Related references
Note: Only part of the references are listed.1,2,3-Benzoxathiazine-2,2-dioxides - effective inhibitors of human carbonic anhydrases
Jekaterina Ivanova et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2023)
Aromatic Sulfonamides including a Sulfonic Acid Tail: New Membrane Impermeant Carbonic Anhydrase Inhibitors for Targeting Selectively the Cancer-Associated Isoforms
Simone Giovannuzzi et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes
Gioele Vannozzi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
A Series of Thiadiazolyl-Benzenesulfonamides Incorporating an Aromatic Tail as Isoform-Selective, Potent Carbonic Anhydrase II/XII Inhibitors
Erden Banoglu et al.
CHEMMEDCHEM (2022)
Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases
Baijayantimala Swain et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Discovery of new carbonic anhydrase IX inhibitors as anticancer agents by toning the hydrophobic and hydrophilic rims of the active site to encounter the dual-tail approach
Haytham O. Tawfik et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII
Alessandro Bonardi et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2022)
Carbonic Anhydrase inhibitors bearing organotelluride moieties as novel agents for antitumor therapy
Andrea Petreni et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2022)
Cancer Therapeutic Targeting of Hypoxia Induced Carbonic Anhydrase IX: From Bench to Bedside
Paul C. McDonald et al.
CANCERS (2022)
α-CAs from Photosynthetic Organisms
Emma Langella et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2022)
Design and synthesis of some new benzoylthioureido phenyl derivatives targeting carbonic anhydrase enzymes
Mazin A. A. Najm et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2022)
Design and synthesis of benzothiazole-based SLC-0111 analogues as new inhibitors for the cancer-associated carbonic anhydrase isoforms IX and XII
Tarfah Al-Warhi et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2022)
Discovery of a Potent and Highly Selective Dipeptidyl Peptidase IV and Carbonic Anhydrase Inhibitor as Antidiabesity Agents Based on Repurposing and Morphing of WB-4101
Angelica Artasensi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
One-Pot Procedure for the Synthesis of Asymmetric Substituted Ureido Benzene Sulfonamides as Effective Inhibitors of Carbonic Anhydrase Enzymes
Gioele Vannozzi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2022)
Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion
Abdeslem Bouzina et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Carbonic anhydrase inhibitors: an update on experimental agents for the treatment and imaging of hypoxic tumors
Claudiu T. Supuran
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2021)
Determination of intracellular protein-ligand binding affinity by competition binding in-cell NMR
Enrico Luchinat et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2021)
Glyco-Coated CdSe/ZnS Quantum Dots as Nanoprobes for Carbonic Anhydrase IX Imaging in Cancer Cells
Giacomo Biagiotti et al.
ACS APPLIED NANO MATERIALS (2021)
Modulating the Efficacy of Carbonic Anhydrase Inhibitors through Fluorine Substitution
Emanuela Berrino et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)
An overview on the recently discovered iota-carbonic anhydrases
Alessio Nocentini et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2021)
Emerging role of carbonic anhydrase inhibitors
Claudiu T. Supuran
CLINICAL SCIENCE (2021)
Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase
Alessio Nocentini et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2021)
Aryl derivatives of 3H-1,2-benzoxathiepine 2,2-dioxide as carbonic anhydrase inhibitors
Aleksandrs Pustenko et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase
Mikhail Krasavin et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors
Aleksandrs Pustenko et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
Combining carbonic anhydrase and thioredoxin reductase inhibitory motifs within a single molecule dramatically increases its cytotoxicity
Mikhail Krasavin et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
Benzoxepinones: A new isoform-selective class of tumor associated carbonic anhydrase inhibitors
Aiga Grandane et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2020)
Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII
Aiga Grandane et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment
Andrea Angeli et al.
METABOLITES (2020)
Advances in the structural annotation of human carbonic anhydrases and impact on future drug discovery
Alessio Nocentini et al.
EXPERT OPINION ON DRUG DISCOVERY (2019)
Sulfocoumarins, specific carbonic anhydrase IX and XII inhibitors, interact with cancer multidrug resistant phenotype through pH regulation and reverse P-glycoprotein mediated resistance
Ana Podolski-Renic et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Atropisomerism in medicinal chemistry: challenges and opportunities
Sean T. Toenjes et al.
