The impact of recurrence timing and tumor burden score on overall survival among patients undergoing repeat hepatectomy for colorectal liver metastases

Article Surgery

Hepatectomy is associated with improved oncologic outcomes in recurrent colorectal liver metastases: A propensity-matched analysis

Thomas L. Sutton et al.

Summary: Repeat hepatic resection is associated with improved post-recurrence overall survival compared to systemic treatment alone, particularly for patients with a low number of liver metastases.

SURGERY (2023)

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Article Surgery

Simultaneous versus staged resection for synchronous colorectal liver metastases: The win ratio approach

Yutaka Endo et al.

Summary: In this study, we used the win ratio (WR) to compare the outcomes of simultaneous and staged surgical treatment for synchronous colorectal liver metastases (sCRLM). The results showed that staged resection had a higher WR than simultaneous resection, indicating its superiority for treating sCRLM.

AMERICAN JOURNAL OF SURGERY (2023)

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Article Oncology

Cancer statistics, 2022

Rebecca L. Siegel et al.

Summary: Each year, the American Cancer Society compiles data on cancer occurrence and outcomes in the United States. The latest data shows that breast and prostate cancer progress has stagnated, while lung cancer has shown improvements in survival rates. Lung cancer incidence for advanced disease has declined while localized-stage rates have increased, resulting in higher survival rates. Mortality patterns align with incidence trends, with lung cancer deaths declining rapidly, breast cancer deaths slowing, and prostate cancer deaths stabilizing.

CA-A CANCER JOURNAL FOR CLINICIANS (2022)

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Article Oncology

Reconsideration of indications for third hepatectomy for colorectal liver metastases

Jiro Kimura et al.

Summary: It remains unclear which patients with recurrence after a second hepatectomy will benefit from a third hepatectomy. Factors such as tumor size and CA 19-9 level can affect long-term outcomes.

JOURNAL OF SURGICAL ONCOLOGY (2022)

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Article Oncology

Outcomes after repeat hepatectomy for colorectal liver metastases from the colorectal liver operative metastasis international collaborative (COLOMIC)

Cristian D. Valenzuela et al.

Summary: Second hepatectomy is beneficial in cases of hepatic recurrence in colorectal liver metastasis (CLM). Factors such as obesity, tobacco use, and high intraoperative blood loss are associated with a significant risk of death.

JOURNAL OF SURGICAL ONCOLOGY (2022)

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Review Oncology

Repeat hepatectomy justified in patients with early recurrence of colorectal cancer liver metastases: A systematic review and meta-analysis

Tessa Hellingman et al.

Summary: The review and meta-analysis show that the disease-free interval is a prognostic factor for overall survival in patients undergoing repeat hepatectomy for recurrent CRLM, but it should not be the only criterion for selecting patients for repeat hepatectomy.

CANCER EPIDEMIOLOGY (2021)

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Article Surgery

Surgical and oncologic outcomes following repeat hepatic resection of colorectal liver metastasis: Who benefits?

Liam H. Wong et al.

Summary: Repeat hepatectomy for recurrent colorectal liver metastases can be performed safely, with additional post-operative chemotherapy associated with improved outcomes. Poor survival following repeat hepatectomy is independently associated with certain factors including tumor size and time to recurrence.

AMERICAN JOURNAL OF SURGERY (2021)

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Editorial Material Surgery

Proposal of a New Comprehensive Notation for Hepatectomy The New World'' Terminology

Masato Nagino et al.

ANNALS OF SURGERY (2021)

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Article Oncology

Repeat Local Treatment of Recurrent Colorectal Liver Metastases, the Role of Neoadjuvant Chemotherapy: An Amsterdam Colorectal Liver Met Registry (AmCORE) Based Study

Madelon Dijkstra et al.

Summary: This study found that adding neoadjuvant chemotherapy before repeat local treatment for colorectal liver metastases did not improve survival rates, recurrence rates, or impact complications and hospital stay duration. The results do not support routine use of neoadjuvant chemotherapy before repeat local treatment.

CANCERS (2021)

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Article Oncology

Survival Benefit of Repeat Local Treatment in Patients Suffering From Early Recurrence of Colorectal Cancer Liver Metastases

Tessa Hellingman et al.

Summary: Repeat local treatment should be considered in patients suffering from early recurrence of colorectal cancer liver metastases. A multimodality approach, consisting of neoadjuvant systemic therapy followed by repeat local treatment, appeared to offer favorable outcomes for patients with recurrence within 4 months following initial local treatment of colorectal cancer liver metastases.

CLINICAL COLORECTAL CANCER (2021)

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Article Surgery

Recurrent colorectal liver metastasis patients could benefit from repeat hepatic resection

Wei Liu et al.

Summary: This study investigated predictive factors for survival outcomes in recurrent colorectal liver metastasis patients. Factors such as primary lymph node positivity, tumor size > 3 cm, early recurrence, RAS gene mutation, and lack of local treatment were identified as independent risk factors for survival outcomes. A nomogram based on these factors showed good predictive ability.

BMC SURGERY (2021)

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Editorial Material Surgery