New Morphologic Findings Support Invasiveness Criteria in Small-Sized Nonmucinous Lepidic Adenocarcinoma: Commenting a Proposal From the International Association for the Study of Lung Cancer Pathology Committee

Article Oncology

Defining Morphologic Features of Invasion in Pulmonary Nonmucinous Adenocarcinoma With Lepidic Growth: A Proposal by the International Association for the Study of Lung Cancer Pathology Committee

Erik Thunnissen et al.

Summary: This study aimed to identify histologic features in tumors with lepidic growth pattern to establish criteria for distinguishing invasive from noninvasive areas. The analysis revealed that multilayered luminal epithelial cell growth and collapsed alveoli were the morphologic features that contributed to the interobserver variability.

JOURNAL OF THORACIC ONCOLOGY (2023)

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Article Oncology

The value of disease-free survival (DFS) and osimertinib in adjuvant non-small-cell lung cancer (NSCLC): an international Delphi consensus report

M. C. Hardenberg et al.

Summary: This study identified a consensus on the clinical and patient relevance of DFS in adjuvant NSCLC through a Delphi expert panel study, indicating that DFS is a clinically and patient-relevant endpoint in adjuvant therapy.

ESMO OPEN (2022)

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Article Oncology

An International Consensus on Actions to Improve Lung Cancer Survival: A Modified Delphi Method Among Clinical Experts in the International Cancer Benchmarking Partnership

Charlotte Lynch et al.

Summary: The International Cancer Benchmarking Partnership conducted background research showing international variation in lung cancer survival persists, particularly in early stage disease. Recommendations were developed through semi-structured interviews and a modified Delphi consensus model to optimize the management of lung cancer, focusing on initiatives such as screening, timely diagnosis, and developing Centers of Excellence. These recommendations, presented by an expert international lung cancer clinical network, provide key considerations for policymakers in ICBP countries and other comparable high-income countries in improving outcomes and management of lung cancer patients globally.

CANCER CONTROL (2022)

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Article Oncology

Treatment strategy optimization for patients with non-small-cell lung cancer harboring EGFR mutation: a Delphi consensus

D. Isla et al.

Summary: A consensus was established on the treatment strategy for aNSCLC patients with EGFRm through a Delphi survey and expert evaluation, highlighting the importance of determining EGFR status and selecting the optimal therapeutic option.

CLINICAL & TRANSLATIONAL ONCOLOGY (2021)

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Article Cardiac & Cardiovascular Systems

Definition and assessment of high risk in patients considered for lobectomy for stage I non-small cell lung cancer: The American Association for Thoracic Surgery expert panel consensus document

Arjun Pennathur et al.

Summary: Lobectomy is a standard treatment for stage I non-small cell lung cancer, but a significant proportion of patients may be at high risk for complications, including mortality. The expert panel identified important risk factors for assessing high risk patients, such as the need for supplemental oxygen, low diffusion capacity, frailty, and overall daily activity assessment. Age was determined to be less important in risk assessment relative to other factors, and a minimally invasive approach is increasingly critical in older populations to mitigate risk.

JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY (2021)

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Article Pathology