A novel colorimetric and ratiometric fluorescent probe for detection of Cu2+with large stokes shift in complete aqueous solution

A novel colorimetric and ratiometric fluorescent probe 1 for Cu2 + was designed and synthesized. 1 ex-hibited maximum absorption and fluorescence emission peaks at 385 nm and 495 nm respectively, with large Stokes shift of 110 nm. In sensing of Cu2 +, the maximum absorption and fluorescence emission peaks generated bathochromic shift to 415 nm and 560 nm respectively, due to the Cu2 +-induced hy-drolysis reaction of the picolinate moiety in 1. Meanwhile, the solution of 1 turned from pale yellow to yellow in visible light and from pale green to orange under a 365 nm UV lamp. 1 displayed remarkable change in the ratio (F560 nm/F495 nm) of the fluorescence intensity (R/R0 up to 23-fold), high sensitivity (detection limit of 0.62 mu M), fast response time (within 2 min), and excellent selectivity for Cu2 + over other metal ions in complete aqueous solution.(c) 2023 Elsevier B.V. All rights reserved.

Automated summary

A novel colorimetric and ratiometric fluorescent probe 1 was designed and synthesized for the detection of Cu2+. Probe 1 exhibited maximum absorption and fluorescence emission peaks at 385 nm and 495 nm, respectively, with a large Stokes shift of 110 nm. In the presence of Cu2+, a bathochromic shift to 415 nm and 560 nm was observed in the absorption and fluorescence emission peaks, respectively, due to the Cu2+-induced hydrolysis reaction. The probe showed a significant change in the fluorescence intensity ratio (F560 nm/F495 nm), with high sensitivity, fast response time, and excellent selectivity for Cu2+ over other metal ions in aqueous solution.