Related references
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Editorial Material
Infectious Diseases
David Hui
LANCET INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Emma K. Accorsi et al.
Summary: Assessing the performance of COVID-19 vaccines against the Omicron variant is crucial for public health guidance. This study found that receiving three doses of mRNA COVID-19 vaccine was associated with a lower likelihood of symptomatic SARS-CoV-2 infection compared to being unvaccinated or receiving two doses. These findings suggest that three doses of mRNA vaccine provide protection against both Omicron and Delta variants, though the protection against Omicron may be slightly lower.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2022)
Article
Medicine, General & Internal
Victoria Hall et al.
Summary: This study investigated the duration and effectiveness of immunity among healthcare workers in the United Kingdom. It found that two doses of the BNT162b2 vaccine provided high short-term protection against SARS-CoV-2 infection, but this protection significantly decreased after six months. However, infection-acquired immunity boosted by vaccination remained high, even more than one year after infection.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Letter
Medicine, General & Internal
Khitam Muhsen et al.
Summary: During a surge of Covid-19 cases in Israel, a rapid deployment of BNT162b2 booster injections in long-term care facilities over a 3-week period in July resulted in a 71% decrease in infection rates and an 80% decrease in hospitalization rates, while general population infection rates were increasing.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Medicine, General & Internal
Ariel Hammerman et al.
Summary: This retrospective cohort study in Israel found that receiving at least one dose of the BNT162b2 vaccine was associated with a significantly lower risk of recurrent infection among patients who had recovered from Covid-19. Vaccine effectiveness was similar for one dose and two doses.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Immunology
Sandro M. Hirabara et al.
Summary: This review addresses key issues regarding SARS-CoV-2 variants, including the characteristics of variants with mutations in the S gene, evasion of neutralizing antibodies, potential risks of new pandemic waves, and prospects for further research and actions to prevent or reduce the impact of new variants during the current COVID-19 pandemic.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2022)
Article
Immunology
Adeel A. Butt et al.
Summary: While the relative vaccine effectiveness of a booster dose of the COVID-19 mRNA vaccine in preventing infection against the Omicron variant is low, it is substantial in preventing hospitalization and high in preventing the most severe/critical disease.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Medicine, General & Internal
Fiona P. Havers et al.
Summary: Understanding the factors that contribute to hospitalization in vaccinated individuals is crucial for combating COVID-19. This study found that unvaccinated adults were more likely to be hospitalized compared to vaccinated adults, with the lowest hospitalization rates observed in those who had received a booster dose.
JAMA INTERNAL MEDICINE
(2022)
Article
Medicine, General & Internal
Marcello Morciano et al.
Summary: By August 7, 2020, there were 29,542 (95% CI 25,176 to 33,908) excess deaths in all care homes in England. Excess deaths accounted for 6.5% (95% CI 5.5 to 7.4%) of all care home beds, with a higher rate in nursing homes (8.4%) compared to residential homes (4.6%). 64.7% (95% CI 56.4 to 76.0%) of excess deaths were confirmed/suspected COVID-19 cases. The odds of experiencing COVID-19 attributable deaths were higher in homes providing nursing services, with older residents and/or dementia patients, larger homes, and belonging to a large provider/brand, but not significantly associated with for-profit status.
Article
Medicine, General & Internal
Andrew P. Costa et al.
Summary: This study investigated the epidemiology of SARS-CoV-2 infection in retirement homes in Ontario, Canada. It found that identifiable characteristics of retirement homes are independently associated with outbreaks of SARS-CoV-2 infection, providing valuable information for risk identification and prioritization for vaccination.
CANADIAN MEDICAL ASSOCIATION JOURNAL
(2021)
