4.6 Review

The design and synthesis of new synthetic low-molecular-weight heparins

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

De novo synthesis of a narrow size distribution low-molecular-weight heparin

Kasemsiri Chandarajoti et al.

GLYCOBIOLOGY (2014)

Review Biochemistry & Molecular Biology

Chemoenzymatic synthesis of heparan sulfate and heparin

Jian Liu et al.

NATURAL PRODUCT REPORTS (2014)

Article Biochemistry & Molecular Biology

Homogeneous low-molecular-weight heparins with reversible anticoagulant activity

Yongmei Xu et al.

NATURE CHEMICAL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Use of biosynthetic enzymes in heparin and heparan sulfate synthesis

Elizabeth P. Chappell et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2013)

Review Hematology

Interplay between coagulation and vascular inflammation in sickle cell disease

Erica Sparkenbaugh et al.

BRITISH JOURNAL OF HAEMATOLOGY (2013)

Article Chemistry, Organic

First Gram-Scale Synthesis of a Heparin-Related Dodecasaccharide

Steen U. Hansen et al.

ORGANIC LETTERS (2013)

Editorial Material Pharmacology & Pharmacy

Synthetic heparin

Robert J. Linhardt et al.

CURRENT OPINION IN PHARMACOLOGY (2012)

Article Biochemistry & Molecular Biology

Chemoenzymatic Synthesis of Heparin Oligosaccharides with both Anti-factor Xa and Anti-factor IIa Activities

Yongmei Xu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Biochemistry & Molecular Biology

Probing Structural Selectivity of Synthetic Heparin Binding to Stabilin Protein Receptors

Elizabeth H. Pempe et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Multidisciplinary Sciences

Dissecting the substrate recognition of 3-O-sulfotransferase for the biosynthesis of anticoagulant heparin

Andrea F. Moon et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Hematology

Protamine reversal of low molecular weight heparin: clinically effective?

Joost J. van Veen et al.

BLOOD COAGULATION & FIBRINOLYSIS (2011)

Article Biochemistry & Molecular Biology

The Dominating Role of N-Deacetylase/N-Sulfotransferase 1 in Forming Domain Structures in Heparan Sulfate

Juzheng Sheng et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2011)

Article Multidisciplinary Sciences

Chemoenzymatic Synthesis of Homogeneous Ultralow Molecular Weight Heparins

Yongmei Xu et al.

SCIENCE (2011)

Article Cell Biology

Heparan Sulfate Proteoglycans

Stephane Sarrazin et al.

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2011)

Article Biotechnology & Applied Microbiology

In vitro synthesis of heparosan using recombinant Pasteurella multocida heparosan synthase PmHS2

Anais A. E. Chavaroche et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2010)

Article Biochemistry & Molecular Biology

Chemoenzymatic Design of Heparan Sulfate Oligosaccharides

Renpeng Liu et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Biochemistry & Molecular Biology

Design of biologically active heparan sulfate and heparin using an enzyme-based approach

Sherket Peterson et al.

NATURAL PRODUCT REPORTS (2009)

Review Biochemistry & Molecular Biology

Lessons learned from the contamination of heparin

Haiying Liu et al.

NATURAL PRODUCT REPORTS (2009)

Article Gastroenterology & Hepatology

Liver sinusoidal endothelial cells are the principal site for elimination of unfractionated heparin from the circulation

Cristina Ionica Oie et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)

Review Hematology

Heparin-induced thrombocytopenia: a historical perspective

John G. Kelton et al.

BLOOD (2008)

Review Biochemistry & Molecular Biology

The Structure of Glycosaminoglycans and their Interactions with Proteins

Neha S. Gandhi et al.

CHEMICAL BIOLOGY & DRUG DESIGN (2008)

Article Biochemistry & Molecular Biology

The human hyaluronan receptor for endocytosis (HARE/Stabilin-2) is a systemic clearance receptor for heparin

Edward N. Harris et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biotechnology & Applied Microbiology

Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events

Marco Guerrini et al.

NATURE BIOTECHNOLOGY (2008)

Article Medicine, General & Internal

Outbreak of Adverse Reactions Associated with Contaminated Heparin

David B. Blossom et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Medicine, General & Internal

Contaminated heparin associated with adverse clinical events and activation of the contact system

Takashi Kei Kishimoto et al.

NEW ENGLAND JOURNAL OF MEDICINE (2008)

Article Multidisciplinary Sciences

Redirecting the substrate specificity of heparan sulfate 2-O-sulfotransferase by structurally guided mutagenesis

Heather N. Bethea et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Biochemistry & Molecular Biology

Chemoenzymatic synthesis with distinct Pasteurella heparosan synthases -: Monodisperse polymers and unnatural structures

Alison E. Sismey-Ragatz et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Using an enzymatic combinatorial approach to identify anticoagulant heparan sulfate structures

Jinghua Chen et al.

CHEMISTRY & BIOLOGY (2007)

Review Cardiac & Cardiovascular Systems

Beyond unfractionated heparin and warfarin - Current and future advances

Jack Hirsh et al.

CIRCULATION (2007)

Review Multidisciplinary Sciences

Heparan sulphate proteoglycans fine-tune mammalian physiology

Joseph R. Bishop et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Determination of the substrate specificities of N-acetyl-D-glucosaminyltransferase

Miao Chen et al.

BIOCHEMISTRY (2006)

Review Medicine, General & Internal

Meta-analysis: Low-molecular-weight heparin and bleeding in patients with severe renal insufficiency

W Lim et al.

ANNALS OF INTERNAL MEDICINE (2006)

Article Hematology

Fondaparinux: A potential new therapy for HIT

KHM Kuo et al.

HEMATOLOGY (2005)

Review Chemistry, Multidisciplinary

A synthetic antithrombin III binding pentasaccharide is now a drug! What comes next?

M Petitou et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)

Article Biochemistry & Molecular Biology

Substrate specificity of the heparan sulfate hexuronic acid 2-O-sulfotransferase

JH Rong et al.

BIOCHEMISTRY (2001)

Article Multidisciplinary Sciences

Specificities of heparan sulphate proteoglycans in developmental processes

N Perrimon et al.

NATURE (2000)