Sulfur-Mediated Formal Allylic C-H Cyclopropanation of α-Methylstyrenes

Allylic C-H cyclopropanation of a-methylstyrene and its derivatives was realized through a one-pot two-step sequence, formally converting two aliphatic C-H bonds to C-C bonds with a good yield and high diastereoselectivity, thus providing a quick entry to the synthetically useful vinyl cyclopropane structures.

Automated summary

A one-pot two-step reaction sequence enables allylic C-H cyclopropanation of a-methylstyrene and its derivatives, converting two aliphatic C-H bonds to C-C bonds with high diastereoselectivity and good yield, offering a convenient method for the synthesis of vinyl cyclopropane structures.