jovana Triftmovic et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)
Plant species as a therapeutic resource in areas of the savanna in the state of Pernambuco, Northeast Brazil
Manuele Eufrasio Saraiva et al.
JOURNAL OF ETHNOPHARMACOLOGY (2015)
Kv11.1 (hERG)-induced cardiotoxicity: a molecular insight from a binding kinetics study of prototypical Kv11.1 (hERG) inhibitors
Z. Yu et al.
BRITISH JOURNAL OF PHARMACOLOGY (2015)
The role of drug metabolizing enzymes in clearance
Li Di
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY (2014)
Antifungals and acetylcholinesterase inhibitors from the stem bark of Croton heliotropiifolius
M. M. F. Queiroz et al.
PHYTOCHEMISTRY LETTERS (2014)
Considering the impact drug-like properties have on the chance of success
Iskander Yusof et al.
DRUG DISCOVERY TODAY (2013)
Chemical predictive modelling to improve compound quality
John G. Cumming et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Antiulcerogenic effect of Croton urucurana Baillon bark
Katia Wolff Cordeiro et al.
JOURNAL OF ETHNOPHARMACOLOGY (2012)
Understanding drug-likeness
Oleg Ursu et al.
WILEY INTERDISCIPLINARY REVIEWS-COMPUTATIONAL MOLECULAR SCIENCE (2011)
Computational toxicology-a tool for early safety evaluation
Cedric Merlot
DRUG DISCOVERY TODAY (2010)
Human population studies with the exfoliated buccal micronucleus assay: Statistical and epidemiological issues
Marcello Ceppi et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2010)
Micronuclei frequency in peripheral blood lymphocytes of cancer patients:: A meta-analysis
G. Iarmarcovai et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2008)
TOXICITY IN AQUATIC ENVIRONMENTS: DISCUSSION AND EVALUATION METHODS
Carla Regina Costa et al.
QUIMICA NOVA (2008)
Origin of nuclear buds and micronuclei in normal and folate-deprived human lymphocytes
Hanna K. Lindberg et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2007)
An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans
Stefano Bonassi et al.
CARCINOGENESIS (2007)
hERG potassium channels and cardiac arrhythmia
MC Sanguinetti et al.
NATURE (2006)
Predictive model of blood-brain barrier penetration of organic compounds
XL Ma et al.
ACTA PHARMACOLOGICA SINICA (2005)
The role of absorption, distribution, metabolism, excretion and toxicity in drug discovery
J Lin et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2003)
Molecular properties that influence the oral bioavailability of drug candidates
DF Veber et al.
JOURNAL OF MEDICINAL CHEMISTRY (2002)
Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure-activity relationship (QSAR) with the Abraham descriptors
YH Zhao et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2001)
Drug design based on natural products.
CA Montanari et al.
QUIMICA NOVA (2001)
The in vitro micronucleus technique
M Fenech
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2000)
Acute toxicity test with Daphnia magna:: An alternative to mammals in the prescreening of chemical toxicity?
L Guilhermino et al.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY (2000)
Property distribution of drug-related chemical databases
TI Oprea
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2000)
Share Paper