FUTURE MEDICINAL CHEMISTRY (2018)
Carbonic anhydrase inhibitors as emerging agents for the treatment and imaging of hypoxic tumors
Claudiu T. Supuran
EXPERT OPINION ON INVESTIGATIONAL DRUGS (2018)
Advances in structure-based drug discovery of carbonic anhydrase inhibitors
Claudiu T. Supuran
EXPERT OPINION ON DRUG DISCOVERY (2017)
3H-1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors
Aleksandrs Pustenko et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)
Synthesis, biological activity and multiscale molecular modeling studies for coumaryl-carboxamide derivatives as selective carbonic anhydrase IX inhibitors
Belma Zengin Kurt et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2017)
5-Substituted-benzylsulfanyl-thiophene-2-sulfonamides with effective carbonic anhydrase inhibitory activity: Solution and crystallographic investigations
Jekaterina Ivanova et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2017)
7-Aryl-triazolyl-substituted sulfocoumarins are potent, selective inhibitors of the tumor-associated carbonic anhydrase IX and XII
Alessio Nocentini et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2016)
How many carbonic anhydrase inhibition mechanisms exist?
Claudiu T. Supuran
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2016)
Structure and function of carbonic anhydrases
Claudiu T. Supuran
BIOCHEMICAL JOURNAL (2016)
6-Substituted Sulfocoumarins Are Selective Carbonic Anhdydrase IX and XII Inhibitors with Significant Cytotoxicity against Colorectal Cancer Cells
Aiga Grandane et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Efficient Expression and Crystallization System of Cancer-Associated Carbonic Anhydrase Isoform IX
Janis Leitans et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor
V. Alterio et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
7-Substituted-sulfocoumarins are isoform-selective, potent carbonic anhydrase II inhibitors
Muhammet Tanc et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Characterization of human carbonic anhydrase XII stability and inhibitor binding
Vaida Jogaite et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Structure, function and applications of carbonic anhydrase isozymes
Md Imtaiyaz Hassan et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Sulfocounnarins (1,2-Benzoxathiine-2,2-dioxides): A Class of Potent and Isoform-Selective Inhibitors of Tumor-Associated Carbonic Anhydrases
Kaspars Tars et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Overexpression of carbonic anhydrase II and Ki-67 proteins in prognosis of gastrointestinal stromal tumors
Li-Cheng Liu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2013)
JLigand: a graphical tool for the CCP4 template-restraint library
Andrey A. Lebedev et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
Vincenzo Alterio et al.
CHEMICAL REVIEWS (2012)
(In)organic anions as carbonic anhydrase inhibitors
Giuseppina De Simone et al.
JOURNAL OF INORGANIC BIOCHEMISTRY (2012)
Antimetastatic Effect of Sulfamate Carbonic Anhydrase IX Inhibitors in Breast Carcinoma Xenografts
Roben G. Gieling et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM
T. Geoff G. Battye et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2011)
REFMAC5 for the refinement of macromolecular crystal structures
Garib N. Murshudov et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2011)
An improved procedure for the synthesis of arylboronates by palladium-catalyzed coupling reaction of aryl halides and bis(pinacolato)diboron in polyethylene glycol
Jie Lu et al.
APPLIED ORGANOMETALLIC CHEMISTRY (2011)
Glycosyl Coumarin Carbonic Anhydrase IX and XII Inhibitors Strongly Attenuate the Growth of Primary Breast Tumors
Nadia Touisni et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Molecular replacement with MOLREP
Alexei Vagin et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
7,8-Disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range
Alfonso Maresca et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II
Alfonso Maresca et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)
The Coumarin-Binding Site in Carbonic Anhydrase Accommodates Structurally Diverse Inhibitors: The Antiepileptic Lacosamide As an Example and Lead Molecule for Novel Classes of Carbonic Anhydrase Inhibitors
Claudia Temperini et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins
Alfonso Maresca et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Non-Zinc Mediated Inhibition of Carbonic Anhydrases: Coumarins Are a New Class of Suicide Inhibitors
Alfonso Maresca et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
Vincenzo Alterio et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
Claudiu T. Supuran
NATURE REVIEWS DRUG DISCOVERY (2008)
Scaling and assessment of data quality
P Evans
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)
Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides
D Vullo et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Carbonic anhydrase inhibitors: The first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX
S Pastorekova et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Coot:: model-building tools for molecular graphics
P Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2004)
Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells
DA Whittington et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Share Paper
