4.7 Article

Development of a Simple and Stable NanoESI Spray System Using Suction Wind from the MS Inlet

Journal

JOURNAL OF PROTEOME RESEARCH
Volume 22, Issue 5, Pages 1564-1569

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.jproteome.3c00146

Keywords

nanoESI; nanoLC; spray InSpIon; K562 cells

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In this study, a new insertion spray ionization (InSpIon) system was developed, which improved the reproducibility of proteome analysis by stabilizing the spray with a spray tip inserted into the InSpIon tube.
Improving the reproducibility of proteome analysis systems presents a challenge; therefore, in this study, we developed a new insertion spray ionization (InSpIon) system wherein an InSpIon tube was designed with a spray tip inserted into the tube. This system stabilized the spray and subsequently improved the reproducibility of the analysis.

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