4.4 Article

Guidance for the treatment and prevention of obstetric-associated venous thromboembolism

Journal

JOURNAL OF THROMBOSIS AND THROMBOLYSIS
Volume 41, Issue 1, Pages 92-128

Publisher

SPRINGER
DOI: 10.1007/s11239-015-1309-0

Keywords

Pregnancy; Obstetric; Venous thromboembolism; Pulmonary embolism; Deep vein thrombosis; Prophylaxis; Anticoagulants

Funding

  1. Boehringer Ingelheim
  2. Daiichi Sankyo
  3. Janssen Pharmaceuticals

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Venous thromboembolism (VTE), which may manifest as pulmonary embolism (PE) or deep vein thrombosis (DVT), is a serious and potentially fatal condition. Treatment and prevention of obstetric-related VTE is complicated by the need to consider fetal, as well as maternal, wellbeing when making management decisions. Although absolute VTE rates in this population are low, obstetric-associated VTE is an important cause of maternal morbidity and mortality. This manuscript, initiated by the Anticoagulation Forum, provides practical clinical guidance on the prevention and treatment of obstetric-associated VTE based on existing guidelines and consensus expert opinion based on available literature where guidelines are lacking.

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