Journal
JOURNAL OF PEDIATRICS
Volume 257, Issue -, Pages -Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.jpeds.2023.02.006
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Among 365 children diagnosed with Kawasaki disease, only 5 (1.4%) had splenomegaly, with 2 of them complicated by macrophage activation syndrome and 3 ultimately diagnosed with alternative systemic illness. Splenomegaly is an atypical manifestation in Kawasaki disease and may indicate underlying complications such as macrophage activation syndrome or other diagnoses.
Among the 365 children diagnosed as having Kawasaki disease (KD), only 5 children (1.4%) presented with splenomegaly: 2 complicated by macrophage activation syndrome and 3 ultimately received a diagnosis of alternative systemic illness. Splenomegaly is atypical in KD and a potential marker of an underling complication, namely macrophage activation syndrome, or diagnosis other than KD.
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